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Hubungan Merokok dengan Kejadian Hipertensi pada Laki-Laki Usia 35-65 Tahun di Kota Padang Yashinta Octavian Gita Setyanda; Delmi Sulastri; Yuniar Lestari
Jurnal Kesehatan Andalas Vol 4, No 2 (2015)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v4i2.268

Abstract

AbstrakHipertensi merupakan salah satu penyebab kematian tertinggi pada masyarakat di dunia. Penyakit ini disebut juga the silent killer. Prevalensi hipertensi telah mencapai angka 31,7% dari semua penduduk. Peningkatan ini diakibatkan perubahan gaya hidup yang salah satunya merokok. Tujuan penelitian ini untuk mengetahui hubungan antara kebiasaan merokok termasuk lama merokok, jumlah rokok dan jenis rokok dengan hipertensi. Desain penelitian berupa cross-sectional study. Populasi adalah laki-laki yang berusia 35-65 tahun di empat kecamatan terpilih di kota Padang. Jumlah subjek sebanyak 92 orang yang diambil secara multi stage random sampling. Instrumen dalam penelitian ini ialah kuesioner untuk data responden dan karakteristik kebiasaan merokok, serta sphygmomanometer untuk mengukur tekanan darah. Data dianalisis dengan uji chi-square dengan p < 0,05 untuk signifikansi. Hasil penelitian didapatkan ada hubungan antara kebiasaan merokok dengan hipertensi (p=0,003) yaitu dipengaruhi oleh lama merokok (p=0,017) dan jenis rokok (p=0,017), tetapi tidak terdapat hubungan antara jumlah rokok dengan kejadian hipertensi (p=0,412). Oleh karena kebiasaan merokok meningkatkan risiko hipertensi, penyuluhan kesehatan tentang risiko peningkatan tekanan darah terhadap penderita hipertensi yang memiliki kebiasaan merokok harus dilakukan. Hal ini diperlukan agar terjadi penurunan angka kejadian hipertensi.Kata Kunci: hipertensi, kebiasaan merokok, lama merokok, jumlah rokok, jenis rokok AbstractHypertension is one of the major causes of death in the world. This disease is called silent killer. The prevalence of hypertension has reached 31.7% of the population. It increases because of lifestyle changes, one of them is smoking. The objective of this study was to determine the association between smoking habits including duration of smoking, number of cigarettes, and type of cigarettes with hypertension. The research design was cross-sectional study. The population was 35-65 years old men in four selected districts in Padang. There were 92 subjects who were taken by multi-stage random sampling. The instruments of this research were questionnaire for data of respondents and smoking habit characteristics, also sphygmomanometer for blood pressure measurements. Data were analyzed by chi-square test with p value < 0.05 for significance. The result of this study showed that there is association between smoking habit and hypertension (p=0.003) which is influenced by duration of smoking (p=0.017) and type of smoking (p=0.017), but there is no association between number of cigarettes with the incidence of hypertension (p=0.412). As smoking habits increase the risk of hypertension, health promotion about the risk of blood pressure increasing in the patient who has a smoking habit should be done. It is important in order to decrease the incidence of hypertension.Keywords: hypertension, duration of smoking, number of cigarettes, type of cigarettes
The Role of NT-proBNP in the Diagnosis of Peripartum Cardiomyopathy with Multiple Left Ventricular Thrombus: A Case Report Yashinta Octavian Gita Setyanda; Yaswir, Rismawati
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 10 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i10.1090

Abstract

Background: Peripartum cardiomyopathy (PPCM) is a rare but serious condition characterized by left ventricular dysfunction in late pregnancy or early postpartum. Early diagnosis is essential to prevent complications such as thromboembolism. N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a promising biomarker for the diagnosis of PPCM. Case presentation: An 18-year-old female presented with progressive shortness of breath and generalized edema. Physical examination and echocardiography revealed acute heart failure with multiple left ventricular thrombus. Very high levels of NT-proBNP (1,796 pg/mL) supported the diagnosis of PPCM. The patient was successfully treated with standard heart failure therapy and anticoagulants. Conclusion: This case report highlights the importance of NT-proBNP in the early diagnosis of PPCM and detecting of thromboembolic complications. Significant increases in NT-proBNP levels, even without obvious symptoms, should be promptly evaluated for PPCM, especially in high-risk populations.
Screening and Identification of Erythrocyte Antibodies: A Narrative Literature Review Yashinta Octavian Gita Setyanda; Rofinda, Zelly Dia
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 10 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i10.1091

Abstract

Red blood cell (RBC) alloimmunization, the development of antibodies against foreign red blood cell antigens, is a critical concern in transfusion medicine. Alloantibodies can lead to adverse transfusion reactions, including hemolytic disease of the fetus and newborn (HDFN) and delayed hemolytic transfusion reactions (DHTR). This comprehensive literature review explores the intricacies of RBC alloimmunization, focusing on the screening and identification of erythrocyte antibodies. We delve into the prevalence and clinical significance of various alloantibodies, the underlying immunological mechanisms, and the evolution of laboratory techniques for their detection. Additionally, we discuss the challenges and future directions in managing alloimmunization, emphasizing the importance of personalized medicine and innovative approaches to ensure safe and effective blood transfusions.
The Role of NT-proBNP in the Diagnosis of Peripartum Cardiomyopathy with Multiple Left Ventricular Thrombus: A Case Report Yashinta Octavian Gita Setyanda; Yaswir, Rismawati
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 10 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i10.1090

Abstract

Background: Peripartum cardiomyopathy (PPCM) is a rare but serious condition characterized by left ventricular dysfunction in late pregnancy or early postpartum. Early diagnosis is essential to prevent complications such as thromboembolism. N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a promising biomarker for the diagnosis of PPCM. Case presentation: An 18-year-old female presented with progressive shortness of breath and generalized edema. Physical examination and echocardiography revealed acute heart failure with multiple left ventricular thrombus. Very high levels of NT-proBNP (1,796 pg/mL) supported the diagnosis of PPCM. The patient was successfully treated with standard heart failure therapy and anticoagulants. Conclusion: This case report highlights the importance of NT-proBNP in the early diagnosis of PPCM and detecting of thromboembolic complications. Significant increases in NT-proBNP levels, even without obvious symptoms, should be promptly evaluated for PPCM, especially in high-risk populations.
Screening and Identification of Erythrocyte Antibodies: A Narrative Literature Review Yashinta Octavian Gita Setyanda; Rofinda, Zelly Dia
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 10 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i10.1091

Abstract

Red blood cell (RBC) alloimmunization, the development of antibodies against foreign red blood cell antigens, is a critical concern in transfusion medicine. Alloantibodies can lead to adverse transfusion reactions, including hemolytic disease of the fetus and newborn (HDFN) and delayed hemolytic transfusion reactions (DHTR). This comprehensive literature review explores the intricacies of RBC alloimmunization, focusing on the screening and identification of erythrocyte antibodies. We delve into the prevalence and clinical significance of various alloantibodies, the underlying immunological mechanisms, and the evolution of laboratory techniques for their detection. Additionally, we discuss the challenges and future directions in managing alloimmunization, emphasizing the importance of personalized medicine and innovative approaches to ensure safe and effective blood transfusions.