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Nia Kristiningrum
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Optimasi Zink Oksida Dan Asam Malat dalam Krim Tabir Surya Kombinasi Avobenzone dan Octyl Methoxycinnamate dengan Desain Faktorial Viddy Agustian Rosyidi; Lisanul Ummah; Nia Kristiningrum
Pustaka Kesehatan Vol 6 No 3 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i3.9871

Abstract

Ultraviolet rays (UV) has an adverse effect on the skin, which is epidermis damage. One way to prevent the adverse effects of UV rays on the skin can be done by using sunscreen. The sunscreen mechanism of action was divided into chemical absorber and physical blocker. Chemical absorber will be degradated when exposed to UV rays, while ZnO as physical blocker can increase pH value of the sunscreen. The effectiveness of sunscreen was affected by pH value, so malic acid was added into the sunscreen formula to decrease pH value. This study was aimed to determine the optimum composition of ZnO and malic acid on pH, viscosity, SPF, transmission of erythema and transmission of pigmentation using factorial design method. 0,5% ZnO was set as the lowest level and 3% ZnO was set as the highest level; 0,5% malic acid was set as the lowest level and 0,8% malic acid was set as the highest level. Selected optimum formula was 0,5% ZnO and 0,8% malic acid with the predicted SPF value of 21,242; TE of 0,000; TP of 0,000; pH of 4,820; and viscosity of 80,333 dPa.s Keywords: sunscreen, Zinc Oxide, malic acid, Sun Protector Factor
DETERMINATION OF TOTAL PHENOLIC CONTENT AND ANTIOXIDANT ACTIVITY IN METHANOLIC EXTRACT OF ROBUSTA AND ARABICA COFFEE LEAVES Nia Kristiningrum; Yeni Nur Cahyanti; Lestyo Wulandari
UNEJ e-Proceeding Proceeding of 1st International Conference on Medicine and Health Sciences (ICMHS)
Publisher : UPT Penerbitan Universitas Jember

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Abstract

Phenols contained in coffee beans may also found inthe coffee leaves. Previous research showed that thearabica coffee leaves contain phenolic compounds[1]. Phenolic compounds are compounds that haveone or more hydroxyl groups attached directly to anaromatic ring [2]. Phenolics compounds have manybiological effects, including antioxidant activity [3].Antioxidants are the first line for defense againstfree radical damage, and important for health. Theneed for antioxidants becomes even more criticalwith increased exposure to free radicals. Pollution,cigarette smoke, drugs, illness, stress, and evenexercise can increase free radical exposure [4].The aim of this study was to determine totalphenolic content and antioxidant activity inmethanolic extracts of robusta and arabica coffeeleaves (old and young leaves), as potential sources ofnatural antioxidants. The relationship betweenphenolic content and antioxidant activity was alsoinvestigated.
Co-Authors Lestyo Wulandari Lisanul Ummah Viddy Agustian Rosyidi Yeni Nur Cahyanti