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All Journal Jurnal Kesehatan Lingkungan indonesia Universa Medicina Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Sugeng Juwono Mardihusodo
Balai Besar Penelitian dan Pengembangan Vektor dan Reservoir Penyakit Salatiga
Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Directly observed treatment increases drug compliance in lymphatic filariasis mass drug administration Rosanti, Tutik Ida; Mardihusodo, Sugeng Juwono; Artama, Wayan T.
Universa Medicina Vol 35, No 2 (2016)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2016.v35.119-127

Abstract

Backgroud. Mass drug administration (MDA) has been one of the strategies for lymphatic filariasis elimination. Since the start of implementation in 2011 in Pekalongan, no study on MDA acceptability has yet been done. The objectives of the study were to determine the microfilaria rate (mf rate) and the risk factors of drug compliance in the MDA program. MethodsA longitudinal study was conducted at Pabean region, Pekalongan City. There were 90 household heads as subjects, who were selected by proportional cluster random sampling. Microfilaria rate (mf rate) was determined by finger blood examination. Drug compliance was measured using questionnaires and observation sheets. Drug compliance observers, filariasis counseling participation, and presence of filariasis patients were factors influencing drug compliance. ResultsMf rate in 2015 was 1.35% and drug compliance rate was 86.80%. Reasons for failing to take drugs were fear of side effects (50%), refusals (25%), laziness (16.7%), and perceiving the drug to be useless (8.3%). The chi-square test shows a significant difference between the presence of drug compliance observer and compliance (p=0.006). Filariasis counseling participation and presence of filariasis patients did not show a significant difference with drug compliance (p= 0.986).ConclusionsFamilies as the source of observers was associated with increased filariasis drug compliance. It is therefore essential to address the issues linked to low compliance to make the program more efficient and achieve the goal of filariasis elimination.
Karakteristik Wilayah Sebagai Determinan Penyebaran Malaria di Kabupaten Jepara Raharjo, Mursid; Sutikno, Sutikno; Mardihusodo, Sugeng Juwono
Jurnal Kesehatan Lingkungan Indonesia Vol 2, No 1 (2003): APRIL 2003
Publisher : Master Program of Environmental Health, Faculty of Public Health, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jkli.2.1.6 - 11

Abstract

ABSTRACT Background : Malaria in Jepara district is inequitable distribution. This is very important object specially to evaluate the correlation between the  geographical characteristics and the Anopheles aconitus  densities as a vector of malaria. The other object  is the correlation between the climatic changes and malaria incidence. Method : Based on the malaria incidence the area are segregated in 3 class, High Case Incidence (HCI), Medium Case Incidence(MCI),  and Low Case Incidence (LCI). The next stratification was  based on topography, with the interval  of  0-25 m, 26 –50 m, 51-75 m, 76 – 100 m, and more than 100 m above sea level. Research was done in the wet and dry season. Correlation between dependent and independent variable analyses  by  the Pearson Product Moment, and determinant coefficient analyses  to conclude the determinant  variable Result :  The results of the research showed determinant coefficient of  geographical characteristics to Anopheles aconitus densities 94,9% (R2 =0,949), with the correlation coefficient  0,974. Gradually the partial  impact of the geographical characteristic to the Anopheles aconitus densities  were : 1. humidity 64,96% 2.waste water treatment 36,6%; 3. solid waste management 32,15%; 4. salinity 23,33%; 5. population density 19,18%; 6.air temperature 16,48%; 7. topography 11,56%; 8.  vegetation densities 5,2%, if the other parameter do not calculated. Conclusion: Jepara district have deferent geographical characteristic that  fluctuatively as  the season, and regulated Anopheles aconitus distribution. The determinant parameter are humidity (64,96%), waste water treatment (36,6%) solid waste management (32,15%); salinity (23,33%,), population density (19,18%) air temperature (16,48%), topography (11,56%)  vegetation densities 5,2%, if the other parameter do not calculated. The geographical characteristic compose the special zone as a Anopheles aconitus habitat.   Key word : Geographical characteristic,  Anopheles aconitus densities, determinant parameter.
Bancroftian Filariasis Transmission Parameters after the Fifth Year of Filiariasis Mass Drug Administration in Pekalongan City Rosanti, Tutik Ida; Mardihusodo, Sugeng Juwono; Artama, Wayan
Kesmas Vol. 12, No. 1
Publisher : UI Scholars Hub

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Abstract

Penelitian ini bertujuan untuk mengukur parameter parasitologi (microfilaria rate, kepadatan mikrofilaria), parameter imunologi (antigen prevalence) dan parameter entomologi (infection rate dan infective rate) pada tahun kelima pelaksanaan mass drug administration di Kelurahan Pabean Kota Pekalongan. Penelitian ini merupakan penelitian observasional dengan pendekatan potong lintang yang dilaksanakan pada bulan Juli sampai dengan Agustus 2015 di Kelurahan Pabean Kota Pekalongan. Microfilaria rate dan kepadatan mikrofilaria ditentukan dengan pemeriksaan darah jari pada 313 responden. Antigen prevalence ditentukan dengan mengukur antigen beredar menggunakan metode immunochromatographic test (ICT) Wuchereria bancrofti. Incective rate dan infection rate diukur dengan cara menemukan larva cacing filaria pada nyamuk hasil penangkapan nyamuk umpan orang. Hasil penelitian menunjukkan mf rate sebesar 0,32% dengan kepadatan mikrofilaria 167/mL darah, antigen prevalence pada hasil 0%, infection rate sebesar 0,06% dan infective rate sebesar 0%. Dapat disimpulkan bahwa pasca tahun kelima pengobatan massal filariasis di Kelurahan Pabean, Kota Pekalongan tidak lagi menjadi wilayah endemis filariasis dan parameter-parameter transmisi tidak berpotensi menimbulkan penularan. This study aimed to measure parasitology parameters (microfilariae rate, microfilariae density), immunology parameter (antigen prevalence), and entomology parameters (infection rate and infective rate) after the fifth year of mass treatment at Pabean Village, Pekalongan City. This study was an observational study with cross-sectional approach that was conducted in July to August 2015 in Pabean Subdistrict, Pekalongan City. The microfilaria rate and microfilariae density were determined by finger blood survey of 313 respondents. Meanwhile, the antigen prevalence was determined by calculating the circulating antigen using the immunochromatographic test (ICT) Wuchereria bancrofti method. Finally, the infective rate and infection rate were both explicitly defined by detecting filarial worm larvae in the mosquitoes of man biting mosquitos collection. The results showed that the mf rate was 0.32% with average microfilariae density of 167/mL blood, the antigen prevalence of the calculation was 0%, the infection rate was 0.06% and the infective rate was 0%. In conclusion, after the fifth year of mass treatment in Pabean Area, Pekalongan City, the area is no longer included into the filariasis-endemic areas and the transmission parameters has no potential in causing the filariasis spreading.
Co-Authors Artama, Wayan Melianus Salakory, Melianus Mursid Raharjo Soeyoko Soeyoko Sutanto Sutanto Sutikno Sutikno Tutik Ida Rosanti Wayan T. Artama