E. Pudova
Engelhardt Institute of Molecular Biology, Russian Academy of Sciences

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HEXOKINASES IN BREAST CANCER S. Kharitonov; A. Zikiriahodzhaev; M. Ermoshchenkova; A. Sukhot’ko; M. Fedorova; E. Pudova; B. Alekseev; A. Kaprin; A. Kudryavtseva
International Journal of Biosciences and Biotechnology Vol 4 No 2 (2017)
Publisher : Central Laboratory for Genetic Resource and Molecular Biology, Faculty of Agriculture, Udayana University in cooperation with Asia-Oceania Bioscience and Biotechnology Consortium (AOBBC)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (163.827 KB) | DOI: 10.24843/IJBB.2017.v04.i02.p05

Abstract

Hexokinases are one of the key enzymes involved in the process of glycolysis. The level of expression of hexokinases is widely studied in breast cancer as a possible marker of unfavorable prognosis and aggressiveness of tumors. The level of expression of hexokinase may reflect the level of glycolysis activation and, thus, indicate samples with the most altered cellular metabolism.