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All Journal Acta Interna : The Journal of Internal Medicine Indonesian Journal of Biomedicine and Clinical Sciences
Iri Kuswadi
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience

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Correlation of Ferritin Level to The Quality of Life Ariyanto Nugroho; Iri Kuswadi; Bambang Djarwoto
Acta Interna The Journal of Internal Medicine Vol 4, No 2 (2014): The Journal of Internal Medicine
Publisher : Faculty of Medicine Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (143.139 KB) | DOI: 10.22146/acta interna.16926

Abstract

ABSTRACTBackground: Chronic kidney disease is a worldwide health problem. Circumstances that caused the condition of end-stage renal failure causes a decrease in quality of life with a high mortality rate ranging from 22% per year. Many ways to assess the quality of life, form-36 (SF-36) has undergone several revisions refi nement. Serum ferritin continues to be the focus of attention. Nearly half of all hemodialysis patients had serum ferritin > 500 ng/ml. Serum ferritin is a marker of infl ammation that is a good, low levels correlated with iron defi ciency and high levels correlated with infl ammation.Objective: To determine the correlation of high levels of serum ferritin to decline in the quality of life in patients with CRF who had been undergoing hemodialysisMethods: This study was a cross sectional study to determine whether high levels of serum ferritin may have an impact on the decline in the quality of life in patients with chronic renal failure (CRF) who had undergone regular hemodialysis. The study was conducted at Hospital Hemodialysis Unit Dr. Sardjito,Yogyakarta. Result: A total of 61 patients who met the inclusion criteria to undergo research. Score KDQOL-SF in this study, negative correlations (weak) significant in sleep (sleep disorders) 58.79 ± 1.95 (r = -0.306) and (p = 0.017). On the Role Physical scores (physical activity) 24.59 ± 3.21 obtained a negative correlation (weak) signifi cant (r = -0.268) and (p = 0.037). For Emotional Well Being scores (emotional condition) 70.85 ± 1.39 (r = -0.374) and (p = 0.003). On the score of Energy Fatigue (physical fatigue) 62.29 ± 1.61 (r = -0.261) and (p = 0.043).Conclusion: Overall, this study shows the lack of statistically signifi cant results showed a high correlation ferritin directly on quality of life.Keywords: chronic renal failure, hemodialysis, ferritin, KDQOL-SF
The Difference of Depression Score of Patients Failed Ultrafiltration Compared to Successful at Continuous Peritoneal Dialysis Patients in RSUP Dr. Sardjito Yogyakarta Padmi Bekti Lestari; Noor Asyiqah Sofia; Iri Kuswadi
Acta Interna The Journal of Internal Medicine Vol 10, No 2 (2020): Acta Interna The Journal of Internal Medicine
Publisher : Faculty of Medicine Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/actainterna.62840

Abstract

Background. High mortality and morbidity in patients with Chronic Kidney Disease (CKD) are associated with psychological problems and poor quality of life. Depression is a psychological problem most often found in groups of CKD patients undergoing renal replacement therapy. Specific research that links the failure of ultrafiltration in Continuous Ambulatory Peritoneal Dialysis (CAPD) patients with depression does not yet exist today. So that further research is needed regarding this matter so that various depression intervention approaches can be carried out in the group of patients undergoing CAPD.Aims. This study aimed to determine the difference in depressive score of patients who failed ultrafiltration compared to those who did not fail in patients undergoing Continuous Ambulatory Peritoneal Dialysis (CAPD) in RSUP dr. Sardjito Yogyakarta.Method. A cross-sectional analytic study to assess differences in depressive score of CAPD patients with ultrafiltration failure compared to those who did not fail ultrafiltration in CAPD Clinic of RSUP dr. Sardjito Yogyakarta. The research subjects consisted of 41 people who fulfilled the inclusion and exclusion criteria. Depression assessment was carried out by calculating the total score of the BDI-II questionnaire and analyzing it using the Mann-Whitney method.Result. The average value of BDI-II in this study was 12 ± 8. 1. Depression scores based on BDI-II are if the score is equal to or more than 17. In this study 7 research subjects (17.1%) are depression. BDI –II values in the non-ultrafiltration failure group 10.96±7.25 and in the failed group 13.38±9.73 with p= 0.633.Conclusion. There were no significant differences in BDI-II score between groups that failed and those  that did not fail ultrafiltration.
Improvement in left ventricle geometry and function after kidney transplantation Baiq Gerisa Rahmi Faharani; Hasanah Mumpuni; Yulia Wardhani; Metalia Puspitasari; Raden Heru Prasanto; Iri Kuswadi; Anggoro Budi Hartopo
Indonesian Journal of Biomedicine and Clinical Sciences Vol 56 No 01 (2024)
Publisher : Published by Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/inajbcs.v56i01.11774

Abstract

Chronic kidney disease (CKD) is associated with remodeling of the left ventricle (LV), affecting both its geometry and function. Kidney transplantation in patients with stage 5 CKD may lead to improvements in LV remodeling and result in better cardiac function. The aim of the study was to determine changes and improvements in LV geometry and function after kidney transplantation in patients with stage 5 CKD. This was an observational study conducted by collecting secondary data from the Hospital's Kidney Transplantation Registry, Dr. Sardjito General Hospital spanning the years 2017 to 2020. The study employed a comparative design, contrasting the results before and after treatment (kidney transplantation). We compared transthoracic echocardiographic parameters for LV geometry and function before and after kidney transplantation. The evaluation timeframe after kidney transplantation was divided into <12 and ³12 mo. A total of 27 patients qualified for inclusion in this study. In the <12 mon (n=20) evaluation group, there was a reduction in proportion of LV hypertrophy from 70% to 45%. There was an increase in global LV systolic function (ejection fraction) from 60.1±10.95% to 67.85±6.48% (p=0.014), and a decrease in LV diastolic dysfunction from 45% to 15% (p=0.07). In the ³12 mon (n=11) evaluation group, there was a decrease in the proportion of LV hypertrophy from 81.8 to 54.5%, an increase in global LV systolic function (ejection fraction) from 57.73±13.07% to 69.36±6.12% (p=0.011), and a decreased LV diastolic dysfunction from 63.6% to 0% (p=0.016). In conclusion, significant changes in LV geometry and function are observed following kidney transplantation, indicating improvements in these parameters. There are improvements in LV systolic function started at <12 mo and in LV diastolic function at ³12 mo after kidney transplantation.
Co-Authors Anggoro Budi Hartopo Ariyanto Nugroho Baiq Gerisa Rahmi Faharani Bambang Djarwoto Hasanah Mumpuni Metalia Puspitasari Noor Asyiqah Sofia Padmi Bekti Lestari Raden Heru Prasanto Yulia Wardhani