Article Per Year (5 Year)
p-Index From 2020 - 2025
0
P-Index
This Author published in this journals
All Journal MPI (Media Pharmaceutica Indonesiana)
Babtista Merchyta Winarjo
Faculty of Pharmacy, University of Surabaya Jl. Raya Kalirungkut Surabaya 60294
Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Formulation and pH-Physical Stability Evaluation of Gel and Cream of Plantago major Leaves Extract Kartini Kartini; Babtista Merchyta Winarjo; Endang Wahyu Fitriani; Ridho Islamie
MPI (Media Pharmaceutica Indonesiana) Vol. 1 No. 3 (2017): JUNE
Publisher : Fakultas Farmasi, Universitas Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (399.981 KB) | DOI: 10.24123/mpi.v1i3.330

Abstract

Plantago major has been widely used for wound healing. This activity is supported by empiricalas well as preclinical data. The aims of this study were to (1) formulate Plantago major leaves extracts(PMLE) into topical dosage forms i.e. creams and gels and; (2) evaluate the pH and physical stability of theproducts. The results showed that creams and gels of PMLE were able to maintain the pH, visual appearance,flow properties, droplet size, and type of emulsion under accelerated (40±2 °C; 75±5% RH for 1.5 months)as well as room temperature (27 °C; 85% RH for 1.5 months) stability testing conditions. However, viscosityof creams significantly changed under those conditions. Even though the viscosity of gels was unstableunder accelerated condition, it was stable under room temperature storage. It is concluded that PMLEcould be formulated into creams or gels dosage forms and further optimisation should be conducted.
Co-Authors Endang Wahyu Fitriani Islamie, Ridho Kartini Kartini