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All Journal Jurnal Kedokteran Diponegoro JEPA (Jurnal Ekonomi Pertanian dan Agribisnis)
Nafisah Zahra
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Agriculture, Biological Sciences & Forestry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Environmental Science Medicine & Pharmacology Social Sciences

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HUBUNGAN ANTARA KADAR VITAMIN D DENGAN KADAR MALONDIALDEHID (MDA) PLASMA PADA LANSIA Nafisah Zahra; Andrew Johan; Dwi Ngestiningsih
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 8, No 1 (2019): JURNAL KEDOKTERAN DIPONEGORO
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (334.04 KB) | DOI: 10.14710/dmj.v8i1.23348

Abstract

Latar Belakang: Pada lanjut usia radikal bebas bertanggung jawab terhadap kerusakan tingkat sel dan jaringan terkait usia. Dalam beberapa dekade terakhir, beberapa penelitian telah menunjukkan bahwa vitamin D3 memiliki aktivitas antioksidan.Vitamin D3 telah dibuktikan sebagai antioksidan yang menghambat lipid yang diinduksi besi peroksidasi liposom otak.Vitamin D3 sistemik menekan lipid yang tinggi.Aktivitas peroksidasi diamati pada tikus kekurangan vitamin D3dimana terjadi peningkatan penanda stres oksidatif, salah satunya adalah malondialdehid (MDA).Selain itu, vitamin D3 telah dilaporkan mengurangi stres oksidatif dengan menaikkan pertahanan antioksidan sistem, termasuk kandungan glutation, glutation peroksidase, dan superokside dismutase pada astrosit dan di hati. Tujuan: untuk mengetahui hubungan antara kadar vitamin D dengan kadar MDA plasma pada lansia Metode: penelitian ini menggunakan design cross sectional dengan mengambil subyek secara consecutive samplingdari beberapa posyandu lansia di kota Semarang. Pemeriksaan kadar Vitamin D dilakukan dengan metode ELISA ,sedangkan pemeriksaan kadar MDA plasma dilakukan dengan metode TBARS. Hasil: terdapat hubungan yang signifikan antara kadar Vitamin D dengan kadar MDA plasma (p : 0,021) dengan nilai korelasi cukup (r : -0,364) hal ini menunjukkan semakin tinggi kadar Vitamin D pada lansia berkorelasi dengan menurunnya aktivitas peroksidasi lipid yang ditandai dengan menurunnya kadar malondialdehid (MDA) plasma. Kesimpulan: terdapat hubungan yang signifikan antara kadar Vitamin D dengan kadar MDA plasma pada lansiaKata Kunci: Lansia, Vitamin D, MDA, peroksidasi lipid.
PENERAPAN PERSAMAAN SIMULTAN PADA ANALISIS HUBUNGAN PRODUKSI PADI DAN KONSUMSI BERAS UNTUK MELIHAT KONDISI KETAHANAN PANGAN STUDI KASUS INDONESIA TAHUN 2024 Rahmad Fradani, Faisal Agymnastiar; Nafisah Zahra; Tenry Kusuma Astuti; Aulia Rahmi Al Muqorobbun; Nindya Faristanti; Laksmi Yustika Devi
Jurnal Ekonomi Pertanian dan Agribisnis Vol. 10 No. 2 (2026)
Publisher : Department of Agricultural Social Economics, Faculty of Agriculture, Brawijaya University

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Abstract

This study aims to analyse the simultaneous relationship between rice production and rice consumption in order to review Indonesia's food security conditions in 2024. The method used is Two Stage Least Squares (2SLS) in a simultaneous equation model, with secondary data from 34 provinces. The estimation results indicate that there is a simultaneous relationship between rice consumption and rice production. However, only rice consumption has been proven to have a significant effect on rice production. This means that an increase in rice consumption by the public drives an increase in rice production, while an increase in rice production does not directly affect the level of rice consumption by the public. Every 1% increase in consumption will drive rice production up by 0.114765%. Harvest area also has a significant effect, with a 1% increase in harvest area resulting in a 1.078499% increase in production. On the consumption side, only population density has a significant impact, increasing rice consumption by 0.441294%. The model has met the classical assumption tests and model validity, so the results can be trusted. These findings highlight the importance of maintaining a balance between consumption and production to support sustainable national food security.
Co-Authors Andrew Johan Aulia Rahmi Al Muqorobbun Dwi Ngestiningsih Laksmi Yustika Devi Nindya Faristanti Rahmad Fradani, Faisal Agymnastiar Tenry Kusuma Astuti