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All Journal EKSAKTA: Journal of Sciences and Data Analysis Majalah Ilmiah Biologi BIOSFERA: A Scientific Journal Jurnal Serambi Abdimas
Hartiwi Diastuti
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Earth & Planetary Sciences Environmental Science Materials Science & Nanotechnology

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PEMURNIAN, IDENTIFIKASI DAN UJI AKTIVITAS ANTIDIABETES SENYAWA METABOLIT SEKUNDER EKSTRAK ETIL ASETAT DAUN KACA PIRING (Gardenia augusta, Merr) Chasani Mochamad; Hartiwi Diastuti; Rizka Aprilia
EKSAKTA: Journal of Sciences and Data Analysis VOLUME 12, ISSUE 2, August 2011
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

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Abstract

Gardenia augusta, Merr is one of the family Rubiaceae species used as traditional medicine because it has medicinal properties, such as drug diabetes mellitus. These research have been done on this plant, among others, is the ability of the extract and the active fraction ethyl acetate extract of Gardenia augusta, Merr leaves to lowering blood sugar levels of rats. The purpose of this research was to purification of the active fraction of the ethyl acetate extract and identify the secondary metabolites of Gardenia augusta, Merr leaves as well as test that can be used antidiabetic. Purification was done by column chromatography which was eluted with n-hexane: ethyl acetate (7:1) and obtained four groups of fractions. The fractions of the TLC to obtain pure isolates F2 fraction with melting point 158-160 ° C. The antidiabetic activity of the isolate F2 fractions were tested into white rats by glucose tolerance methods. Isolate F2 fraction was identified by using UV and IR spectrophotometer. The results showed that isolate F2 fraction of ethyl acetate extract of Gardenia augusta, Merr leaves has a hypoglycemic effect of 21.05%. The secondary metabolites test showed a positive result for steroids. Analysis using UV spectrophotometer showed the electronic transition n → л * and transition л → л *. Analysis using IR spectrophotometric showed functional groups OH, C = O, CO, aliphatic C-H, C = C, C-C, CH3 symmetric and C-H outside the field. Key word: Gardenia augusta, Merr, diabetes mellitus, steroids
Identifikasi Senyawa Alkaloid dari Akar Piper sarmentosum Roxb. Ex Hunter dan Uji Aktivitasnya terhadap Jamur Candida albicans Hartiwi Diastuti; Sadiah Achmad; Enny Ratnaningsih
Majalah Ilmiah Biologi BIOSFERA: A Scientific Journal Vol 22, No 2 (2005)
Publisher : Fakultas Biologi | Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mib.2005.22.2.96

Abstract

Piper sarmentosum Roxb. Ex Hunter or “Sirih duduk” has long been used for traditional medicine to cure various diseases, such as fungus infections. The investigation of the bioactive compounds of P. sarmentosum roots has not been carried out. This research was aimed to isolate the bioactive compounds from P. sarmentosum roots. The results showed that methanol extracts of P. sarmentosum roots have an activity on Candida albicans. The separation a bioactive compounds from methanol extracts of P. sarmentosum roots was performed by column chromatography, thin layer chromatography and recrystalizations. The identifications of the bioactive compounds were carried out using ultra violet spectrometry, infrared spectrometry, gas chromatography-mass spectrometry and nuclear magnetic resonance spectrometry. The results indicated that from methanol extracts, an alkaloid compound of piperoylpyrol derivative was 5-hydroxy-5- (3,4-methylenedioxyphenyl)-2-pentenoyl pyrol, could be purely isolated. Examination of bioactivity at concentration 0.10-2.50 mg/ml showed that this compound had an activity on C. albicans.
Pelatihan Pembuatan Tas Ecoprint Sebagai Produk Ecoprint Siap Pakai Ari Asnani; Hartiwi Diastuti; Eva Vaulina Yulistia Delsy; Waluyo Handoko
Serambi Abdimas Vol 3 No 2 (2022): Jurnal Serambi Abdimas
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.sa.2022.3.2.7338

Abstract

Ecoprint adalah teknik mencetak dan mewarnai berbagai material serat alam menggunakan pewarna alami. Aplikasi teknik ecoprint pada kain serat alam selanjutnya dapat dibuat beragam tas sebagai pengembangan produk ecoprint siap pakai. Berdasarkan hal tersebut maka telah dilakukan kegiatan pengabdian kepada masyarakat berupa pelatihan pembuatan tas fashion berbasis kain ecoprint dengan mitra Edukasi Bruwun Alas, Patikraja, Banyumas. Tahapan kegiatan mencakup pembuatan kain ecoprint, pembuatan pola tas, dan pembuatan tas menggunakan kain ecoprint. Hasil kegiatan menunjukkan dampak positif dimana mitra mampu menghasilkan ecoprint pada media kain, pola tas, dan produk tas ecoprint. Lima ragam tas yang dihasilkan adalah tas pouch, tas selempang, tas tote bag, tas ransel, dan tas kotak. Hasil kegiatan ini diharapkan mampu berkontribusi positif terhadap pengembangan keragaman produk ecoprint siap pakai.
Co-Authors Ari Asnani Chasani Mochamad Enny Ratnaningsih Eva Vaulina Yulistia Delsy Rizka Aprilia Sadiah Achmad Waluyo Handoko