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All Journal Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Cardiovascular and Cardiometabolic Journal (CCJ)
Steven Philip Surya
Army Hospital Kesdam Jaya Cijantung, Jakarta
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience

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Angiotensin converting enzyme 2 (ACE2), COVID-19 and cardiac injury: what cardiologist should know Sidhi Laksono; Budhi Setianto; Steven Philip Surya
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 52, No 3 (2020): Special Issue: COVID-19
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (197.966 KB) | DOI: 10.19106/JMedSciSI005203202009

Abstract

Coronavirus disease 2019 (COVID-19) has already stated as a pandemic by the World Health Organization (WHO). Until now, Indonesia has also infected with this severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. All medical staffs join hand by hand to overcome this pandemic, not only pulmonologist but also cardiologist. Early reports from China showed that cardiovascular comorbidities add more mortality than without comorbid. Cardiac implication of this infection is cardiac injury. Viral pathology and pathophysiology that induced cardiac injury is still debatable and not well understood. Angiotensin-converting enzyme 2 (ACE2) has emerged as a key regulator of renin-angiotensin system in cardiovascular disease. ACE2 has been postulated as one of the pathophysiology of COVID-19 and cardiac injury.
Lymphatic Disease in Cardiology: The Forgettable One Sidhi Laksono Purwowiyoto; Novi Anggriyani; Steven Philip Surya
Cardiovascular and Cardiometabolic Journal Vol. 1 No. 2 (2020): Cardiovascular and Cardiometabolic Journal
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ccj.v1i2.2020.77-81

Abstract

Before molecular medicine era, the lymphatic system was not getting enough attention in medicine world, especially in cardiovascular medicine. Our knowledge about lymphatic system is far left behind compare to vascular system. Many believes lymphatic function is isolated in regulate interstitial fluid hemostasis, fat transport, and immune transport. In deep investigation in lymphatic function shows that alteration in lymphatic vessel could disrupt normal cardiovascular function. Moreover, optimal cardiac lymphatic condition after post-heart tissue injury could enhance tissue regeneration. That is why in modern medicine era preserving optimal lymphatic condition and treat abnormal lymphatic condition might be beneficial in cardiovascular medicine.
Co-Authors Budhi Setianto Novi Anggriyani Sidhi Laksono Sidhi Laksono Purwowiyoto Sidhi Laksono Purwowiyoto