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All Journal Jurnal Kebijakan Kesehatan Indonesia Amerta Nutrition Review of Primary Care Practice and Education (Kajian Praktik dan Pendidikan Layanan Primer) Berita Kedokteran Masyarakat
Likke Prawidya Putri
Department Of Health Policy And Management, Faculty Of Medicine, Public Health, And Nursing, Universitas Gadjah Mada Yogyakarta
Education Health Professions Medicine & Pharmacology Nursing Public Health Other

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Journal : Amerta Nutrition

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Efektivitas Fortifikasi Pangan terhadap Kadar Hemoglobin pada Remaja: Tinjauan Sistematis dan Meta-Analisis: Effectiveness of Food Fortification to Anemia in Adolescents: A Systematic Review and Meta-Analysis Karomah, Ulfatul; Dewi, Ni Made Putri Kusuma; Putri, Likke Prawidya
Amerta Nutrition Vol. 8 No. 3SP (2024): AMERTA NUTRITION SUPPLEMENTARY EDITION Special 4th Amerta Nutrition Conferenc
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v8i3SP.2024.466-477

Abstract

Background: Anemia is still a global problem with nearly 2 billion people worldwide experiencing anemia by 2021. The population most vulnerable to anemia is adolescent girls. Anemia is prevalent in low- and middle-income countries. Food fortification is an anemia prevention strategy that is considered the most effective, economical, and able to reach the wider community. Objectives: To assess the effectiveness of iron (Fe)-fortified foods, whether or not supplemented with other micronutrients, on adolescent anemia in low- and middle-income countries. Methods: This research follows the PRISMA protocol and PICO rules. The databases used were PubMed, Scopus, Science Direct, and Cochrane. Study participants were adolescent girls aged 10-18 who received Fe-fortified food intervention. The comparison was adolescents who were given non-fortified food or a placebo. The outcome of interest was hemoglobin (Hb) level. Discussions: Of the 482 studies obtained, 10 studies were eligible, and eight studies proceeded to meta-analysis. The results of the meta-analysis showed that the mean change in Hb was higher in the intervention group compared to the control group. However, the variation between studies was heterogeneous (I2=97%, p-value<0.01). The highest mean difference value was fortification in soy sauce with 40 mg NaFeEDTA with Standardized Mean Difference (SMD)=2.88 mg/dL, while the lowest was rice fortification with SMD=0.01 mg/dL. Conclusions: This study can serve as a reference for creating intervention programs for fortification of foodstuffs to prevent anemia in adolescent girls in developing countries and upper-middle-income countries.
Co-Authors Agustina, Nika Maya Andreasta Meliala Anggoro Budi Hartopo Anggrahini, Dyah Wulan Bismantara, Haryo Deni Harbianto Deswanto Marbun Dewi, Ni Made Putri Kusuma Fajarwati, Prahesti Fitriah, Yunita Fitriana Murriya Ekawati Karomah, Ulfatul Laksono Trisnantoro Lucia Kris Dinarti Mawarni, Devina Bunga Muhammad Faozi Kurniawan Muhammad Reyhan Hadwiono Tiara Marthias Ulfayani Ramsar Wiradhika, Abdul Majid Halim Yodi Mahendradhata