David B. Kamadjaja
Department Of Oral And Maxillofacial Surgery, Faculty Of Dental Medicine, Universitas Airlangga

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Closed reduction in the treatment of neglected mandibular fractures at the Department of Oral and Maxillofacial Surgery, Universitas Airlangga Olivia Jennifer Gunardi; Riska Diana; David Buntoro Kamadjaja; Ni Putu Mira Sumarta
Dental Journal (Majalah Kedokteran Gigi) Vol. 52 No. 3 (2019): September 2019
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v52.i3.p147-153

Abstract

Background: The mandible is one of the bones most affected by facial fractures commonly resulting from trauma to the face. The ultimate goal of treatment is to re-establish the pre-injury dental occlusion (bite), mandibular anatomy and jaw function of the patient. Treatment approaches range from conservative non-invasive management by ’closed’ reduction and immobilization using intermaxillary fixation (IMF) to the more invasive surgery-based ’open’ reduction incorporating an internal fixation approach. Purpose: The purpose of this case series was to describe the close reduction method as a form of treatment in cases of neglected mandibular fracture. Cases: Four cases of single or multiple mandibular fracture were presented. Case management: All of the cases were managed using a closed reduction method and IMF. Conclusion: A closed reduction method in this case series produced encouraging results and could be considered an alternative in the treatment of neglected mandibular fractures with displacement.
Degradation rate and weight loss analysis for freeze-dried, decellularized, and deproteinized bovine bone scaffolds Vidarta, Ramadhan Pramudya; Kamadjaja, David Buntoro; Danudiningrat, Coen Pramono; Amir, Muhammad Subhan; Rizqiawan, Andra; Yuliati , Anita; Darwis, Darmawan
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 1 (2025): March
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i1.p23-29

Abstract

Background: Mandibular defects, often caused by trauma, tumors, infections, and congenital issues, are commonly treated with bone grafts. Tissue engineering plays a crucial role in bone reconstruction, with scaffolds such as deproteinized bovine bone matrix (DBBM), freeze-dried bovine bone (FDBB), and decellularized FDBB (Dc-FDBB) being studied for their efficacy. Decellularization reduces the antigenic potential of FDBB. These scaffolds are designed to degrade within the body. Purpose: To analyze the weight loss and degradation rates of FDBB and Dc-FDBB materials, using DBBM as a control. Methods: This in vitro experimental study, conducted over 2 months, employed a cross-sectional approach to analyze the weight loss and degradation rates of FDBB, Dc-FDBB, and DBBM scaffolds in a simulated body fluid (SBF) solution. Results: Under dynamic immersion conditions, DBBM exhibited the highest daily weight loss at 0.741% and a degradation rate of 0.466 mg/cm²/day, followed by Dc-FDBB at 0.568% and 0.418 mg/cm²/day and FDBB at 0.525% and 0.385 mg/cm²/day. Under static immersion conditions, DBBM also showed the highest weight loss at 0.255%, with a degradation rate of 0.165 mg/cm²/day, followed by Dc-FDBB at 0.245% and 0.163 mg/cm²/day, and FDBB at 0.168% with a degradation rate of 0.126 mg/cm²/day. Significant differences were observed between scaffold groups (p = 0.000). Conclusion: DBBM, Dc-FDBB, and FDBB scaffolds meet the optimal requirements for tissue engineering materials based on their weight loss and degradation rates. DBBM demonstrated the highest values among the scaffolds analyzed.
Immuno-expression analysis of VEGF and CD34 related to histological types of mandibular ameloblastoma Pradana, Septian; Kamadjaja, David Buntoro; Danoediningrat, Coen Pramono; Sumarta, Ni Putu Mira; Amir, Muhammad Subhan; Rahayu, Retno Pudji; Bhagat, James Antony
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 2 (2025): June
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i2.p144-150

Abstract

Background: Increased expression of vascular endothelial growth factor (VEGF) and cluster of difference 34 (CD34) in ameloblastoma has been noted. Both proteins are markers of angiogenesis that play a role in supporting the growth of ameloblastoma. The existence of histopathological types of ameloblastoma allows for differences in behavioral and growth characteristics. Purpose: To evaluate the differences and correlation of VEGF and CD34 expression in histological types of ameloblastoma. Methods: This laboratory cross-sectional study uses total sampling from histological slides of mandibular ameloblastoma. Two observers manually quantified the immunohistochemical expression. The comparative data were analyzed statistically with the Kruskal–Wallis test (p < 0.05), while the correlative data were analyzed with Spearman’s rho (p<0.01). Results: 32 samples were obtained according to the inclusion criteria. The Kruskal–Wallis test showed significant differences in VEGF expression (p = 0.003) and CD34 expression (p = 0.026). The pairwise comparison test showed that VEGF expression in follicular ameloblastoma significantly differed from plexiform (p = 0.001) and combination (p = 0.002). The pairwise comparison test for CD34 expression showed a significant difference between follicular and combination ameloblastoma (p = 0.007). Spearman’s rho test showed a positive correlation (p = 0.001, r = 0.565) between markers. Conclusion: Follicular ameloblastoma expressed higher VEGF than plexiform and combination ameloblastoma. Follicular ameloblastoma expressed higher CD34 than combination types. CD34 expression is associated with VEGF in histological types of ameloblastoma.
IMPACT OF THE COVID-19 PANDEMIC ON THE DENTAL EMERGENCY DEPARTMENT SERVICE PATTERN: EXPERIENCE OF A UNIVERSITY-BASED DENTAL HOSPITAL IN INDONESIA Djimantoro, Eka Pramudita; Nafisah, Riznasyarielia Nikmatun; Kamadjaja, David Buntoro
Dentino: Jurnal Kedokteran Gigi Vol 11, No 1 (2026)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v11i1.26116

Abstract

Background: The COVID-19 pandemic and the policies taken by the Indonesian government have had a major impact on health sectors and resulted in changes in health services patterns provided by the Emergency Department (ED) in dental hospitals. Identifying changes in dental hospital visits is pivotal to formulate policies that must be prepared immediately and adapted to the dynamics for the use of dental and oral health service during pandemic. Objective: This study compares services at the ED of the Universitas Airlangga Dental Hospital during the pre-pandemic and the beginning of the COVID-19 pandemic.Method:This is a retrospective study, based on data extracted from the medical records of all patients who came to the ED during March-July 2019 and the COVID-19 period (March-July 2020). Patients were classified according to the case diagnosis, and the data of the two periods were statistically compared using the independent t-test or the Mann-Whitney U test, as applicable. Results:There was an increase in the number of patient visits in March-July 2020 (503 patients) compared to March-July 2019 (113 patients). The highest number of visits was in April 2020 (143 patients). Infection and miscellaneous cases were the most common in both periods with drastic increase in 2020. There were significant differences in the total number of visits, infections, and miscellaneous cases.Conclusion: The COVID-19 pandemic in Indonesia has caused a change in the general picture of dental and oral health services by an increase in patient number and case distribution.Keywords:COVID-19, Dental hospital, Emergency department, Health service, Pandemic