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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice)
Anton Bahtiar
Fakultas Farmasi, Universitas Indonesia
Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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FORMULASI GEL MENGGUNAKAN SERBUK DAGING IKAN HARUAN (Channa striatus) SEBAGAI PENYEMBUH LUKA Dina Rahmawanty; Effionora Anwar; Anton Bahtiar
Media Farmasi: Jurnal Ilmu Farmasi Vol 11, No 1: Maret 2014
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (4147.172 KB) | DOI: 10.12928/mf.v11i1.1395

Abstract

Daging  ikan  haruan  (Channa  striatus) dipercaya  dapat  digunakan  untuk menyembuhkan  luka  karena  mengandung  protein,  asam  amino esensial,  lemak dan  asam  lemak  yang  berperan  dalam  proses  penyembuhan  luka.  Tujuan  dari penelitian  ini  ialah  membuat  gel  yang mengandung  serbuk  daging  ikan  haruan sebagai penyembuh luka. Pada penelitian ini digunakan serbuk daging ikan haruan (Channa striatus) sebagai zat aktif sebanyak 1 gram pada formula 1 dan 2 gram pada  formula  2.  Serbuk  daging  ikan  haruan  dibuat  suspensi  dengan  ukuran partikel nanometer dengan metode gelasi ionik menggunakan kitosan dan natrium tripolifosfat,  kemudian  dibuat  menjadi  bentuk  sedian  gel  dengan  menggunakan gelling agent HPMC. Suspensi yang dihasilkan dilakukan karakterisasi fisika dan kimia. Hasil karakterisasi suspensi formula 1 dan formula 2 adalah sebagai berikut :  ukuran  partikel  berturut-turut  491,8  -  665,5  nm,  481,8 - 828,1  nm; indeks polidispersitas 0,512, 0,456; nilai potensial zeta (+)29,15mV, (+)29,35mV; kedua formula  mempunyai  partikel  berbentuk  sferis.  Sediaan  gel  yang  dihasilkan dievaluasi  aktivitas penyembuhan  luka  secara  in  vivo.  Dari hasil  uji  in  vivo sediaan gel serbuk daging ikan haruan dapat digunakan sebagai penyembuh luka. Kata  Kunci:  gel,  gelasi  ionik,  haruan  (Channa  striatus),  kitosan,  natrium tripolifosfat, luka.
ANALYSIS OF THE EFFECTIVENESS OF COUNSELING AND POSTER TOWARDS ADHERENCE AND THERAPEUTIC OUTCOME ON HYPERTENSIVE PATIENTS Risani Andalusia Putri; Retnosari Andrajati; Anton Bahtiar
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 3, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.109

Abstract

Although the number of pharmacists in primary health care is limited, counseling is very important. The Government obligates primary health care to use poster as a health promotion method. In this study, counseling and poster were used to inform patients about hypertension and its therapy. The objective of this study was to compare the influence of counseling and poster towards adherence and therapeutic outcome on hypertensive patients in Bakti Jaya Primary Care, Depok. Research was conducted by quasi experimental using non-equivalent control group design. Samples were hypertensive patients at Bakti Jaya Public Health Care Depok collected from March to May 2012. Samples were divided into two groups i.e. counseling and poster groups. In the first group, pharmacist gave counseling to the patients and in the other group, the patients were only given poster. Patient’s adherence and blood pressure as therapeutic outcome were measured before (pre test) and after intervention (post test). Patient’s adherence was measured using Morisky Medication Adherence Scale (MMAS-8) questionnaire. This study showed that counseling enhanced adherence (P=0.000) and decreased systolic and diastolic blood pressure (P=0.010 and P=0.018), whereas poster only increased adherence (P=0.028). The differences of MMAS-8 score between counseling and poster group were significantly different (P=0.017), and the decreasing of systolic and diastolic blood pressure between counseling and poster group were not significantly different (P=0.170 and P=0.410).Keywords : Adherence, Hypertension, Counseling, Poster
DRUG RELATED PROBLEMS EVALUATION OF CHRONIC KIDNEY DISEASE PATIENTS IN INPATIENT DEPARTMENT OF FATMAWATI GENERAL HOSPITAL Lusi Indriani; Anton Bahtiar; Retnosari Andrajati
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 3, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.99

Abstract

The use of drugs in patients with decreased renal function allows the occurrence of drug related problems. Pharmacist has responsibility to identify and to prevent drug related problems. This study was proposed to evaluate drug related problems in chronic kidney disease patients in Inpatient Department of Fatmawati General Hospital. It was descriptive analitic study with prospectively approach. The primary data was obtained by identifying drug related problems. The secondary data was taken from medical record of chronic kidney disease patients such as: age, sex, the stage of chronic kidney disease, comorbidity, and drug therapy. This study took place in Inpatient Department of Fatmawati General Hospital during the period of January to March 2012. Univariate analysis had done to obtain description of frequency and proportion of research variables such as the patient characteristics who received drug therapy (age, sex, the stage of chronic kidney disease, and comorbidity), the drug therapy characterictics that evaluated based on the number and type of drug therapy and drug related problems. Bivariate analysis of the Spearman correlation test was taken to evaluate whether there was correlation beetwen confounding variables and incident of drug related problems. The evaluation was taken in 40 chronic kidney disease patients with 377 number of drugs. The number of drug related problems was 98 issues (25.99% of prescribing drugs). Type of drug related problems were not optimal effect of drug treatments 62.24%, the incidence of non-allergic adverse drug events 20.41%, and the incidence of toxic adverse drug-events 17.35%. The confounding variables that significantly influence the incidence of drug related problems were comorbidities (r= 0.385; p= 0.014), and the number of drugs (r= 0.604; p= 0.000).Keywords: drug related problems, chronic kidney disease, Fatmawati General Hospital
Co-Authors Dina Rahmawanty Effionora Anwar Lusi Indriani Retnosari Andrajati Risani Andalusia Putri