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Ni Komang Ayu Kumala Dewi
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Chemistry

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UJI AKTIVITAS ANTIBAKTERI FRAKSI KULIT BATANG NANGKA I Made Dira Swantara; Ida Bagus Gede Darmayasa; Ni Komang Ayu Kumala Dewi
Jurnal Kimia (Journal of Chemistry) Vol. 5, No. 1 Januari 2011
Publisher : Program Studi Kimia, FMIPA, Universitas Udayana (Program of Study in Chemistry, Faculty of Mathematics and Natural Sciences, Udayana University), Bali, Indonesia

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Abstract

This research aims to isolate and identify antibacterial compounds in jackfruit bar husk (Artocarpus heterophyllus, Lam.). 735.55 gramc of jackfruit bar husk yielded 500,25 grams of crude methanol.extract. The methanol extract was fractionated using petroleum ether, ethyl acetate and of n-butanol and then evaporated to yield crude extract of ethyl acetate 4.11 grams of petroleum ether (yellowish), 2.11 grams of ethyl acetate extract (brownish), and 1.17 grams of n-butanol (dark green).Bioactivitigs tests to Staphylococcus aureus and Eschericia coli showed that ethyl acetate extract had the largest inhibition zone. The purification of ethyl acetate extract with column chromatography resulted a faction which was antibacterial active (faction C).Identification of faction C using Gas Chromatography Mass Spectroscopy showed 3 compounds namely methyl hexadecanoate, dioctyl hexadioate, and dioctyl-1,2-benzene dicarboxylate.
Co-Authors I Made Dira Swantara Ida Bagus Gede Darmayasa