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All Journal Jurnal Kedokteran Diponegoro e-Journal Pustaka Kesehatan JAIM (Jurnal Abdi Masyarakat) Jurnal Puruhita Natural Science Education Research (NSER) e_Jurnal Ilmiah Riset Akuntansi
Laily Rahmawati
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Humanities Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Health Professions Library & Information Science Medicine & Pharmacology Physics Public Health Social Sciences Other

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Peningkatan Nilai Tambah Daun Kopi (Coffea Sp) Menjadi Ecoprint di Desa Mento, Kec. Candiroto, Kab. Temanggung Suraya, Fatona; Sholikhah, Nur Mahiyatus; Rahmawati, Laily; Rusmawati, Syntya Defi; Sagitania, Dhita
Jurnal Puruhita Vol 3 No 2 (2021): August 2021
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/puruhita.v3i2.53101

Abstract

Pemanfaatan tanaman kopi di desa Mento hanya terfokus pada pengolahan biji kopi sebagai minuman seduh. Daun kopi merupakan salah satu bagian dari tanaman kopi yang belum dimanfaatkan sehingga masih banyak yang terbuang sia-sia dan menjadi limbah organik saja. Upaya memanfaatkan daun kopi untuk dijadikan sebuah produk yang memliki nilai ekonomis adalah melalui pelatihan pembuatan ecoprint dengan pemanfaatan bahan alami dari daun kopi (coffea sp).Teknik ini memanfaatkan tumbuhan sebagai bahan utama dalam pembuatan motif dengan cara memindahkan bentuk dan warna tumbuhan pada kain. Melalui kerja sama dengan ibu-ibu PKK Desa Mento, program pelatihan pembuatan ecoprint yang dilaksanakan oleh KKN ini bertujuan untuk meningkatkan kualitas sumber daya ibu-ibu PKK di desa Mento. Tujuan lain dari kegiatan ini adalah untuk memberikan pengetahuan dan keterampilan dalam memanfaatkan daun kopi menjadi produk yang bernilai jual tinggi. Metode pelaksanaan program adalah dengan pelatihan serta praktek langsung dalam pembuatan ecoprint. Luaran yang dicapai adalah sebuah produk yaitu batik ecoprint dengan motif dari daun kopi dan brosur pembuatan ecoprint serta menambah pengetahuan dan keterampilan ibu-ibu PKK.
Efektivitas Ekstrak Artemisia vulgaris L. sebagai Hepatoprotektor pada sel-sel Hati Tikus yang Diinduksi Niasin Laily Rahmawati; Erma Sulistyaningsih; Rosita Dewi
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.7617

Abstract

The niacin in energy drinks has metabolic product that cause oxidative stress and liver damage, while the liver damage can be prevented by hepatoprotective agents. Scoparone in Artemisia vulgaris L. can act as a hepatoprotector by its antioxidant effect. This study aimed to investigate the effectivity of Artemisia vulgaris L. extract as a hepatoprotector in wistar hepatocytes induced by niacin. This study used 25 male rats which were divided into 5 groups: normal, the negative control, the positive control, the treatment group I, and II. Treatment was conducted for 28 days. The samples were terminated and the hepatocyte were prepared for histological examination. Histological appearance was catagorized as mild, moderate, and severe damage with or without inflamatory cells activity. The data analysis by Kruskal Wallis showed significant difference (p<0,001). Further analysis by Mann Whitney revealed significantly difference (p<0,05) between normal group and all groups, negative control group and positive control group, and positive control group and treatment group I, but not significantly difference between negative control group and treatment group I, negative control group and treatment group II, positive control group and treatment group II, and between treatment groups. The study concluded that the effectivity of Artemisia vulgaris L. extract has not been proven as a hepatoprotector but further study is needed to draw a definite conclusion. Keywords: energy drink, niacin, Artemisia vulgaris L., hepatoprotector
FAKTOR-FAKTOR YANG MEMPENGARUHI TINDAK PIDANA KORUPSI APARAT PEMERINTAH DAERAH Laily Rahmawati; Maslichah Maslichah; M. Cholid Mawardi
e_Jurnal Ilmiah Riset Akuntansi Vol 8, No 06 (2019): e_Jurnal Ilmiah Riset Akuntansi Agustus 2019
Publisher : Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (612.041 KB)

Abstract

ABSTRACTThis study aims to determine the factors that influence the corruption of local government officials. The population in this study were Malang city government employees. Samples used. The technique used in sampling is purposive sampling technique, the sample chosen was 139 respondents. Data was taken using the questionnaire method. The data analysis method used is multiple regression analysis with the help of SPSS version 16 software (Product Statistics and Solution Services version 16). The test data used is the simultaneous hypothesis test (f), determination coefficient (R2), and partial hypothesis test (t). The results of the study indicate that simultaneously the independent variables significantly influence the dependent variable. Based on the test results of the coefficient of determination, the adjusted R value is 87.9% while the remaining 12.1% is influenced by other variables not included in this study. Based on the results of partial tests of individual behavior variables have a positive effect on criminal acts of corruption, government organizations have a negative influence on corruption, per law has a positive effect on criminal acts of corruption, supervision has a positive effect on corruption.Keywords: individual behavior, government organization, by law, supervision
ANALISIS PROFIL KETERAMPILAN PROSES SAINS DALAM PEMBELAJARAN KIMIA Rahmawati, Laily
Natural Science Education Research Vol 8, No 2 (2025): Natural Science Education Research
Publisher : Program Studi Pendidikan IPA, Universitas Trunojoyo Madura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21107/nser.v8i2.30493

Abstract

Keterampilan Proses Sains identik dengan keterampilan yang mendukung pada penguasaan konsep dan pemikiran reflektif dalam pemecahan masalah sehingga memungkinkan individu untuk berkembang secara kreatif dan berdaya saing. Penelitian ini bertujuan untuk memetakan tingkat KPS pe kelas XI SMA Negeri 16 Semarang. Penilaian dilakukan hanya mencakup enam indikator KPS. Sejumlah 40 siswa menjadi subjek penelitian. Penelitian ini menerapkan metode penelitian deskriptif kuantitatif. Data diperoleh melalui tes keterampilan proses sains. Hasil tes menunjukkan bahwa nilai rata-rata KPS yang dimiliki siswa masih terklasifikasi sebagai kurang memadai, karena nilai nilai rata-rata sebesar 27,6. Berdasarkan analisis data dideskripsikan kemampuan analisis siswa pada indikator mengamati 30, klasifikasi 13.75, menginterpretasi 23.75, mengajukan pertanyaan 36.88,  menerapkan konsep 25, serta menggunakan alat dan bahan 36.25 dengan keseluruhan termasuk kriteria kurang memadai.
PENDAMPINGAN KELAS MINI ZOO EDUKATIF UNTUK PENGEMBANGAN GEOPARK PENANGKARAN RUSA MALO KABUPATEN BOJONEGORO Susilo, Joko; Rahmawati, Laily; Romadhoni, Novita; Wahyuni, Novi; Susanti, Diana
Jurnal Abdi Masyarakat Vol. 9 No. 1 (2025): Jurnal Abdi Masyarakat November 2025
Publisher : Universitas Kadiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30737/jaim.v9i1.6709

Abstract

Early childhood education plays an important role in fostering children's growth and character development. However, its implementation often focuses on cognitive aspects and pays little attention to character growth. This community service activity focused on strengthening the function of the Timor Deer Breeding Center in Malo Village, Bojonegoro, through an outdoor learning approach based on an educational mini zoo. The program aimed to improve the quality of early childhood education while optimizing the role of the breeding center as a means of conservation and educational tourism. The implementation methods included needs identification, facility revitalization, mini zoo class assistance, and evaluation. The results of the assistance showed high enthusiasm from the participants and an increase in community visits by 44.26%. These findings confirm that educational mini zoos contribute to character building in children, environmental preservation, and local community empowerment.
METTL25 EXPRESSION PROFILING ACROSS HUMAN TISSUES AND CANCERS Aziz, Nur; Rahmawati, Laily; Qomaladewi, Nurinanda Prisky
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 15, No 3 (2026): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v15i3.53300

Abstract

Background: Although recent studies have established the critical roles of methyltransferases in epigenetic regulation and cellular homeostasis, the biological function of METTL25, a member of this enzyme family, is not well known. Current clinical research has identified various methyltransferases as key regulators of gene expression, yet METTL25 remains functionally uncharacterized, representing a significant knowledge gap in our understanding of methyltransferase biology. Objective: This study examines the expression patterns of METTL25 across normal human tissues and cancer contexts to identify its potential physiological and pathological roles and to understand its regulatory mechanisms in health and disease. Methods: We conducted a systematic computational analysis using large-scale publicly available transcriptomic and proteomic datasets. Expression patterns were analyzed across normal human tissues and cancer cell lines. Correlation analysis between mRNA and protein levels was performed, followed by differential gene expression analysis comparing thyroid carcinoma to normal thyroid tissue. Functional enrichment analysis was applied to identify biological pathways associated with METTL25 expression. Results: METTL25 exhibited tissue-specific expression patterns with highest expression observed in endocrine organs (thyroid, adrenal glands) and immune compartments (lymphoid tissues). Moderate correlation between mRNA and protein levels was identified (r=0.404 ; p=0.001), indicating transcriptional control of protein abundance. METTL25 expression was significantly downregulated in thyroid carcinoma compared to normal thyroid tissue (p<0.01). Higher METTL25 expression in tumors was statistically significant and positively correlated with gene signatures related to wound healing, coagulation, and hemostasis pathways. Conclusion: METTL25 functions as a tissue-restricted methyltransferase with tumor suppressor characteristics in thyroid cancer. The positive correlation between METTL25 expression and wound healing pathways was statistically significant, suggesting its involvement in tissue repair mechanisms. These findings provide the foundation for future mechanistic studies investigating METTL25's role in cancer biology and its potential as a therapeutic target.
Co-Authors Aziz, Nur Diana Susanti Erma Sulistyaningsih Fatona Suraya, Fatona Joko Susilo M. Cholid Mawardi Maslichah, Maslichah Novi Wahyuni Qomaladewi, Nurinanda Prisky Romadhoni, Novita Rosita Dewi Rusmawati, Syntya Defi Sagitania, Dhita Sholikhah, Nur Mahiyatus