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Dwi Lestari Partiningrum
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HUBUNGAN ANTARA LAMA HIPERTENSI DAN GAMBARAN ELEKTROKARDIOGRAM HIPERTROFI VENTRIKEL KIRI DAN INFARK MIOKARD LAMA Almira Khansa; Dwi Lestari Partiningrum
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 7, No 2 (2018): JURNAL KEDOKTERAN DIPONEGORO
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (406.323 KB) | DOI: 10.14710/dmj.v7i2.21198

Abstract

Latar Belakang: Hipertensi adalah salah satu masalah kesehatan utama di masyaratakat. Hipertensi juga merupakan faktro risiko pernyakit kardiovaskular dan  bertanggung jawab atas separuh dari mortalitas penyakit kardiovaskular. Hipertensi yang berlangsung kronis secara klasik dikaitkan dengan hipertrofi ventrikel kiri tipe konsentris. Peningkatan ketebalan dinding ventrikel kiri (VK) memungkinkan terjadinya normalisasi tekanan dinding VK terhadap peningkatan tekanan darah. Sementara itu, hipertensi berperan penting terhadap kejadian infark miokard. Hipertensi sistolik dan diastolik meningkatkan risiko infark miokard dan semakin tinggi tekanan, semakin besar risikonya. Data tentang hubungan antara durasi hipertensi dan prevalensi penyakit jantung hipertensi masih belum diketahui secara luas.Tujuan: Menganalisis hubungan antara lama hipertensi dan elektrokardiogram (EKG) HVKi dan infark miokard lama.Metode: penelitian ini adalah penelitian observasional analitik dengan pendekatan crossectional. 44 pasien hipertensi yang berobat di RSUP Dr.Kariadi dipilih secara consecutive sampling, kemudian dilakukan pemeriksaan EKG, catatan medis, dan anamnesis. Data yang dikumpulkan adalah lama hipertensi, hasil EKG, jenis kelamin, riwayat merokok, diabetes mellitus (DM), hiperurisemia, obesitas (Index massa tubuh/IMT), dislipidemia (profil lipid), dan hiperurisemia (serum asam urat). Diagnosis EKG HVKi menggunakan kriteria Cornell. Diagnosis EKG infark miokard lama menggunakan gambaran Q patologisHasil: dari 44 subyek penelitian diperoleh enam belas pasien (36,4%) memiliki gambaran EKG infark miokard lama dan tujuh (15,9%) pasien positif gambaran EKG HVKi. 21 (47,7%) subyek lainnya negatif gambaran EKG HVKi dan infark miokard lama. Uji Mann Whitney menunjukkan tidak terdapat hubungan antara lama hipertensi dan gambaran EKG infark miokard lama (p=0,633). Uji Mann Whitney juga menunjukkan lama hipertensi tidak berhubungan dengan gambaran EKG HVKi (p = 0,584)Kesimpulan: dalam penelitian ini belum terbukti bahwa lama hipertensi mempengaruhi kejadian gambaran EKG infark miokard lama dan HVKi.
RIGHT VENTRICULAR AND PULMONARY HYPERTENSION IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND RESTRICTIVE LUNG DISEASE Valencia Fabiana; Dwi Lestari Partiningrum; Bernardus Parish Budiono; Fathur Nur Kholis
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 3 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (603.557 KB) | DOI: 10.14710/dmj.v9i3.27498

Abstract

Background: Chronic lung disease is frequently associated with lung vascular lesion. We evaluated the structural-functional related changes of right ventricle under CLD with or without PH at RSUP dr. Kariadi, Semarang. Methods: We studied patients at RSUP dr. Kariadi who underwent routine evaluation that included resting spirometry and echocardiography. Patients with either COPD or RLD were studied, exclusion were made for patients with valvular heart disease and congestive heart disease. This study was performed during May through June of 2019 (n = 20). PASP, RVD, RVWT, TAPSE and spirometry values were analyzed for the association between PASP and RVD, RVWT, TAPSE, TAPSE/PASP ratio and FVC, FEV1, FEV1/FVC. Results: Thirteen (65%) of 20 patients who underwent echocardiography and spirometry evaluation were male and their average age were 55 years old. Mean PASP was 49.30 mmHg (range 2–111 mmHg). Ninety five percents patients had restrictive spirometry and 5% patients had moderate-severe mixed spirometry. The majority of the population of the study sample is dominated by a very severe degree of restriction spirometry. Out of the 20 subjects, 15 subjects (75%) had a diagnosis of COPD and 10 subjects (50%) had a history of pulmonary TB. In this study, 75% subjects had right ventricular dilatation, 85% subjects had right ventricular hypertrophy, and 15% subjects had decreased right ventricular systolic function (low TAPSE). The majority of structural and functional abnormalities of the right heart are found on patients with very severe degree of restriction spirometry. There were 13 subjects (65%) pulmonary hypertension, with the most findings being severe pulmonary hypertension as many as 8 subjects (40%). As many as 14 subjects (70%) had high TAPSE / PASP ratio.Conclusions: PH prevalence in patients with CLD is significantly associated with spirometry values. PH severity degree in patients with CLD is not significantly associated with spirometry values.Key words: spirometry; pulmonary hypertension; right heart echocardiography.
Co-Authors Almira Khansa Bernardus Parish Budiono Fathur Nur Kholis Valencia Fabiana