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Perbedaan Tingkat Pengetahuan Pencegahan Kanker Serviks SMA Negeri dan Swasta Kelas X Kabupaten Badung : knowledge level on cervical cancer prevention among class X high school female students in public versus the private schools within the Badung Regency. Made Intan Ryani Putri; Ni Wayan Armerinayanti; Ni Luh Putu Eka Kartika Sari
Aesculapius Medical Journal Vol 2 No 1 (2022): Juni
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.2.1.2022.8-12

Abstract

The average age for first having sexual intercourse outside of marriage, which is 14-19 years, is one of the causes of the risk of cervical cancer. This research compares the knowledge level on cervical cancer prevention among class X high school female students in public versus the private schools within the Badung Regency. A cross-sectional comparative study is used as the study designed, which includes a total sample of 336 female students (n=336) by utilizing questionnaires. Bivariate analysis with Interdependent T-test and Statistical Package for Social Sciences (SPPS) is appropriate for analyzing the gathered research data. The results of this study between public and private high schools in Badung Regency have different levels of knowledge about cervical cancer prevention. Data analysis shows that 99 (29.5%) female respondents in public high schools know about cervical cancer prevention, and only 80 (23.8%) female students from private schools. The findings of this study imply that school-based teaching is critical for increasing understanding and lowering cervical cancer rates, as well as collaborating with the health department to provide cervical cancer counseling and installing health-related information media in the school environment.
Goiter Sebagai Faktor Predisposisi Karsinoma Tiroid Ni Wayan Armerinayanti
WMJ (Warmadewa Medical Journal) Vol 1 No 2 (2016): November 2016
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.1.2.27.42-50

Abstract

Goiter merupakan pembesaran kelenjar tiroid yang dapat berkaitan dengan gangguan primer pada organ tiroid ataupun akibat stimulasi hormonal atau faktor lain terhadap tiroid. Di Indonesia dan di Bali khususnya kasus karsinoma tiroid mengalami peningkatan sejalan dengan peningkatan kasus goiter endemik maupun non endemik. Goiter memiliki faktor risiko sebesar 2,5 kali lipat untuk menimbulkan karsinoma tiroid. Goiter dapat menimbulkan hiperplasia yang bersifat difusa maupun noduler (nodul tunggal dan multipel). Analisis klonal telah membuktikan bahwa hiperplasia merupakan proliferasi yang bersifat poliklonal. Pada tiroid, ditemukan perubahan pola monoklonal pada kelompok nodul yang sebelumnya merupakan nodul hiperplastik. Perubahan poliklonal menjadi monoklonal ini merupakan interaksi antara adanya lesi hiperplastik sebelumnya dengan predisposisi genetik yang selanjutnya menciptakan lingkungan mutagenik, ditandai oleh peningkatan proliferasi sel disertai pembentukan radikal bebas yang memicu adanya mutasi somatiktirosit. Pemberian suplementasi iodium pada kasus goiter endemik, dikatakan berkaitan dengan adanya kandungan iodine radioaktif nantinya justru menimbulkan kerusakan rantai DNA melalui tata ulang RET-TRK.Kata Kunci: goiter, predisposisi, karsinoma tiroid. [Goitre as Predisposing Factor of Thyroid Carcinomas].Goitre is an enlargement of thyroid gland which can be associated with primary thyroid disorders or stimulation of the gland by hormones and other factors. In Indonesia and especially in Bali, increase of Thyroid Carcinoma cases had been associated with either endemic or non endemic goiter. Goitre increases 2.5 fold risk of thyroid carcinoma. Goitre may cause diffuse and nodular hyperplasia (either single or multiple nodules). Clonal analysis has been discovered that hyperplasia is considered to be polyclonal proliferation. Monoclonal alterations had also been found in a subset of thyroid nodules that were previously considered hyperplastic. Alterations of polyclonal to monoclonal pattern was considered as interaction between past history of hyperplastic lesion and genetic predisposition which furthermore forming mutagenic environment such as increases of cell proliferation and also free radicals induce- somatic mutation. Iodine supplementation on endemic goiter related with radioactive iodine content which damaging DNA sequences in the form of RET-TRK rearrangement.Keywords: goitre, predispose, thyroid carcinoma.
Karakteristik Pasien Pasca-Apendektomi di Rumah Sakit Umum Daerah Tabanan I Komang Ardhika Gunawan; Ni Putu Diah Witari; Ni Wayan Rusni; Ni Wayan Armerinayanti; Gde Candra Yogiswara; Ade Dwi Mahendra; I Gusti Ngurah Fajar Viwakananda; Made Bramastya Nugraha Teja Kusuma Mulyawan
Jurnal Ilmiah Kedokteran dan Kesehatan Vol. 5 No. 2 (2026): Mei: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v5i2.6473

Abstract

Acute appendicitis is one of the most common abdominal surgical emergencies, primarily managed through appendectomy. Post-appendectomy patients require further hospitalization, where indicators such as length of stay, leukocyte levels, and pain intensity are essential to evaluate clinical outcomes. This study aims to describe the characteristics of post-appendectomy patients at Tabanan General Hospital (BRSU Tabanan) in 2023–2024. This research used a descriptive observational design with a cross-sectional approach, and data were collected retrospectively from medical records. Samples were selected using consecutive sampling, with a total of 120 patients who met the inclusion and exclusion criteria. Data were analyzed univariately and presented in frequency distributions and mean values.The results showed that the mean age of patients was 34.73 ± 13.62 years, with a higher proportion of females (56.7%) compared to males (43.3%). The mean leukocyte count was 12.65 ± 4.22 ×10³/µL, with most patients (56.7%) categorized as mild leukocytosis. The mean length of stay was 2.83 ± 1.54 days, with 93.3% of patients classified as having a short hospitalization period (≤5 days). Most patients had no comorbidities (85%), while hypertension was the most common comorbid disease (61.1%). The mean Visual Analog Scale (VAS) score before appendectomy was 5.34 ± 0.96 (moderate pain), which decreased to 2.42 ± 0.63 (mild pain) after surgery.