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Prihwanto Budi Subagijo
RSD dr. Soebandi Jember
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Hubungan antara Profilaksis Kotrimoksazol dan Prevalensi Toksoplasmosis pada Pasien HIV Positif di Jember (The Association Between Prophylactic Cotrimoxazole and the Prevalence Toxoplasmosis in HIV-Positive Patients in Jember) Elly Febry Taufany; Afifah Machlaurin; Prihwanto Budi Subagijo
Pustaka Kesehatan Vol 6 No 1 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i1.6613

Abstract

Human immunodeficiency virus (HIV) is a virus that causes acquired immune deficiency syndrome (AIDS). HIV is a high mortality disease and the number of patients is increasing recent days. Based on dr. Soebandi Jember Hospital report in 2015, there were 1,492 HIV patients and 455 people received antiretroviral (ARV) therapy. Toxoplasmosis is one of opportunistic infections commonly found in HIV patients in central nervous system. WHO has issued guidelines for the use of cotrimoxazole as prophylaxis in HIV positive people. The purpose of this study was to determine the relationship between cotrimoxazole prophylaxis and the incidence of toxoplasmosis. This research was a case control study with retrospective approach and used chi-square analysis. The results showed that most patients were male (57%), 20-29 years in age (50%), and 41-60 kg in weight (64%). Based on the CD4 level, most HIV patients were less than 350/mm3 (96%) and total lymphocite count (TLC) also less than 1,200/mm3 (42%). There were 1 patient from 76 patients with cotrimoxazole prophylaxis and 7 patients from 52 patient without cotrimoxazole prophylaxis who developed toxoplasmosis. Based on chi-square analysis, cotrimoxazole prophylaxis reduce the incidence of toxoplasmosis in HIV positive (p-value 0,004). Keywords: HIV/AIDS, prophilaxis therapy of cotrimoxazole, toxoplasmosis infection
Identifikasi Drug Related Problems (DRPs) pada Terapi Diabetes Melitus Tipe 2 di Instalasi Rawat Inap RSD dr. Soebandi Jember Periode Tahun 2015 (Identification of Drug Related Problems (DRPs) for Type 2 Diabetes Mellitus Therapy in Hospitalized Patients Khoirotun Nazilah; Ema Rachmawati; Prihwanto Budi Subagijo
Pustaka Kesehatan Vol 5 No 3 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v5i3.5891

Abstract

Diabetes mellitus (DM) is a degenerative disease which causes various complications that require patients to use polypharmacy. The use of polypharmacy has been reported to be one of the causes of drug related problems (DRPs). DRPs are unexpected events related to the treatment undergone by the patient. This study aimed to avoid DRPs so that patients could receive the best treatment. This research used total sampling method and conducted retrospectively using medical records of patients with type 2 diabetes which were hospitalized in RSD dr. Soebandi Jember in 2015. As many as 15 patients (25%) of 60 patients experiencing DRPs were included in the six criteria of DRPs. This criteria included unnecessary drug therapy found in 1 patient (6,67%), need for additional drug therapy found in 1 patient (6.67%), ineffective drug found in 4 patients (26,67%) and drug interactions found in 10 patients (66.67%). Eventhough too high dosage and too low dosage was not found in all patient samples. Keywords: type 2 diabetes mellitus, drug related problems (DRPs), antidiabetic, hospitalized
Analisis Efektivitas Biaya Penggunaan Antibiotik terhadap Pasien Sepsis di RSD dr. Soebandi TahunAnalisis Efektivitas Biaya Penggunaan 2014-2015 (Cost Effectiveness Analysis of Antibiotic Used for Sepsis Patients in dr. Soebandi Hospital During 2014-2015) Putri Kartika Ningsih; Prihwanto Budi Subagijo
Pustaka Kesehatan Vol 5 No 1 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v5i1.5385

Abstract

Sepsis is a medical condition that is difficult to be identified and diagnosed. Sepsis often occurs to hospitalized patients in the hospital. Treatment with antibiotics is one of the factors supporting the success of sepsis treatment. The purpose of this study was to determine the most effective empirical antibiotics based on the cost effectiveness of adult and geriatric sepsis patients in RSD dr. Soebandi Jember during 2014-2015. This observational study was conducted by retrospective data collection. Data was collected from hospitalized sepsis patients medical records and received empirical antibiotics therapy at least three days. The parameters used in this study were costs which included the cost of accommodation, examination support, services, medicines, and medical devices, while the effectiveness used the length of stay, length of antibiotic related and the patients life expectancy. The results of incremental cost effectiveness ratio (ICER) showed that meropenem antibiotic had a lower cost Rp 378,808.07 compared to ceftazidime and cefotaxime. It can be concluded that meropenem antibiotic was more cost effective than ceftazidime and cefotaxime antibiotics. Keywords: cost effectiveness, pharmacoeconomic, antibiotic, sepsis
Co-Authors Elly Febry Taufany Ema Rachmawati Khoirotun Nazilah Machlaurin, Afifah Putri Kartika Ningsih