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All Journal Damianus Journal of Medicine Ophthalmologica Indonesiana
Anthea Casey
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Health Professions Medicine & Pharmacology Public Health

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Journal : Ophthalmologica Indonesiana

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BILATERAL SEROUS RETINAL DETACHMENT AS OCULAR MANIFESTATION IN ACUTE LYMPHOBLASTIC LEUKEMIA: A CASE REPORT: Poster Presentation - Case Report - General practitioner Anthea Casey; Dian Estu Yulia
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/tb4c3853

Abstract

Introduction : Acute lymphoblastic leukemia (ALL) is known to cause several ocular involvements. However, retinal detachment is a rare complication. This report aims to present unusual ocular manifestations in the form of bilateral serous retinal detachment in a pediatric patient. Case Illustration : An 11-year-old girl with a diagnosis of relapsed ALL and thrombocytopenia was referred to the Ophthalmology Department due to sudden blurred vision. The patient was undergoing chemotherapy on the third cycle due to the relapse. Visual acuity was 1/300 in both eyes. Fundus examination showed bilateral serous retinal detachment. No treatment in ophthalmology was given due to the unstable condition of this patient. Discussion : Up to 90% of all leukemia patients have fundus changes during the disease. The presence of unilateral or bilateral serous retinal detachment as a sign of choroidal infiltration may be one of the manifestations of acute leukemia, both as a primary sign and a relapse. Literature has shown that chemotherapy, radiation, and systemic prednisone would improve the visual acuity in these patients. However, in this case, when the patient is unstable and experiencing a series of complications, we decided that life-saving treatment comes first. Conclusion : The incidence of ocular involvements in ALL could be due to the treatment and the disease itself. Prompt recognition of disease led to early systemic treatment and restoration of visual function. The goal of sight-saving comes second after life-saving treatments.
EFFECT OF CAFFEINE CONSUMPTION ON INTRAOCULAR PRESSURE AND RISK OF GLAUCOMA: A SYSTEMATIC REVIEW Paramitha, Dewa Ayu Anggi; Azhari, Fierda Ovita; Anthea Casey; Eldinia, Lourisa Ruth
Majalah Oftalmologi Indonesia Vol 50 No 2 (2024): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v50i2.100985

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INTRODUCTION AND OBJECTIVES Glaucoma is one of the leading causes of blindness worldwide with intraocular pressure (IOP) as its main risk factor. Several studies have investigated the association between IOP and caffeine consumption with mixed results. This study aims to review whether caffeine consumption increases IOP thus, increases the risk of glaucoma. METHODS A comprehensive literature search was performed in 4 databases, including Pubmed, Proquest, ScienceDirect, and Cochrane. Last search was conducted on March 20, 2023. We include human studies investigating caffeine impact on IOP and/or glaucoma risk published in English with full text available from 2013 to 2023. The risk of bias was assessed with RoB 2.0 for crossover studies, NIH for cross-sectional and case-control studies. We present our results according to PRISMA guidelines. RESULT A total of 130.012 participants from 7 different studies were included in this review. Three crossover, 3 cross-sectional, and 1 case-control study were evaluated. This study involved a multi-racial population although Caucasian predominated. Five out of 7 studies exhibited a significant association (all p values <0.05) between caffeine consumption and increased risk of developing glaucoma. CONCLUSION Caffeine consumption generally shows a significant impact on developing risk of glaucoma and has been shown to increase IOP in acute settings, reported up to 90 minutes after consumption/ingestion. Limitations of this study include a small number of crossover participants and a high variability of participants (young healthy individuals and glaucoma patients). Further research is advised to investigate the association between caffeine consumption in a longer follow-up time and a more specific population.
Co-Authors Azhari, Fierda Ovita Dharmady Agus Eldinia, Lourisa Ruth Eva Suryani Herlina Uinarni Paramitha, Dewa Ayu Anggi