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PENINGKATAN SISTEM IMUN OLEH KOMBINASI EKSTRAK ETANOL DAUN AWAR – AWAR (Ficus septica burm. F) DAN EKSTRAK ETANOL DAUN KELOR (Moringa oleifera) SEBAGAI KO-KEMOTERAPI KANKER PADA TIKUS PUTIH BETINA GALUR SPRAGUE DAWLEY YANG DIINDUKSI DOKSORUBISIN Rizka Angerti Anovia; Dewi Indah Sari; Annisa Hardikasari Yazin; Ulfa Ismayani; Endang Darmawan
Pharmaciana Vol 5, No 2 (2015): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2663.276 KB) | DOI: 10.12928/pharmaciana.v5i2.2145

Abstract

Use of the drug doxorubicin for cancer therapy causes decreasing of immune system reported. Leaves of Ficus septica Burm. F and leaves of Moringa oleifera as immunostimulatory agents. The purpose of this study, among others, determine the combined effects of ethanol extract of Ficus septica Burm. F leaves and ethanol extract of Moringa oleifera leaves as co-chemotherapy for in female rats Sprague Dawley strain induced doxorubicin. Eighteen Sprague Dawley rats were divided into six treatment groups, normal group was given 0.9% NaCl 10ml / kgBB, positive control group were given by doxorubicin with dose of 4.67 mg / kgBB, single-dose treatment group were each given ethanol extract of Ficus septica Burm F leaves dose of 750 mg / kgBB and ethanol extract of Moringa oleifera leaves 500 mg / kgBB, treatment groups were given by combination of ethanol extract Ficus septica Burm. F leaves and Moringa oleifera leaves with a dose of 1.25 g / kgBB and a dose of 1 , 75 g / kgBB. treatment carried out for 7 days. On days 1 and 4 of each treatment groups except the normal group induced by doxorubicin 4.67 mg / kgBB intramuscularly. Blood sampling performed on day 0 and 7 th for lymphocytes CD3+ and lymphocytes CD8+ test. The results showed that the combination of ethanol extract Ficus septica burm. F leaves and Moringa oleifera leaves dose of 1.25 g / kgBB and the dose of 1.75 g / kgBB can enhanched immune system relative small which was not statistically significantly different (p> 0.05). However, a single dose of ethanol extract Moringa oleifera leaves dose of 500 mg/kg have immunostimulatory activity as lymphocytes CD3+ and lymphocytes CD8+ were more effective than a single dose of ethanol extract of Ficus septica Burm. F leaves dose of 750 mg/kgBB.
APLIKASI TRICHOKOMPOS TANDAN KOSONG KELAPA SAWIT TERHADAP PERTUMBUHAN BIBIT TANAMAN KAKAO (Theobroma cacao L.) Ulfa Ismayani; Nurbaiti Nurbaiti
Jurnal Online Mahasiswa (JOM) Bidang Pertanian Vol 4, No 2 (2017): Wisuda Oktober Tahun 2017
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Pertanian

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Abstract

The research aims to study the effect and to obtain the best dose of Trichokompos TKKS on the growth of cocoa seeds (Theobroma cacao L.). Research has been conducted at the Experimental Farm of the Faculty of Agriculture, Riau University. This study was conducted from June 2016 to September 2016. This research was experimental research by using Completely Randomized Design (CRD), which consisted of 5 TKKS trichokompos treatments, consisted of: 0 g/5 kg soil (T0), 25 g/5 kg soil (T1), 50 g/5 kg soil (T2),     75 g/5 kg soil (T3) and 100 g/5 kg soil (T4). Each treatment was repeated 4 times , in order to obtain 20 unit experiments which consist of 3 seeds, in which 2 seeds as sample plants and it obtained 60 plant seeds. The observed parameters were a height plant, stem diameter, number of leaves, root shoots ratio and dry weight. Data were analyzed using analysis of variance and the mean of each treatment was tested with Duncan’s New Multiple Range Test at 5 % level. The result of this research showed that the giving of trichokompos TKKS gave significant result towards all of observation parameters. Based on the result, the giving of trichokompos TKSS with dose 75 g/5 kg soil was better to improve the growth of cacao seeds. Keywords : the growth of, cacao seedlings, Trichokompos TKKS.