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PENGARUH FORMALIN PERORAL TERHADAP KADAR SGOT dan SGPT TIKUS WISTAR Ayu Rindwitia Indah Peanasari; Sri Latiyani Djamil; Afiana Rohmani
Jurnal Kedokteran Muhammadiyah Vol 2, No 1 (2013): JURNAL KEDOKTERAN
Publisher : Jurnal Kedokteran Muhammadiyah

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Abstract

Latar Belakang: Formalin merupakan zat yang bersifat iritatif. Senyawa formalin masuk ke dalam tubuh akan didetoksifikasi dan dimetabolisme oleh hepar dan menghasilkan zat xenobiontin yang dapat merusak fungsi hepar. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian formalin peroral terhadap kadar SGOT dan SGPT pada tikus Wistar (Rattus norvegicus)Metode: Penelitian ek s p er i m en t al l a bor at or i k in i m en g g un a kan post test only control group design. Jumlah sampel sebanyak 18 ekor tikus Wistar yang telah memenuhi kriteria ekslusi dan inklusi. Tikus diadaptasi selama 7 hari, pada hari ke-8 tikus dibagi secara simple random sampling menjadi 2 kelompok. Kelompok kontrol diberi Placebo peroral. Kelompok Perlakuan diberi formalin peroral 0.1mL/kgBB/hari, Setelah 2 minggu semua sampel penelitian dilakukan pemeriksaan kadar SGOT dan SGPT. Analisis menggunakan uji Independent Sampel T Test.Hasil:. Hasil uji statistik kadar SGOT dan SGPT pada kelompok kontrol dan perlakuan diperoleh p=0,000. Berdasarkan uji tersebut terdapat signifikasi pengaruh pemberian kelompok formalin dibandingkan kelompok kontrol (placebo) terhadap kadar SGOT dan SGPT tikus Wistar.Kesimpulan: Kadar SGOT dan SGPT hepar pada kelompok tikus Wistar yang diberi formalin peroral lebih tinggi dibandingkan kelompok kontrol.Kata kunci: formalin peroral, kadar SGOT dan SGPT
TINJAUAN PUSTAKA: TANTANGAN DAN IMPLEMENTASI PEMBAYARAN JASA KESEHATAN DALAM SISTEM JAMINAN KESEHATAN NASIONAL (JKN) Ayu Rindwitia indah Peanasari; Vip Paramarta
Multidiciplinary Output Research For Actual and International Issue (MORFAI) Vol. 5 No. 3 (2025): Multidiciplinary Output Research For Actual and International Issue
Publisher : RADJA PUBLIKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54443/morfai.v5i3.4136

Abstract

This study aims to examine the challenges and implementation of medical service payments within the National Health Insurance (JKN) system in Indonesia through a literature review. The implementation of JKN demonstrates significant efforts to strengthen healthcare governance, including through the implementation of INA-CBGs-based payment mechanisms, the use of the Mobile JKN application, and strengthening the membership system. However, the literature review reveals that various challenges remain, such as barriers to socialization in certain regions, limitations in the usability of digital applications, the potential for fraud in the claims system, inefficiencies in drug planning and procurement, and issues with the sustainability of membership and the implementation of the tiered referral system. These findings confirm that the effectiveness of medical service payments within JKN is determined not only by the claims mechanism but also by social, technological, regulatory, and healthcare governance factors. Therefore, strong synergy is needed between the government, BPJS Kesehatan (Social Security Agency for Health), healthcare facilities, medical personnel, and the community to ensure the achievement of JKN's primary objectives, namely equitable access and sustainable improvement of healthcare quality.