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All Journal journal of internal medicine E-Jurnal Medika Udayana E-Jurnal Udayana Medica The Indonesian Biomedical Journal Jurnal Penyakit Dalam Udayana International Journal of Retina ISM (Intisari Sains Medis) : Jurnal Kedokteran Eduvest - Journal of Universal Studies IJRETINA - International Journal of Retina
I Wayan Losen Adnyana
Division Of Hematology And Medical Oncology, Department Of Internal Medicine, Faculty Of Medicine, University Udayana, Prof IGNG Ngoerah Hospital, Bali, Indonesia
Aerospace Engineering Biochemistry, Genetics & Molecular Biology Computer Science & IT Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Social Sciences

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Journal : E-Jurnal Udayana Medica

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NEGATIVE CORRELATION BETWEEN LEUKOCYTE COUNT AND HIGH DENSITY LIPOPROTEIN IN TYPE 2 DIABETES MELLITUS PATIENTS IN SANGLAH GENERAL HOSPITAL, BALI Ni Luh Made Novi Ratnasari; Made Ratna Saraswati; I Wayan Losen Adnyana; I Wayan Sudhana
Bali Journal of Medical and Health Sciences vol 1,no 2(2017):volume 1 no 2 Mei 2017
Publisher : Faculty of Medicine, Udayana University

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Abstract

Type 2 diabetes mellitus (T2DM) is group with high cardiovascular disease (CVD) risk. Inflammation which is reflected by increasing leukocyte number, CRP, and lipid profile. Despite that, infection as one of diabetic complication commonly occurs in patient with T2DM. The dyslipidemia status reflected by lipid profile composition. So here, we aim to evaluate the relationship between leukocyte count with lipid profile to know the association between traditional and non-traditional risk factor of CVD in T2DM patient. The type of this research is cross sectional analytic research with 94 samples was enrolled into this study. The data is obtained initially by collecting from the quistionare and from laboratorium examination. Mean of samples’ age is 55 years and large number of patients had leukocytosis as reflected by high value of its mean (15.02±8.78 x 103/?L). We found that 56.4% of the subjects fall into worst category of glycemic control (HbA1C). Only 24.5% of the subjects had good glycemic control. Further evaluation showed that there were significant strong negative correlations between leukocyte count with HDL (r= -0.555; p=0.000). Inflammation which mainly related to infectious disease is common among T2DM patients which increase CVD risk by lowering HDL and worsening glycemic control.Keywords: Type 2 Diabetes Mellitus, lipid profile, leukocyte count
Co-Authors Agung Adi Nugroho, Agung Adi Anak Agung Gde Budhiarta Anggelia, Vivi Ari Andayani Ari Andayani Arundina Sanyoto Ayu, Nyoman Paramita Dharmayuda, Tjokorda Gede Fernanda Savitri Mega Pratistha Gede Sukrawan Hensen - I Gede Eddy Pramana Agustina I Gusti Bagus Aginda Dwi Pawana I Gusti Putu Suka Aryana I Made Bakta I Putu Budhiastra I Putu Budhiastra, I Putu I Wayan Sudhana Ketut Suega Made Paramita Wijayati MADE RATNA SARASWATI . Ni Luh Made Novi Ratnasari Ni Made Ayu Sintya D Nyoman Arya Shridewi Abhigamika Pratistha, Fernanda Savitri Mega Rena, Ni Made Renny A Wijayati, Made Paramita Winarto, Daniel