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All Journal Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Academic Hospital Journal
Anton Sony Wibowo
Department Of Otorhinolaryngology – Head And Neck Surgery, Universitas Gadjah Mada Academic Hospital, Sleman, Yogyakarta Indonesia
Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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The role of thyroid stimulating hormone level as a predictive factor for advance stage thyroid carcinoma Bambang Udji Djoko Rianto; Anton Sony Wibowo; Camelia Herdini
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 51, No 4 (2019)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (267.249 KB) | DOI: 10.19106/JMedSci005104201908

Abstract

Thyroid stimulating hormone (TSH) is a cancer growth stimulus factor that have effect on the progression of thyroid carcinoma, common neck head malignancy. This hormonelevel has diagnostic value and can assist in the diagnosis, staging and management of the thyroid carcinoma.This study aimed to investigatethe role of TSH level as a predictor of advance stage thyroid carcinoma. This was case-control study involvingthyroid enlargement subjects who underwent thyroidectomy at Dr. Sardjito General Hospital, Yogyakartafrom 2015 to 2017. Cancer staging examination using AJCC 2102and TSH levels examination were conducted before underwent thyroidectomy.The inclusion criteria for case group were advanced stage(stage III and IV), while for control group wereearly-stage of thyroid carcinoma (stage I and II). The exclusion criteria for both case and control groups were 1) suffering from thyroid hormone disorders requiring therapy before thyroidectomy, 2) receiving thyroid suppression therapy prior to thyroidectomy. Sixty-six post thyroidectomy patients were involved in this study. The patients were divided into case and control groups consisted of 33 patients in each group. Based on receiver operating characteristic curve, the cut of point 1.27 mIU/L for TSH was obtained with sensitivity of 72.7% and specificity of 78.8%. There was statistically significant difference TSH levelsbetween early stage thyroid carcinoma and late stage thyroid carcinoma(p = 0.001;OR: 9.9;95% CI: 3.19-30.15).It can be concluded that TSHlevels ≥ 1.27mIU/L as predictor of advance stage thyroid carcinoma.
Association between hearing loss and hypertension in non ear infection patients in Universitas Gadjah Mada Academic Hospital Anton Sony Wibowo; Herfis Avidati; Sulis Ernawati
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 52, No 3 (2020)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (199.961 KB) | DOI: 10.19106/JMedSci005203202007

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Hearing loss is a common occurrence that can decrease productivity and quality of life. The incidence of hearing loss is often experienced by adults due to several factors, and one influencing factor is cardiovascular disease. Hypertension is known to have an effect on decreasing inner ear vascularization that will result in hearing loss. The objective of this study was to evaluate the association of hearing loss and hypertension in non-ear infection patients. This case-control study recruited subjects who underwent audiometric examination at the Universitas Gadjah Mada Academic Hospital, Yogyakarta, from June 2018 - July 2019. Hypertension was determined based on the results of blood pressure examination based on JNC 8 criteria. Hearing threshold value was taken from pure tone audiometry. The association of hypertension with hearing loss was analysed in each group and between study groups. Sixty patients who underwent audiometric examination divided into two groups with 30 patients in each group were involved in this study. There was a significant relationship between hypertension and hearing loss (OR=13.1; 95%CI: 3.8-45.0; p= 0.001). Hypertension acts as a variable that significantly affects the incidence of hearing loss. Patients with hypertension have a greater risk of hearing loss compared to patients without hypertension.
Clinical Profile of Impaired Hearing in Children with Autism Spectrum Disorder (ASD) at UGM Academic Hospital Lestari, Ade Febrina; Sitaresmi, Mei Neni; Wibowo, Anton Sony; Sari, Shinta Kusumalarna; Ridhayanti, Firda
Academic Hospital Journal Vol 6, No 2 (2024)
Publisher : Rumah Sakit Akademik Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ahj.v6i2.98785

Abstract

Background: Hearing tolerance is impaired in children with Autism Spectrum Disorder (ASD), which can affect social and academic functioning. This study aims to describe the clinical profile of hearing impairments in children with ASD and determine the prevalence of such impairments. Method: A cross-sectional study was conducted at Academic Hospital UGM on pediatric ASD patients aged 18 months to 12 years who underwent hearing exams like BERA (brain-evoked response auditory) and/or audiometry. ASD severity was assessed using the Childhood Autism Rating Scale (CARS) and a questionnaire on demographics and comorbidities, followed by BERA tests. Results:  A total of 41 ASD children were obtained, with 31 children (76%) being boys and an average diagnosis age of 3.3 years (±1.3 SD). Hearing loss was suffered by 4 children (10%) and 37 children (90%) did not experience hearing loss. Sound sensitivity and degree of ASD correlated with head banging (p=0.01), and male gender correlated with hearing loss (P=0.006). CARS score was statistically associated with sound sensitivity (p=0.041) and degree of ASD (<0.001). Conclusion: Children diagnosed with ASD face an increased susceptibility to communication impairments which can be attributed to hearing impairments. This issue warrants particular attention in the context of ASD, highlighting the necessity for thorough screening of hearing capabilities.
Co-Authors Bambang Udji Djoko Rianto Camelia Herdini Herfis Avidati Lestari, Ade Febrina Mei Neni Sitaresmi Ridhayanti, Firda Sari, Shinta Kusumalarna Sulis Ernawati