Articles
Postradical Hysterectomy Survival Rate in Early Stage Cervical Cancer Patients
Yeremia, Wesley;
Rarung, Max;
Laihad, Bismarck J
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No.3, July 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology
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Objective: Determining the survival rate of early stage cervical cancer
patients after radical hysterectomy.
Method: A retrospective cohort study was conducted on 24 earlystage
cervical cancer patients who had performed radical hysterectomy
in Prof. dr. R.D. Kandou Hospital Manado during the period
between January 2008 and December 2010. We used Kaplan-Meier
methods to observe the survival rate.
Result: The mean age of patients in this study was 47.8 (33-63)
years old with a median of 45 years old. The largest proportion was
less than 50 years old (66.7%) and stage IIA cervical cancer (66.7%)
as the severity of cancer. Most histopathology type was the squamous
cell carcinoma (50.0%). About 70.8% patients did not have
lymph nodes metastasis and 62.5% patients did not receive adjuvant
therapy. This study revealed that 1-year, 2-year, 3-year, 4-year, and
5-year survival rate were 100.0%, 100.0%, 95.8%, 83.0%, 70.8%;
respectively.
Conclusion: The survival rate of early stage cervical cancer afte[Indones J Obstet Gynecol 2016; 4-3: 164-169]
Keywords: cervical cancer, radical hysterectomy, survival rate
Neutrophil and Platelet to Lmphocyte Ratio in Ovarian Malignancy
Utama, Francesca;
Tendean, Hermie;
Laihad, Bismarck J
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 1, January 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology
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DOI: 10.32771/inajog.v5i1.467
Objective: To determine the sensitivity and specificity of neutrophil
- lymphocyte ratio compared with platelet - lymphocyte ratio in
predicting ovarian malignancies.
Methods: This was an observational analytic study with diagnostic
test design on 37 ovarian tumor patients who were planned to
perform laparotomy in Prof. Dr. R.D. Kandou Hospital Manado and
network hospitals in Manado from March to May 2016. We took
blood samples to assess the complete blood count.
Results: During the period, we obtained the mean age of 28.1 years
old (range 18-71 years old). A total of 13 samples showed
malignancy which the cystadenocarcinoma mucinosum (27.0%) as
the most common histopathological types. Sensitivity and specificity
value of neutrophil - lymphocyte ratio were 92.3% and 95.8% with
2.47 as the cut-off point. Meanwhile, the sensitivity and specificity
of platelet - lymphocyte ratio were 61.5% and 75.0% with 152.86
as cut-off point.
Conclusion: Both neutrophil - lymphocyte ratio and platelet -
lymphocyte ratio are associated with ovarian malignancy. The
sensitivity and specificity of neutrophil - platelet ratio show better
prediction for ovarian malignancies.
[Indones J Obstet Gynecol 2017; 5-1: 55-59]
Keywords: neutrophil - lymphocyte ratio, ovarian cancer, platelet -
lymphocyte ratio
Endothelin1 Levels in Pregnant Women with Severe Preeclampsia and Normal Pregnant Women
Wijaya, Yosiana;
Wantania, John JE;
Laihad, Bismarck J
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 2, April 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology
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DOI: 10.32771/inajog.v5i2.523
Objective: To determine the ratio of serum endothelin-1 levels between severe preeclampsia and normotensive pregnancy.
Methods: Observational analytic study using cross-sectional. Sixteen woman with normal pregnancy and sixteen others with severe preeclampsia who met the inclusion and exclusion criteria, were tested for ET-1. The serum was analyzed at Prodia Laboratory, Manado. The ET-1 level was examined using ELISA (R&D Systems, Inc., Minneapolis, MN 55413, USA). The data obtained was analyzed using SPSS software version 20.0.and discussions were held using the existing literature theory.
Results: The mean and median levels of endothelin-1 plasma in patients with severe preeclampsia is 2:46 ± 1:44 pg/ml, 1:09 ± 0:26 pg/ml, whereas in normotensive pregnancy is 1:03 ± 0:26 pg/ml,
1.95 ± 1:44 pg/ml with p < 0:05 (0000).
Conclusion: There was a significant difference between endothelin- 1 level in severe preeclampsia and normotensive pregnancies.
[Indones J Obstet Gynecol 2017; 5-2: 77-82]
Keywords: endothelin-1, normotensive, preeclampsia
Bladder Function after Hysterectomy
Wijaya, Johanna;
Tendean, Hermie;
Laihad, Bismarck J
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No. 2, April 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology
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DOI: 10.32771/inajog.v4i2.83
Objective: To determine the effect of hysterectomy on bladder function
pre- and post-radical hysterectomy in early stage of cervical
cancer.
Method: This study was a pre-post intervention study. Data were
collected through questionnaires from women who had radical hysterectomy
and total hysterectomy in Prof. Dr. R. D. Kandou Manado
general hospital and other networking hospitals since January 1st,
2014 to November 31st, 2014. We analyzed the data using Wilcoxon
and Mann-Whitney statistical test.
Result: There were each 18 respondents for the radical and total
hysterectomy group in Prof. Dr. R. D. Kandou general hospital and
networking hospitals. The age distribution of radical hysterectomy
was 41-45 years old for 44.4%. The parity was dominated by second
parity for 38.8%. In pre- and post-surgery, there were significant differences
for urinary incontinence disorder (p=0.003), emptying disorder
(p=0.008), urinary pain (p=0.034), and total urinary disorder
(p=0.001). While, between radical and total hysterectomy, there was
no significant difference in bladder function (p>0.05).
Conclusion: There is an association before and after surgery to urinary
function. However, there is no association between the radical
and total hysterectomy group.
[Indones J Obstet Gynecol 2016; 4-2: 97-100]
Keywords: bladder function, cervical cancer, radical hysterectomy
Gynecology Cancer in Relationship with Obesity
Rauw, Gracia M R G;
Laihad, Bismarck J;
Affandi, Biran
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No. 1, January 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology
Show Abstract
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DOI: 10.32771/inajog.v4i1.68
Objective: To know the relationship between obesity and gynecology
cancer.
Method: This study use case control study design for 250 gynecology
patients (125 controls and 125 cases) in Prof. Dr. R. D. Kandou
Manado Hospital from 1 July to 30 November 2015. The data was
collected by measuring Body Mass Index (BMI) and filing out selfadministered
questioners.
Result: From the 250 subjects, the study group (125 subjects), 72
subjects have obesity (57.6%) and 97 subjects have multiple parities
(77.6%) with 58 subjects diagnosed with cervical cancer (46.4%). In
the control group (125 subjects), 71 subjects have normal weight
(56.8%) and 67 subjects have multiple parities (53.6%) with 64 subjects
diagnosed with ovarium cysts (51.2%). Using multivariate logistic
regression, the overweight and obese subjects have 7 folds
higher risk to develop gynecology cancer compared to those with
normal or underweight subjects. Those with multiple parities and
grande multipara subjects have 3 folds higher risk to develop gynecology
cancer compared with those who are nullipara and primipara.
Conclusion: A significant correlation is found between obesity and
gynecology cancer using multivariate logistic regression analysis
(p=0.000, OR=6.9 (95% CI = 3.62-13.13).
[Indones J Obstet Gynecol 2016; 1: 23-30]
Keywords: gynecology cancer, multiple parities, obesity
Gynecology Cancer in Relationship with Obesity
Rauw, Gracia M R G;
Laihad, Bismarck J;
Affandi, Biran
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No. 1, January 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology
Show Abstract
|
Download Original
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Original Source
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Check in Google Scholar
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Full PDF (67.324 KB)
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DOI: 10.32771/inajog.v4i1.68
Objective: To know the relationship between obesity and gynecology
cancer.
Method: This study use case control study design for 250 gynecology
patients (125 controls and 125 cases) in Prof. Dr. R. D. Kandou
Manado Hospital from 1 July to 30 November 2015. The data was
collected by measuring Body Mass Index (BMI) and filing out selfadministered
questioners.
Result: From the 250 subjects, the study group (125 subjects), 72
subjects have obesity (57.6%) and 97 subjects have multiple parities
(77.6%) with 58 subjects diagnosed with cervical cancer (46.4%). In
the control group (125 subjects), 71 subjects have normal weight
(56.8%) and 67 subjects have multiple parities (53.6%) with 64 subjects
diagnosed with ovarium cysts (51.2%). Using multivariate logistic
regression, the overweight and obese subjects have 7 folds
higher risk to develop gynecology cancer compared to those with
normal or underweight subjects. Those with multiple parities and
grande multipara subjects have 3 folds higher risk to develop gynecology
cancer compared with those who are nullipara and primipara.
Conclusion: A significant correlation is found between obesity and
gynecology cancer using multivariate logistic regression analysis
(p=0.000, OR=6.9 (95% CI = 3.62-13.13).
[Indones J Obstet Gynecol 2016; 1: 23-30]
Keywords: gynecology cancer, multiple parities, obesity
Bladder Function after Hysterectomy
Wijaya, Johanna;
Tendean, Hermie;
Laihad, Bismarck J
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No. 2, April 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (81.688 KB)
|
DOI: 10.32771/inajog.v4i2.83
Objective: To determine the effect of hysterectomy on bladder function
pre- and post-radical hysterectomy in early stage of cervical
cancer.
Method: This study was a pre-post intervention study. Data were
collected through questionnaires from women who had radical hysterectomy
and total hysterectomy in Prof. Dr. R. D. Kandou Manado
general hospital and other networking hospitals since January 1st,
2014 to November 31st, 2014. We analyzed the data using Wilcoxon
and Mann-Whitney statistical test.
Result: There were each 18 respondents for the radical and total
hysterectomy group in Prof. Dr. R. D. Kandou general hospital and
networking hospitals. The age distribution of radical hysterectomy
was 41-45 years old for 44.4%. The parity was dominated by second
parity for 38.8%. In pre- and post-surgery, there were significant differences
for urinary incontinence disorder (p=0.003), emptying disorder
(p=0.008), urinary pain (p=0.034), and total urinary disorder
(p=0.001). While, between radical and total hysterectomy, there was
no significant difference in bladder function (p>0.05).
Conclusion: There is an association before and after surgery to urinary
function. However, there is no association between the radical
and total hysterectomy group.
[Indones J Obstet Gynecol 2016; 4-2: 97-100]
Keywords: bladder function, cervical cancer, radical hysterectomy
Postradical Hysterectomy Survival Rate in Early Stage Cervical Cancer Patients
Yeremia, Wesley;
Rarung, Max;
Laihad, Bismarck J
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No.3, July 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology
Show Abstract
|
Download Original
|
Original Source
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Check in Google Scholar
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Full PDF (138.261 KB)
|
DOI: 10.32771/inajog.v4i3.441
Objective: Determining the survival rate of early stage cervical cancer
patients after radical hysterectomy.
Method: A retrospective cohort study was conducted on 24 earlystage
cervical cancer patients who had performed radical hysterectomy
in Prof. dr. R.D. Kandou Hospital Manado during the period
between January 2008 and December 2010. We used Kaplan-Meier
methods to observe the survival rate.
Result: The mean age of patients in this study was 47.8 (33-63)
years old with a median of 45 years old. The largest proportion was
less than 50 years old (66.7%) and stage IIA cervical cancer (66.7%)
as the severity of cancer. Most histopathology type was the squamous
cell carcinoma (50.0%). About 70.8% patients did not have
lymph nodes metastasis and 62.5% patients did not receive adjuvant
therapy. This study revealed that 1-year, 2-year, 3-year, 4-year, and
5-year survival rate were 100.0%, 100.0%, 95.8%, 83.0%, 70.8%;
respectively.
Conclusion: The survival rate of early stage cervical cancer afte[Indones J Obstet Gynecol 2016; 4-3: 164-169]
Keywords: cervical cancer, radical hysterectomy, survival rate
Neutrophil and Platelet to Lmphocyte Ratio in Ovarian Malignancy
Utama, Francesca;
Tendean, Hermie;
Laihad, Bismarck J
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 1, January 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (130.59 KB)
|
DOI: 10.32771/inajog.v5i1.467
Objective: To determine the sensitivity and specificity of neutrophil
- lymphocyte ratio compared with platelet - lymphocyte ratio in
predicting ovarian malignancies.
Methods: This was an observational analytic study with diagnostic
test design on 37 ovarian tumor patients who were planned to
perform laparotomy in Prof. Dr. R.D. Kandou Hospital Manado and
network hospitals in Manado from March to May 2016. We took
blood samples to assess the complete blood count.
Results: During the period, we obtained the mean age of 28.1 years
old (range 18-71 years old). A total of 13 samples showed
malignancy which the cystadenocarcinoma mucinosum (27.0%) as
the most common histopathological types. Sensitivity and specificity
value of neutrophil - lymphocyte ratio were 92.3% and 95.8% with
2.47 as the cut-off point. Meanwhile, the sensitivity and specificity
of platelet - lymphocyte ratio were 61.5% and 75.0% with 152.86
as cut-off point.
Conclusion: Both neutrophil - lymphocyte ratio and platelet -
lymphocyte ratio are associated with ovarian malignancy. The
sensitivity and specificity of neutrophil - platelet ratio show better
prediction for ovarian malignancies.
[Indones J Obstet Gynecol 2017; 5-1: 55-59]
Keywords: neutrophil - lymphocyte ratio, ovarian cancer, platelet -
lymphocyte ratio
Endothelin1 Levels in Pregnant Women with Severe Preeclampsia and Normal Pregnant Women
Wijaya, Yosiana;
Wantania, John JE;
Laihad, Bismarck J
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 2, April 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (101.959 KB)
|
DOI: 10.32771/inajog.v5i2.523
Objective: To determine the ratio of serum endothelin-1 levels between severe preeclampsia and normotensive pregnancy.
Methods: Observational analytic study using cross-sectional. Sixteen woman with normal pregnancy and sixteen others with severe preeclampsia who met the inclusion and exclusion criteria, were tested for ET-1. The serum was analyzed at Prodia Laboratory, Manado. The ET-1 level was examined using ELISA (R&D Systems, Inc., Minneapolis, MN 55413, USA). The data obtained was analyzed using SPSS software version 20.0.and discussions were held using the existing literature theory.
Results: The mean and median levels of endothelin-1 plasma in patients with severe preeclampsia is 2:46 ± 1:44 pg/ml, 1:09 ± 0:26 pg/ml, whereas in normotensive pregnancy is 1:03 ± 0:26 pg/ml,
1.95 ± 1:44 pg/ml with p < 0:05 (0000).
Conclusion: There was a significant difference between endothelin- 1 level in severe preeclampsia and normotensive pregnancies.
[Indones J Obstet Gynecol 2017; 5-2: 77-82]
Keywords: endothelin-1, normotensive, preeclampsia