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All Journal ODONTO Dental Journal Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Odonto dental journal Jurnal Pengabdian Masyarakat Dentmas
Recita Indraswary
Fakultas Kedokteran Gigi, Universitas Islam Sultan Agung (UNISSULA)
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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EFEK COENZYME Q10 TERHADAP SEL NEUTROFIL DAN SEL MAKROFAG PADA MODEL TIKUS PULPITIS Nurhapsari, Arlina; Kusuma, Andina Rizkia P; Indraswary, Recita; Widyasari, Ferina; Rahma, Destari Amelia
Syifa'Medika Vol 12, No 1 (2021): Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan
Publisher : Faculty of Medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/sm.v12i1.3296

Abstract

Pulpitis akut merupakan penyakit peradangan pulpa dengan prevalensi yang tinggi di Indonesia. Pada proses peradangan awal sel yang paling banyak berperan adalah sel neutrophil dan makrofag. Proses inflamasi tidak terlepas dari peran Reactive Oxygen Species (ROS). Reactive Oxygen Species dapat diturunkan kadarnya dengan pemberian antioksidan. Coenzyme Q10 merupakan salah satu antioksidan alami dengan kandungan Ubiquinone, bahan ini belum banyak diteliti penggunaannya di bidang kedokteran gigi. Penelitian ini bertujuan mengetahui pengaruh pemberian Coenzyme Q10 terhadap jumlah sel neutrofil dan sel makrofag pada gigi maksila tikus yang mengalami pulpitis. Jenis penelitian ini adalah experimental laboratorium in vivo. Model pulpitis diinduksi pada 15 tikus Sprague Dawley jantan dengan membuka pulpa gigi maksila pertama. Tikus dibagi menjadi tiga kelompok yaitu kelompok A1 (Coenzyme Q10); A2 (eugenol) dan A3 (akuades). Gigi maksila diambil setelah hari ke-3 dan dilakukan pemeriksaan histologi. Hasil uji Kruskal Wallis menunjukkan perbedaan signifikan antara ketiga kelompok tersebut. Pada uji Mann Whitney menunjukkan tidak ada perbedaan signifikan pada kel A1 dan A2. Kesimpulan dari penelitian ini adalah Coenzyme Q10 mempunyai kemampuan yang sama dengan eugenol dalam menurunkan jumlah sel inflamasi.
UPAYA PENCEGAHAN MALNUTRISI ANAK MELALUI VIDEO EDUKASI PENGELOLAAN KARIES GIGI Amalina, Rizki; Indraswary, Recita; Istiqomah, Istiqomah
Jurnal Pengabdian Masyarakat DentMas Vol 1, No 2 (2023): DESEMBER 2023
Publisher : Faculty of Dentistry Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/dentmas.1.2.72-76

Abstract

Background: Malnutrition problem in Indonesia is still a challenge in order to improve the quality generation of Indonesian in the future. Reflecting on the 2018 Basic Health Research (Riskesdas), the prevalence of malnutrition in children in Indonesia reached 17.7 percent. One of the reasons is the increased consumption of sweet and sticky foods and drinks. The presence of children's caries can also cause psychological disturbances and pain so children have difficulty chewing food and getting inadequate nutrition. There is a need for earlier intervention through education on the need for caries management to prevent child malnutrition. This program was held to provide educational videos on caries management as an early intervention effort to prevent malnutrition in children.Method : The implementation of community service was carried out in several stages, namely: location survey, licensing, making educational videos, implementing education in the form of outreach to community cadres and preparing activity reports. Education is carried out by counselling using video media to community cadres including delivery of material, discussion (questions and answers) with resource persons and ending with conclusions and follow-up planning for implementation in the family environment.Result: The knowledge of cadre increasing because educational video can provide audio and visual illustration. Conclusion: Educational videos on caries management can be an alternative as an early intervention effort to prevent malnutrition in children.
Chana striata Albumin Gel Accelerate Post tooth extraction Wounds Healing on Hyperglycemic Rats Indraswary, Recita; Muchaeroni, Isa Anshori; Ardlina, Nira; Amrullah, Alex
Odonto : Dental Journal Vol 11, No 1 (2024): July 2024
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.11.1.88-93

Abstract

Background: Hyperglicemic patients with type 2 diabetes often experience slow wound healing due to poor neovascularization, macrophages and fibroblast, therefore, medicine is needed to speed up the wound healing process, one of which is albumin. Albumin is a protein that has been shown to have antioxidant properties and also plays a role in accelerating the inflammatory process and stimulating the growth of new cells.Method: This research used laboratory experiments and a Post Test Only Control Group Design research design. The number of research samples used was 26 wistar rats, snakehead fish albumin gel extract is made by maceration and gelled using CMC (Carboxyl methyl cellulose), assessment method by observing fibroblasts, neovasculature and macrophages which are visible in Hematoxylin Eosin and toluidine blue staining.Result: The results of the research showed that the group that was given snakehead fish albumin extract gel had a higher average number of neovascular, macrophage and fibroblast values than the group that was not given snakehead fish albumin extract gel. The Mann Whitney test and Independent Sample T-Test showed that there were significant differences between the 2 groups.Conclusion: The conclussion from this research is there is an effect of gived snakehead fish albumin gel on tooth extraction wounds in Diabetes Mellitus rats
Chana striata Albumin Gel Accelerate Post tooth extraction Wounds Healing on Hyperglycemic Rats Indraswary, Recita; Muchaeroni, Isa Anshori; Ardlina, Nira; Amrullah, Alex
Odonto : Dental Journal Vol 11, No 1 (2024): July 2024
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.11.1.88-93

Abstract

Background: Hyperglicemic patients with type 2 diabetes often experience slow wound healing due to poor neovascularization, macrophages and fibroblast, therefore, medicine is needed to speed up the wound healing process, one of which is albumin. Albumin is a protein that has been shown to have antioxidant properties and also plays a role in accelerating the inflammatory process and stimulating the growth of new cells.Method: This research used laboratory experiments and a Post Test Only Control Group Design research design. The number of research samples used was 26 wistar rats, snakehead fish albumin gel extract is made by maceration and gelled using CMC (Carboxyl methyl cellulose), assessment method by observing fibroblasts, neovasculature and macrophages which are visible in Hematoxylin Eosin and toluidine blue staining.Result: The results of the research showed that the group that was given snakehead fish albumin extract gel had a higher average number of neovascular, macrophage and fibroblast values than the group that was not given snakehead fish albumin extract gel. The Mann Whitney test and Independent Sample T-Test showed that there were significant differences between the 2 groups.Conclusion: The conclussion from this research is there is an effect of gived snakehead fish albumin gel on tooth extraction wounds in Diabetes Mellitus rats
Co-Authors Amrullah, Alex Arlina Nurhapsari istiqomah istiqomah Kusuma, Andina Rizkia P Muchaeroni, Isa Anshori Nira Ardlina, Nira Rahma, Destari Amelia Rizki Amalina Widyasari, Ferina