Darja Husejnagić
Faculty of Natural Sciences and Mathematics, University of Tuzla, Urfeta Vejzagića 4, 75 000 Tuzla, B&H

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Spectral Analysis and In Vitro Biological Activity of Cu(II) Complex with Tridentate ONO Schiff Base Ligand Emir Horozić; Merima Ibišević; Darja Husejnagić; Enida Karić; Nusreta Hasić; Amina Hajdarević
The Journal of Pure and Applied Chemistry Research Vol 10, No 2 (2021): Edition May-August 2021
Publisher : Chemistry Department, The University of Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jpacr.2021.010.02.569

Abstract

In this study, metal complex of Copper(II) with a Schiff base derived from 2,2-dihydroxyindane-1,3-dione and 2-aminoethanoic acid were synthesized. The product are characterized by spectral methods. The antimicrobial activity was tested on reference bacterial strains and the antioxidant capacity was analyzed by using the DPPH and FRAP methods. The spectral data indicates that the Schiff base coordinates the Copper(II) as a tridentate ONO donor ligand. The compounds showed weaker antimicrobial activity on certain tested microorganisms. In vitro testing of antioxidant activity showed a significant reducing ability of the complex, as well as inhibitory activity against DPPH radicals.