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Prihwanto Budi Subagio
RSD dr. Soebandi Jember
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Efektivitas Penggunaan Insulin pada Penderita Diabetes Melitus dengan Kehamilan di Rawat Inap RSD dr. Soebandi Jember Tahun 2012-2013 (Effectivity of Insulin Usage on Diabetic Mellitus Gestational Hospitalized Patient at RSD dr. Soebandi Jember in 2012-20 Riza Rastri Wihardiyanti; Prihwanto Budi Subagio; Fifteen Aprila Fajrin
Pustaka Kesehatan Vol 3 No 3 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Gestational diabetes melitus is a diseases that are frequently happen to pregnant women, and is happen to be one of the causes of mortality on mother and fetus. The use of drugs during pregnancy should be prudentially considered for pregnant women, since they are not allowed to consume anti-diabetic drug (OAD) and just allowed to use insulin as therapy. The purpose of this study was to describe the use of insulin, as well as assessing the effectiveness of insulin therapy in patients with gestational diabetes mellitus in RSD dr. Soebandi Jember. The sample in this study was taken from 23 patients. We found that the disease affect 7.69% patients of 20-24 years of age, 11.54% patients of 25-29 years of age, 26.92% patients of 30-34 years of age, 30.77% patients of 35-39 years of age, 7.69% patients of 40-44 years of age and 15.38% patients of above 45 years of age. The insulin used in the sampling is Actrapid for 10 patients and Novorapid for 4 patients. It is known that the effectiveness of insulin based on blood glucose random levels with insulin Actrapid and Novorapid in sub-cutaneous do not have significant differences. Keywords: diabetic mellitus gestational, insulin, antidiabetic drugs
Pengaruh Faktor Klinik dan Pengobatan terhadap Keberhasilan Terapi Tuberkulosis pada Pasien HIV–TB di Jember (The Influences of Selected Clinical Factors and Treatment on Tuberculosis Therapy Outcome among HIV-TB Patients in Jember) Nuraini Agustin; Afifah Machlaurin; Prihwanto Budi Subagio
Pustaka Kesehatan Vol 5 No 2 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v5i2.5861

Abstract

Human imunodeficiency virus (HIV) is an infectious diseases that become an international problem. Since 1980s, there was an increase in morbidity and mortality due to tuberculosis (TB) infection in high HIV prevalence areas. The success of therapy is very important in the treatment of HIV-TB patients. The purpose of this study was to determine the factors that influence the success therapy in HIV-TB patients. This research was a cross sectional study with retrospective approach and used chi square analysis. The result showed that most patients were male (62.1%) and most were 25-34 years in age (42.3%). Most HIV-TB patients were 41-50 kg in weight (56.9%). They had CD4 level range of 50-199/mm3 and total lymphocyte count (TLC) less than 1,200/mm3 (58.6%). Most HIV-TB received therapy TB category 1 that was 55.2%, and antiretroviral (ARV) combination of TDF+3TC+EFV (91.8%). Based on chi square analysis, body weight, CD4 level, and TLC affected the success therapy (P value 0.022, 0.003, 0.028), whereas age and gender didn't (P value 0.222, 0.905). On the other hand, the variation therapy of TB and HIV didn't affect the success therapy either (P value 0.943, 0.718).Keywords: HIV-TB, antiretroviral, tuberculosis therapy
Analisis Efektivitas Biaya Penggunaan Antibiotik terhadap Pasien Sepsis Pediatrik di Rawat Inap RSD dr. Soebandi Kabupaten Jember pada Tahun 2014 (Cost effectiveness Analysis of Antibiotics in Hospitelized Pediatric Sepsis Patients at RSD dr. Soebandi Je Nurul Faridah; Afifah Machlaurin; Prihwanto Budi Subagio
Pustaka Kesehatan Vol 4 No 2 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Antibiotics play an importent role in sepsis therapy. Inappropiate antibiotic theraphy leads to resistance of antibiotic resulting increase length of stay (LOS), mortality, and higher cost. The purpose of this study was to determine the most effective empirical antibiotic based on cost effectiveness analysis (CEA) in pediatric patients with sepsis at RSD dr. Soebandi in 2014. This study observed medical and payment records retrospectively. From 152 patient analyzed, 51 patients included and 136 patients were excluded because of the antibiotic theraphy less than three days, the age more than 18 years old and the data was not complete. The effectiveness parameter of this study were length of stay (LOS), length of stay antibiotic related (LOSAR) and 28-days mortality. According to this study, ampicillin sulbactam plus amikacin combination had shorter LOS (13,82 days) than other antibiotics. However monotheraphy ampicillin sulbactam had shorter LOSAR (7.13 days) and lower 28-days mortality (50.00%). The total cost and antibiotic cost analysis showed that ampicillin sulbactam plus amikacin combination was cheaper than other antibiotics (Rp 5,130,000.00 ± 500.00). Based on CEA and quadrant analysis ampicilin sulbactam combination plus amikacin was the most cost effective with low cost and high effectiveness (quadrant II) than other antibiotic.   Keywords: cost effectiveness, antibiotic, sepsis
Co-Authors Fifteen Aprila Fajrin Machlaurin, Afifah Nuraini Agustin Nurul Faridah Riza Rastri Wihardiyanti