Article Per Year (5 Year)
p-Index From 2021 - 2026
0
P-Index
This Author published in this journals
All Journal E-Jurnal Medika Udayana Indonesian Journal of Cardiology
Wayan Aryadana
Unknown Affiliation
Health Professions Medicine & Pharmacology

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
PREVALENSI FIBRILASI ATRIUM PADA PASIEN HIPERTIROIDISME DI POLIKLINIK ENDOKRIN RSUP SANGLAH Made Savitra Kusumadewi; Kadek Susila Surya Darma; Wayan Aryadana
E-Jurnal Medika Udayana Vol 9 No 7 (2020): Vol 9 No 07(2020): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2020.V09.i7.P10

Abstract

ABSTRAKFibrilasi atrium merupakan salah satu tipe aritmia yang paling umum ditemukan. Penyebab utama dari fibrilasi atrium adalah kelainan aktivitas kelistrikan jantung sehingga terjadi alirankembali impuls pada miosit jantung. Jika dilihat dari salah satu faktor risiko fibrilasi atrium,hal tersebut berhubungan dengan hipertiroidisme, karena fungsi vital hormon tiroid untukmelakukan regulasi ion Ca2+ pada miosit jantung yang berpengaruh pada fungsi sistolik dandiastolik jantung. Tujuan dari penelitian ini adalah untuk mengetahui prevalensi fibrilasiatrium pada pasien hipertiroidisme di poliklinik endokrin RSUP Sanglah Denpasar pada bulanJanuari 2018–Desember 2018, yakni jumlah pasien terdiagnosis fibrilasi atrium pada pasienrawat jalan yang sebelumnya sudah terdiagnosis hipertiroidisme atau pernah menjalanipengobatan untuk hipertiroidisme. Penelitian ini adalah penelitian deskriptif potong-lintangdengan desain studi kuantitatif, di mana Peneliti melakukan pengumpulan data denganmenggunakan data rekam medis. Terkumpul sebanyak 97 kasus yang memenuhi kriteriainklusi dan tidak memenuhi kriteria eksklusi. Diagnosis kerja hipertiroidisme berupa Grave’sdisease paling umum ditemukan pada 72 subyek (74,23%) dan didapatkan 6 kasus (6,19%)fibrilasi atrium pada subyek dengan diagnosis kerja hipertiroidisme. Dimana 5 (83,3%) dari 6kasus fibrilasi atrium didapatkan pada subyek dengan diagnosis kerja Grave’s disease, dan 3(50%) dari 6 kasus fibrilasi atrium didapatkan pada subyek dalam kelompok usia dewasaakhir (36-45 tahun). Hasil penelitian berupa, didapatkan 6 kasus fibrilasi atrium paroksismalpada 97 pasien rawat jalan dalam periode Januari-Desember 2018 dengan diagnosis kerjahipertiroidisme. Kata kunci: Fibrilasi atrium, Prevalensi, HipertiroidismeABSTRACT Atrial fibrillation known as one of the most common type of arrythmia. The main thing thatcaused atrial fibrillation was the disturbance in the electrophysiological activity of the heart,thus triggering impulse re-entry in the myocard. Given hyperthyroidism as one of the riskfactors for atrial fibrillation, thyroid hormone have a vital function of regulation Ca2+ ions onthe myocard that affects the heart’s diastolic and systolic function. The purpose of this studywas to find the prevalence of atrial fibrillation in hyperthyroidism patients at EndocrinePolyclinic, Sanglah General Hospital in between the months of January-December 2018, ofwhich the amount of atrial fibrillation diagnoses within outpatients whom previouslydiagnosed with hyperthyroidism or have been treated for hyperthyroidism. This study usedCross-Sectional Descriptive method with a quantitative study design, in which the data wasaccumulated through medical records. There were 97 elligible cases that fulfilled theinclusion criteria and were not excluded by the exclusion criteria. In this study, 72 subjects(74.23%) were diagnosed with Grave’s disease, thus it made Grave’s disease as the most common diagnosis of hyperthyroidism in this study, and 6 cases (6.19%) of atrial fibrillationwas noted in these subjects. Where 5 (83.3%) out of 6 of those atrial fibrillation cases wasfound within subjects with Grave’s disease as a working diagnosis, and 3 (50%) cases wasfound on subjects within late adults (36-45 years old) age group. The result of this study, wasthat 6 cases of paroxysmal atrial fibrillation was found within 97 outpatients withinJanuary-December 2018 period with Keywords: Atrial fibrillation, prevalence, hyperthyroidism
CORRELATION BETWEEN SERUM LEVEL GALECTIN-3 AND EARLY REMODELLING INDICATOR OF LEFT VENTRICLE IN PATIENT WITH ACUTE MYOCARDIAL INFARCTION DURING PRE-PERCUTANEOUS CORONARY INTERVENTION I Nyoman Indrawan Mataram; Wayan Aryadana; AA Wiradewi Lestari
Jurnal Kardiologi Indonesia Vol 40 No 1 (2019): Indonesian Journal of Cardiology: January-March 2019
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v40i1.799

Abstract

Background: Coronary heart disease (CHD) is a leading cause of death worldwide. Acute coronary syndrome (ACS) is a spectrum of CHD. Left ventricle remodelling is one of the complication with the bad outcome either short-term or long term. Early remodelling process (within 0-72 hours) post infarction can be assessed by circulating biomarker (Galectin-3), echocardiography, coronary angiography, and clinically. Objective: The aim of study is to know the correlation between serum level of Galectin-3 and early remodelling indicator in patient with acute myocardial infarction during pre-percutaneous coronary intervention. The parameters are LVEDV, LVEF, diastolic function component, TIMI flow, MBG, and presence of acute heart failure. Materials and Methods: This cross sectional study was conducted in Sanglah General Hospital during March-May 2018. A 62 sample was determined consecutively. Results: Bivariate analysis with Spearman correlation shows Galectin-3 correlated with LVEDV (r = 0,808; p= 0,000), E/e’ average (r = 0,297; p = 0,019), E/A ratio (r = 0,261; p= 0,041), and MBG (QuBE) (r = 0,647; p = 0,000). No correlation was found between Galectin-3 and LVEF Teich (r = -0,213; p= 0,097), LVEF Biplane (r = -0,226; p = 0,077), LAVI (r = 0,301; p = 0,170), e’septal (r = -0,079; p = 0,539), e’lateral (r = -0,092; p = 0,476), and TR Vmax (r=0,068; p=0,600). Chi square analysis shows no association between Galectin-3 and diastolic dysfunction left ventricle (OR= 1,032, p= 0,966, CI95%= 0,239-4,462), TIMI flow (OR= 1,032, p= 0,966, CI95%= 0,239-4,462), MBG score (OR= 0,264, p= 0,197, CI95%= 0,031-2,259), and acute heart failure (OR=0,577, p= 0,476, CI95%= 0,127-2,617). Multivariat analysis with multiple linear regression shows an increase in Galectin-3 has been proven associated independently with LVEDV, LAVI, E/e’ average, and E/A ratio. Multiple logistic regression shows Galectin-3 has not been proven independently with diastolic dysfunction, TIMI flow, MBG score, and acute heart failure. LVEDV is the best outcome that can be explained as its value influenced by constant, BMI, and Galectin-3 (R2 = 0,509). Conclusion: Galectin-3 correlated with LVEDV, average E/e’, E/A ratio, and MBG (QuBE). There is an independent association between Galectin-3 and LVEDV, LAVI, average E/e, and E/A ratio. Early remodelling process within 0-72 hours post infarction was happened pre-PCI. Anti-remodelling (including anti failure) during early phase is strongly recommended in order to prevent worse outcome in short and long term. Keywords: Galectin-3, early remodelling left ventricle, acute myocardial infarction, percutaneous coronary intervention.
Co-Authors Anak Agung Wiradewi Lestari I Nyoman Indrawan Mataram Kadek Susila Surya Darma Made Savitra Kusumadewi