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All Journal Majalah Ilmiah Sultan Agung e-GIGI Medali Jurnal : Media Dental Intelektual ODONTO Dental Journal Insisiva Dental Journal : Majalah Kedokteran Gigi Insisiva Dentino: Jurnal Kedokteran Gigi Padjadjaran Journal of Dentistry Gemakes: Jurnal Pengabdian Kepada Masyarakat Denta: Jurnal Kedokteran Gigi Cakradonya Dental Journal Odonto dental journal Jurnal Pengabdian Masyarakat Dentmas Karya Kesehatan Journal of Community Engagement
Rizki Amalina
Departement Oral Biology. Universitas Islam Sultan Agung.
Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Pembentukan Mikronukleus di Mukosa Bukal akibat Paparan Senyawa Kimia pada Berbagai Macam Pekerjaan Setiabudi, Deny; Amalina, Rizki; Feranisa, Anggun
e-GiGi Vol 9, No 1 (2021): E-GiGi
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/eg.9.1.2021.32711

Abstract

Abstract: In general, an occupation could have hazzard and risk of exposure to genotoxic chemical compounds. These compounds could lead to micronucleus formation on buccal mucosa. This study was aimed to obtain the impact of chemical exposure on micronucleus formation in buccal mucosa at various occupations. This was a literature review study using databases of PubMed, ScienceDirect, and Google Scholar based on the keywords. The criteria of literatures were articles published in 2016-2021 using Indonesian or English language. The results showed that  group compounds of polycyclic aromatic hydrocarbons (PAH), metals, carbamate, and organophospate, also compunds of silica, bezene, toluene, xylene (BTX), sevoflurane, desflurane, isoflurane, nitrous oxide, gemcitabin, and 5-fluoro uracil were genotoxic chemical compunds and could cause micronucleus formation in buccal mucosa of mechanics, grillers, miners, e-waste recyclers, construction workers, road markers, car painters, gasoline station workers, farmers, and healthcare workers. Genotoxic chemical compounds could be found excessively in occupational environment. These compounds could damage cells’ DNA and caused micronucleus formation on buccal mucosa of workers. It is suggested to study further about cell damage biomarkers caused by genotoxic chemical compound exposure.Keywords: micronucleus formation in buccal mucosa, chemical exposure of genotoxic compounds, occupational riskAbstrak: Suatu pekerjaan dapat memiliki risiko dan bahaya terpapar senyawa kimia yang bersifat genotoksik. Senyawa kimia tersebut dapat menyebabkan terbentuknya mikronukleus di mukosa pipi rongga mulut. Penelitian ini bertujuan untuk mengulas pengaruh paparan senyawa kimia pada berbagai macam pekerjaan terhadap pembentukan mikronukleus di mukosa bukal. Jenis penelitian ialah literature review. Penelusuran literatur melalui database PubMed, ScienceDirect, dan Google Scholar berdasarkan kata kunci yang sesuai. Kriteria literatur ialah terbitan tahun 2016-2021 dengan Bahasa Indonesia atau Inggris. Hasil penelitian mendapatkan senyawa kelompok polycyclic aromatic hydrocarbon (PAH), logam, carbamate, dan organophospate, serta senyawa silica, benzene, toluene, xylene (BTX), sevoflurane, desflurane, isoflurane, nitrous oksida, gemcitabin, dan 5-fluoro uracil merupakan senyawa kimia yang bersifat genotoksik dan dapat memicu pembentukan mikronukleus di mukosa bukal mekanik, pemanggang daging, penambang, pendaur ulang sampah elektronik, pekerja konstruksi, pekerja marka jalan, pengecat mobil, petugas SPBU, petani dan tenaga kesehatan. Senyawa kimia yang bersifat genotoksik banyak ditemukan di lingkungan pekerjaan. Senyawa tersebut dapat merusak DNA sel sehingga terbentuk mikronukleus di mukosa bukal pekerja. Disarankan untuk melakukan penelitian lanjut mengenai biomarker kerusakan sel akibat paparan senyawa kimia yang genotoksik.Kata kunci: pembentukan mikronukleus di mukosa pipi, paparan senyawa kimia genotoksik, risiko pekerjaan
HUBUNGAN IBU PEROKOK PASIF SEBAGAI FAKTOR LINGKUNGAN TERHADAP KEJADIAN CELAH BIBIR DENGAN ATAU TANPA CELAH PALATUM NONSINDROMIK (Pada Pasien RSI Sultan Agung Semarang Bulan Juni 2012) Beti Ratnasari; Rizki Amalina; Yayun Siti Rochmah; Arlina Nurhapsari
Jurnal Medali Vol 1, No 1 (2013): Media Dental Intelektual
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.v1i1.76

Abstract

Nonsyndromic cleft lip with or wihout cleft palate (CL±CP) is a congenital defect caused by genetic and environmental factors. One of the its environmental factors is passive smoking mother. The increasing risk of CL±CP in passive smoking mothers occurs due to the fetal hypoxia caused by carbon monoxide and nicotine in cigarette smoke. The aim of this study is to determine the relationship of passive smoking mothers as environmental factor towards the incidence of nonsyndromic CL±CP in patients of Sultan Agung Islamic Hospital Semarang June 2012.This study used cross sectional method. The samples were 16 CL±CP patients at Sultan Agung Islamic Hospital Semarang June 2012 with their mothers who had fulfilled exclusion and inclusion criteria stated in the questionnaire and 16 control subjects. The motherswere qualified as passive smokers if they met all requirements. The data analysis involved Chi-square test as descriptiveand hypothesis test.The analysis results showed significant relationship (p<0,05) with prevalence ratio (RP)=2,647 and confidence interval (CI) 95%=1,083-6,469. Twelve out of sixteen CB±CP patients’ mothers were passive smokers.  In conclusion, there is a relationship between passive smoking mothers as environmental factor towards the incidence of nonsyndromic CL±CP in patients of Sultan Agung Islamic Hospital Semarang June 2012.Keywords: passive smoking mothers, cleft lip, cleft lip with cleft palate, nonsyndromic, carbon monoxide, nicotine, hypoxia
HUBUNGAN ANTARA PERILAKU IBU RUMAH TANGGA TERHADAP STATUS KARIES GIGI ANAK PRASEKOLAH DI KELURAHAN PEDURUNGAN TENGAH KECAMATAN PEDURUNGAN KOTA SEMARANG Armitha Hapsari; Sandy Christiono; Rizki Amalina; Rama Putranto
Jurnal Medali Vol 1, No 1 (2013): Media Dental Intelektual
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.v1i1.87

Abstract

Dental caries is a dental hard tissue disease that often occurs especially in preschool children. One of the many factors cause dental caries in preschool children is the role of mother. The importance of housewife role which was emulated by their children particularly dental health can the level of children caries. The aim of this study is to determine the relationship of housewife behavior towards dental caries status of preschool children in the Kelurahan Pedurungan Kecamatan Pedurungan Tengah of Semarang.This research used analytic methods with cross-sectional observational study. The subject of this research was preschool children in kindergarten Tunas Kekancan Mukti and Islamic kindergarten Berlian totaling 82 childrens and 82 mothers. Data collection was obtained through examination of caries teeth of children and housewives behavior was obtained by using questionnaires that its validity has been tested, and then processed. Data analysis includes descriptive analysis and hypothesis test using Pearson Product Moment Correlation test.The result showed that 31,7% houswives belongs to bad behavior score criterion, 43,9% belongs to moderate behavior score criterion and 24,4% belongs to good behavior score criterion. The average housewives behavior is sufficient criteria. Because the data was not normal, the Spearman Rho test was used and found that there is a correlation between housewives behavior towards caries of preschool children. Data analysis of the relationship was not normal so used Spearman Rho test.The result of this research can be conclude that there is a relation between housewives behavior towards caries preschool children in the Kelurahan Pedurungan Kecamatan Pedurungan Tengah of Semarang. Keywords : housewife behavior, dental caries preschool childrens, caries status of preschool children
LITERATURE REVIEW : CHARACTERISTIC ANALYSIS PHYSICAL CHEMISTRY PROPERTIES (ACIDITY, FLOW RATE, CONSISTENCY) SALIVA RADIOTHERAPY HEAD & NECK CANCER PATIENT Muhammad Henri Indrawan; Rizki Amalina; Febia Astiawati Sugiarto
Jurnal Medali Vol 3, No 1 (2021): Media Dental Intelektual September 2021
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.v3i1.17166

Abstract

Background: Head and Neck Cancer (oral, nose, pharynx, and larynx area) are 890.000 new cases and 450.000 deaths in 2018. One of the treatment’s Radiotherapy affects saliva’s quality in physicochemical properties (flow rate, consistency, and acidity). Physicochemical properties are analyzed because they can influence saliva’s quality. The study is to get updated analysis about physicochemical properties’ saliva in Radiotherapy of Head and Neck Cancer Patient. Method: There are 39.972 articles, searched in Google Scholar, Academia, and Microsoft Academy database. The articles that are connected with keywords topic are 52 articles with abstract and title screening processes. The next process is selecting articles and getting 17 excluding articles and 35 including articles. The total articles are 35 articles. Therefore, they’re ready to be analyzed.Result: Major result of the analysis is radiotherapy affecting patients with Xerostomia. There’s a reducing flow rate, increasing consistency, and pH decrease in the acute phase. In the late phase, physicochemical properties’ saliva quality is decreased because of high ionizing radiation damaging DNA and membrane of the acinar cell. Primary saliva became hypertonic because protein kinase A enzyme and protein kinase C enzyme fail to do phosphorylation to build protein materials in the acinar cell. Conclusion: Radiotherapy making Xerostomia impact decreasing physicochemical properties’ quality in head and neck cancer. Education is the main thing to take Xerostomia’s complications for maintaining OHI like teeth brushing, chlorhexidine, fluoride or salivary stimulant application, and others. Analysis can be developed for the observation of consistency outcomes based on quantity.
IMPROVEMENT OF DENTAL AND ORAL HEALTH BY CADERIZATION OF JUNIOR DENTISTS Sandy Christiono; Rizki Amalina; Prima Agusmawanti
Jurnal Medali Vol 4, No 1 (2022): Media Dental Intelektual March 2022
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.4.1.83-90

Abstract

Background: Dental caries is still an unresolved problem. One method for the prevention of dental caries is the counselling method. Caderization is a long-term educational process for optimizing the potential of cadres by transferring and instilling specific values so that later it will produce strong cadres. Junior dentists meet the criteria and have been trained to participate in efforts to maintain and improve health for themselves, friends, family and the environment. The purpose of a junior dentist is to become drivers of healthy living at school, at home, and in their environment to help themselves, fellow students and others live healthy lives. Method: Making counselling media consisting of posters for counselling, models of teeth and toothbrushes, counselling videos about dental health delivered by junior dentists and conducting questionnaires for students' understanding levels. Data analyzed using descriptive statisticsResult: The results of the research in filling out the questionnaire after the students saw and listened to the junior dentist educational video found that 81.3% brushed their teeth twice a day, 59.4% answered that sweet foods caused cavities, 71.9% responded correctly that cavities if not treated will cause swelling, 90.6% answered incorrectly that teeth were only left alone if they had cavities and 93.8% answered how to maintain oral hygiene by brushing their teeth properlyConclusion: There is an increased understanding of dental and oral health
PERBEDAAN JUMLAH ACTINOBACILLUS ACTINOMYCETEMCOMITANS PADA PERIODONTITIS AGRESIF BERDASARKAN JENIS KELAMIN Rizki Amalina
Majalah Ilmiah Sultan Agung Vol 49, No 124 (2011): Jurnal Majalah Ilmiah Sultan Agung, Juli 2011 (Edisi Khusus FKG)
Publisher : Majalah Ilmiah Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Prevalence of aggressive periodontitis showing the tendency to increase annually. Actinobacillus actinomycetemcomitans, is primary caused aggressive periodontitis, a pathogen not only in periodontal but also in some nonoral infections, possesses several virulence determinants which contribute to its ability to colonize the oral cavity, persist in the periodontal pocket, resist and evade host defenses, cause destruction to soft and hard tooth-supporting tissues, and interfere with host tissue repair after infection. This study is a cross sectionalstudy. Actinobacillus actinomycetemcomitans cultivated in AaGMBV dan measured by colony counter. The main sex hormones exerting influence on the periodontium are estrogen and progesterone. In women, during puberty, ovulation and pregnancy, there is an increase in the production of sex steroid hormones characterized by gingival enlargement, increased gingival bleeding andcrevicular fluid flow and microbial changes. The result of this study statistically analyzed by independent t-test because the member of each group totally separated. The analysis showed the value of p<0,05. It means that there are quantity differences between male and female. Keywords: Aggressive Periodontitis, Actinobacillus actinomycetemcomitans quantity, sex hormones
HUBUNGAN KADAR UREA SALIVA TERHADAP DERAJAT KEASAMAN (pH) SALIVA PADA ANAK USIA 12-15 TAHUN Nifarea Anlila Vesthi; Grahita Aditya; Rizki Amalina
ODONTO : Dental Journal Vol 2, No 2 (2015): December 2015
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.2.2.57-61

Abstract

Introduction: One of the dental disease in the oral cavity that often experience by society are caries. Caries is one of the hard tooth tissue disease that can touch enamel, dentin, and sementum. One of the factor that affect caries process is saliva. Urea is one of the organic composition that compose saliva. Urea in salive plays as buffer capacity and the pH saliva adjustment.Methods: This study is an analytic observational with cross sectional approach, this study are conducted in Daarul 'Ilmi Islamic boarding school with 19 subject of 12-15 years old child. The data are obtained from the examination of urea saliva level and pH saliva in child. The level of urea saliva are measured using spectrophotometer tools and the pH saliva are measured using pH meter. The Shapiro-wilkare used to deterime the data normality, continue with Leuvenetest to determinde the data homogeneity data. Data are analyzed using Pearson test to determine the relation of urea level in saliva against the pH saliva.Results: According the data analysis, the data are in normal distribution and homogeneous. The research result are obtain average of urea level in urea sample is 13,45 mg/dl, and the average of pH saliva sampelis 7,15. The result of Pearsonstatistic testare obtain p value of = 0,000, with the positive correlation level of 0,902.Conclusion: The conclusion of this study are note that there are relation between the urea level in saliva against pH salive. This are proven from the Pearson test result with significance value of 0.000 (p< 0.05).
PENGARUH EKSTRAK DAUN BELUNTAS (Pluchea indica (L.) Less) 25% TERHADAP BIOFILM STREPTOCOCCUS MUTANS - in vitro Clarissa Bonita Syaravina; Rizki Amalina; Eko Hadianto
ODONTO : Dental Journal Vol 5, No 1 (2018): July 2018
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.5.1.28-33

Abstract

Background: Bioflm begins with formation of pelicle and within a minutes the colonization of bacteria attached to surface of the teeth. One of early bacteria attached was Streptococcus mutans. This study used 25% beluntas leaf extract in influencing the growth of Streptococcus mutans bioflm. The purpose of study was to investigated effect of 25% beluntas leaf extract on Streptococcus mutans bioflm.Methods: This research was experimental laboratory with post test only control design, consist of four treatment groups, 25% beluntas leaf extract and 0.12% chlorhexidine incubated 24 hours and 48 hours. Bioflm formation was measured by calculating Optical Density using a spectrophotometer. Data analysis was performed using One Way Anova test followed by Post Hoc LSD test.Result: The results showed that beluntas leaf extract could influence theformation of S.mutans bioflm but the effect in inhibiting bioflm formation is still not as good as chlorhexidine. It is known from the results of One Way Anova 25% beluntas leaf extract and 0.12% chlorhexidine incubated for 24 hours and 48 hours showed signifcant difference (p <0.05).Conclusion: The conclusion of this research is the effect of beluntas leaf extract (Pluchea indica (L.) Less) 25% to Streptococcus mutans bioflm in vitro.
PENGARUH KEHILANGAN GIGI POSTERIOR TERHADAP KUALITAS HIDUP INDIVIDU LANJUT USIA STUDI TERHADAP INDIVIDU LANJUT USIA DI UNIT REHABILITASI SOSIAL PUCANG GADING DAN PANTI WREDHA HARAPAN IBU SEMARANG Gilang Satria Wardhana; Moh. Baehaqi; Rizki Amalina
ODONTO : Dental Journal Vol 2, No 1 (2015): July 2015
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.2.1.40-45

Abstract

Background: Elderly is an individual who has reached the age of 60 years and above. The aging process causes changes in the physical condition of the individual and affect the structure of the oral cavity includes the function of teeth, jaws and other oral tissues. Loss of teeth leads to reduced ability to chew, bite, talk and decrease a person's confidence. Quality of life is the individual response to physical function, psychological and social to their everyday lives. Oral Health Related Quality of Life can be measured by several kinds of questionnaires, one of them is OHIP - 14. Purpose: The aim of this study are to determine impact of losing posterior teeth on quality of life on elderly individuals between tooth loss <3 posterior teeth with tooth loss <3 posterior teeth in an arch. Method: The research method was analytic observational cross-sectional approach. The sample in this study were 40 individuals who were divided into two groups, group A elderly individuals with posterior tooth loss < 3 in one arch and group B elderly individuals with posterior tooth loss < 3 in one arch. Analysis of the data in this study was using a non-parametric test with Kolmogorov -Smirnov test with p < 0.05. Result: Based on the Kolmogorov -Smirnov test , concluded there are significant differences between groups A and group B ( p < 0.05 ). Conclusion: From the results of this study concluded that elderly individuals with posterior tooth loss < 3 in the arch have a better quality of life. Group b elderly individuals with posterior tooth loss ≥ 3 in the arch have a lower quality of life.
ANALYSIS OF SULFUR VAPOR EXPOSURE TO THE NUMBER OF MICRONUCLEUS AND ORAL BUCCAL EPITHELIAL MORPHOLOGY Rizki Amalina; Aulia Rohmania; Anggun Feranisa
Dentino : Jurnal Kedokteran Gigi Vol 5, No 1 (2020)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v5i1.8130

Abstract

Background: The sulfur vapor consists of  SO2 and CO2 which are genotoxins that may cause the damage of DNA to the micronucleus in buccal epithelial cells. Micronucleus is a mass like a nucleus, measuring one-third of the nucleus. DNA damage can also be seen from changes in the morphology of epithelial cells. Objective: This study aimed to identify the effect of sulfur vapor exposure on the number of micronucleus and morphology epithelial cells in the oral cavity on the sulfur miner. Methods: The method of this study was analytic observational with a cross-sectional approach. The total sample of this study was 24  respondents divided into 2 groups, each group contained 12 respondents. Exfoliated buccal cells were collected by scrapping the buccal mucosa. The specimens stained using Hematoxylin and Eosin. Nucleus and cytoplasmic area were examined using image J 1.40 Results: The result showed the average number of buccal mucosa micronucleus on coal miners higher (35,50) than controls (11,58). The result of Independent-measures T-test obtained significant different on the number of micronucleus between sulfur miner and controls (p=0,000). The result of Independent-measures T-test on the nuclear area and cytoplasmic area between sulfur miner and controls obtained insignificant different (p=0,379 dan p=0,616). Conclusion: Based on this study can be concluded that sulfur vapor exposure affected on the number of micronucleus on sulfur miners, but did not influence morphology of epithelial cells.
Co-Authors Algamar, Danty Anggun Feranisa Arif Firmansyah Arlina Nurhapsari Armitha Hapsari Aulia Rohmania Avena Dwi Kunfiar Beti Ratnasari Clarissa Bonita Syaravina Dewi Monica Eko Hadianto Febia Astiawati Sugiarto Firda Yanuar Syafaat Gilang Satria Wardhana Grahita Aditya Grahita Aditya Hafisza Syalsyabila Maghfira Indriastanti, Rikha Islamy Rahma Hutami, Islamy Rahma istiqomah istiqomah Layyinatus Syifa, Liftia Mahdalena Mahdalena Moh. Baehaqi Muchaeroni, Isa Anshori Muhammad Henri Indrawan Nabila Rizkika, Nabila Nagita Dari Karini Naila Salsabila Nifarea Anlila Vesthi Nur Istighfah, Jafifah Mega Prima Agusmawanti, Prima Rahmat Hidayat Rahmawati Sri Praptingingsih Rahmawati Sri Praptiningsih Rama Putranto Recita Indraswary Recita Indraswary Rina Kartika Sari Rohmah, Yayun Siti Sandy Christiono Sari, Mona Seno Pradopo Setiabudi, Deny Welly Anggarani Welly Anggarani, Welly Yayun Siti Rochmah Yuniar, Savira Nurazky Yunita Styaningrum Yusril Yusuf