Article Per Year (5 Year)
p-Index From 2021 - 2026
0
P-Index
This Author published in this journals
All Journal Pharmaciana: Jurnal Kefarmasian
Kusmiyati kusmiyati
Fakultas Farmasi UAD
Medicine & Pharmacology

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
ISOLASI DAN IDENTIFIKASI ZAT AKTIF EKSTRAK METANOL RIMPANG KUNYIT PUTIH (Curcuma mangga Val) FRAKSI ETIL ASETAT Kusmiyati kusmiyati; Nurfina Aznam; Sri Handayani
Pharmaciana Vol 1, No 2 (2011): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (129.3 KB) | DOI: 10.12928/pharmaciana.v1i2.519

Abstract

Curcuma mangga contains a lot of variety of active compound which use as traditional medicines. This research aimed to isolated and determinated the active compound of methanol extract Curcuma mangga rhizomes of ethyl acetate fraction and its rendemen. Amount of 1000 g Curcuma mangga rhizomes was macerated with methanol solvent at room temperature for 24 hours. Remaceration was done seventh times. Methanol extract was fractionated with ethyl acetate. About 39,05 g of concentrated ethyl acetate fraction was then separated by Column Chromatography. According to the similarity of UV-Vis spectra and GC-MS, active compound in methanol extract Curcuma mangga rhizomes ethyl acetate fraction is predicted as Labda-8(17),12-dien-15,16-dial with rendemen amount of 0,00149 %.
SINTESIS TURUNAN ASETOFENON DARI 1-(4-ASETOKSIFENIL-3-METOKSI)-2-PROPANIL FORMAT Kusmiyati Kusmiyati; Sabirin Matsjeh; Jumina Jumina
Pharmaciana Vol 2, No 1 (2012): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (116.782 KB) | DOI: 10.12928/pharmaciana.v2i1.654

Abstract

The Synthesis of acetophenone derivative from 1-(4-acetoxyphenyl-3-methoxy)-2-propanyl formate through Fries Rearrangement in order to produceortho hidroxy acetophenone derivative as starting material of Flavanoid compound hasbeen done. The reaction of 1-(4-acetoxyphenyl-3-methoxy)-2-propanyl formate wasdone by heating at 120 °C for 3 hours under AlCl3, dichloromethane as the catalyst andsolvent, respectively. The structure of the compound was identified using Infra Redspectrometry (IR) dan GC-MS. Fries rearrangement of 1-(4-acetoxyphenil-3-methoxy)-2-propanyl formate produce 1-(2-hyidroxy-3-methoxy-5-propenyl)-acetophenone and 1-(2-hyidroxy-3-methoxy-5-propanyl)-acetophenone as sideproduct with product rendemen were 43.26% and 9.48%, respectively.
Co-Authors Jumina Jumina Nurfina Aznam Sabirin Matsjeh Sri Handayani