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All Journal PROSIDING SEMINAR KIMIA Jurnal Pengabdian Masyarakat Kesehatan Indonesia
Lilis Febriyanti
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Chemistry Dentistry Education Health Professions Medicine & Pharmacology Public Health

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ANALISIS KUANTITATIF FENOL TOTAL DAN UJI AKTIVITAS ANTIOKSIDAN EKSTRAK AIR, METANOL, DAN N-HEKSAN DAUN PEPAYA DENGAN METODE DPPH Lilis Febriyanti; Adinda Citra
PROSIDING SEMINAR KIMIA Prosiding SNKT Himpunan Mahasiswa Kimia FMIPA UNMUL 2021
Publisher : PROSIDING SEMINAR KIMIA

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Abstract

Pepaya (Carica papaya L.) merupakan tanaman yang berasal dari Amerika tropis. Di Indonesia, tanaman pepaya dapat tumbuh mulai dari dataran rendah hingga dataran tinggi, bagian daunnya memiliki banyak komponen bioaktif salah satunya adalah senyawa fenol. Senyawa fenol telah dibuktikan memiliki aktivitas antioksidan yang dapat menghambatdan menangkal radikal bebas. Radikal bebas menyebabkan kerusakan sel pada tubuh manusia. Tujuan dari penelitian ini adalahmenetapkan kadar fenol total dan mengetahui aktivitas antioksidan dari ekstrakair, metanol, dan n-heksan pada daun pepaya (Carica papaya L.). Penetapan kadarfenol total diukur dengan metode Folin-Ciocalteu. Hasil penelitianmenunjukan ekstrak metanol memiliki kadar fenol tertinggi sebesar 50,1818 mgGAE/g dan ekstrak n-heksan memiliki kadar fenol total terendah sebesar 3,1788 mgGAE/g sedangkan ekstrak air memiliki kadar fenol total sebanyak 21,0303 mgGAE/g. Hasil pengujian aktivitas antioksidan diketahui bahwa nilai IC50 ekstrak air,metanol, dan daun pepaya secaraberturut-turut sebesar 843,923 ppm; 495,618 ppm; dan 1.278,01 ppm. Hal ini menunjukkan bahwa ekstrak air, metanol, dan n-heksan daun pepaya mempunyai aktivitas antioksidan yang sangat lemah.Kata kunci: daun pepaya, fenol total, antioksidan, air, metanol, n-heksan, Folin-Ciocalteu.
PEMBERDAYAAN MASYARAKAT DALAM PENGGUNAAN JERUK NIPIS SEBAGAI ANTIHIPERLIPIDEMIA DI KELURAHAN COBLONG KECAMATAN CIPAGANTI Lilis Febriyanti; Elvi Trinovani
Jurnal Pengabdian Masyarakat Kesehatan Indonesia Vol. 1 No. 1 (2022): Jurnal Pengabdian Masyarakat Kesehatan Indonesia
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jpmki.v1i1.976

Abstract

Hypercholesterolemia has become a health problem in both developed and developing countries. The highest prevalence of hypercholesterolemia is in Europe, followed by America, and the lowest is in Southeast Asia. According to data from the World Health Organization (WHO) (2015), hypercholesterolemia has caused a third of the number of ischemic heart disease. Meanwhile, deaths reached 2.6 million people (4.5% of total deaths) and 29.7 million people experienced the inability to live a normal life. The results showed that lime (Citrus Aurantifolia) was beneficial for lowering total blood cholesterol levels at a dose of 1.5 ml/KgBB. This is because lime juice is rich in Vitamin C which is a natural anti-oxidant, which works by reducing oxidative stress, inhibiting carbohydrate digestion and inhibiting fat transport along the walls of the small intestine, thereby lowering cholesterol in the blood. So the PKM Pharmacy team did community service with the title Community Empowerment in the Use of Lime Fruit as Antihypercholesterolemia in Coblong Village, Cipaganti District, Bandung City. From the results of this community service, it was found that there was an increase in knowledge, attitudes and skills as well as an increase in the health of community partners with outreach activities from the PKM proposer team at the Bandung Health Polytechnic Department of Pharmacy regarding the use of lime fruit to overcome hypercholesterolemia problems, checking the community's total blood cholesterol levels before and after PKM program, the practice of making traditional drinks from lime fruit plants for health benefits.
PEMBERDAYAAN MASYARAKAT DALAM PENGGUNAAN TANAMAN SELEDRI SEBAGAI ANTIHIPERTENS DI MARGALUYU KELURAHAN MARGASARI, KECAMATAN BUAH BATU, BANDUNG.: PEMBERDAYAAN MASYARAKAT DALAM PENGGUNAAN TANAMAN SELEDRI SEBAGAI ANTIHIPERTENS DI MARGALUYU KELURAHAN MARGASARI, KECAMATAN BUAH BATU, BANDUNG. Lilis Febriyanti; Yayat Sudaryat; Irvan Herdiana
Jurnal Pengabdian Masyarakat Kesehatan Indonesia Vol. 1 No. 2 (2022): Jurnal Pengabdian Masyarakat Kesehatan Indonesia
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jpmki.v1i2.1251

Abstract

  n the world, hypertension is ranked third as a risk factor for death. In 2025, the increase in cases of hypertension, especially in developing countries, is estimated to be around 80% of the 639 million cases in 2000 or around 1.15 billion cases (Pusparini, 2015). In botany, celery leaves are said to contain Apigenin which can prevent constriction of blood vessels and Phthalides which can relax artery muscles or relax blood vessels. These substances regulate blood flow, allowing blood vessels to dilate and reduce blood pressure. Based on this, it is necessary to empower the community in the use of celery plants to overcome hypertension problems, which is carried out in the Community Service program in the PKM scheme with partners being PKK Cadres RW 09 in Margasari Village, Buah Batu District, Bandung. This PKM activity took place in seven activities, namely: Checking participants' blood pressure before being treated with celery plants, conducting pre-tests on participants before counseling was carried out, weighing celery plants to be distributed to each participant so they could be self-medicating at home, conducting lectures and discussions about hypertension, antihypertensive chemical drugs, and the use of antihypertensive celery plants, demonstrations of making herbal celery drinks which are efficacious as antihypertensives and distributing drinks to participants, carrying out post tests, and checking participants' blood pressure after being treated with celery plants for 3 days . The solution offered is an increase in the knowledge, attitudes, and skills of the PKM partners as indicated by an increase in the post-test scores when compared to the pre-test scores. In addition, there was also an increase in the degree of public health with a decrease in blood pressure, especially in participants who suffered from hypertension after being treated with celery leaves.
Co-Authors Adinda Citra Elvi Trinovani, Elvi Irvan Herdiana Yayat Sudaryat