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All Journal Folia Medica Indonesiana Dental Journal (Majalah Kedokteran Gigi) Jurnal Pengabdian Masyarakat dalam Kesehatan Indian Journal of Forensic Medicine & Toxicology
Andra Rizqiawan
Faculty Of Dental Medicine, Universitas Airlangga, Surabaya
Dentistry Health Professions Nursing Public Health Other

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Identification of Single Nucleotide Polymorphism on Bone Morphogenetic Protein 2 Gene in Non-Syndromic Cleft Lip/ Palate Patient Mala Kurniati; RM Coen Pramono D; Agung Sosiawan; David Sontani Perdanakusuma; Hari Basuki Notobroto; Andra Rizqiawan
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16954

Abstract

Cleft lip/palate (CL/P) is one of the most common birth defects in humans. Haploinsufficiency in genesBone Morphogenetic Protein (BMP) 2 is thought to play an important role in the incidence of CL/P. Thisstudy aimed to identify changes in the nucleotide (Single Nucleotide Polymorphism/SNP) BMP 2 rs235768A>T gene in CL/P patient in Indonesia. Seventy samples of DNA that were successfully amplified andrestricted consisted of patient and control samples with the three of which were used for sequencing. Basedon the analysis using restriction enzymes and Finch TV and Bioedit software programs, this study identifieda change from nucleotide A to nucleotide T which is a mutation missense (Serine-Arginine/TCA-TCT).Based on the results of the Fisher’s exact test, there was difference in genotype frequency between the CL/Pgroup and the control. Meanwhile, there was no difference in allele frequencies between the two groups. Theallele frequency T has a higher value than the frequency of the allele A.
Considerations in performing odontectomy under general anesthesia: case series Anindita Zahratur Rasyida; Andra Rizqiawan
Dental Journal (Majalah Kedokteran Gigi) Vol. 51 No. 4 (2018): December 2018
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1116.574 KB) | DOI: 10.20473/j.djmkg.v51.i4.p185-188

Abstract

Background: An odontectomy constitutes a common surgical procedure performed by oral and maxillofacial surgeons on a daily basis. The anesthesia procedure required during this form of operation may involve the administering of a general anesthesia which, while a safe procedure when performed by an anesthesiologist, still involves an element of risk and should only be undertaken with appropriate safeguards. Various measures, not only anxiety control-based, are suggested in this article. Purpose: The purpose of this study was to report considerations factors, other than anxiety, as indications in performing odontectomy conducted under a general anesthesia at Universitas Airlangga Hospital, Surabaya, Indonesia. Cases: Four cases of patients who had undergone an odontectomy under a general anesthetic are reported here. Case management: The four cases of management involved odontectomies conducted under a general anesthetic for a variety of reasons with contrasting outcomes. The treatment of the four patients was based on an anatomical approach and previously ineffective pain control due to greater trauma. One of the patients also suffered from schizophrenia that produced comorbidity requiring holistic observation. This individual required intricate surgery whose performance was challenging under a local anesthetic. None of our other patients suffered from serious complications related either to surgery or the administering of a general anesthetic. Conclusion: In conclusion, important factors relating to an odontectomy performed under a general anesthetic on four patients in Universitas Airlangga Hospital, Surabaya included: anxiety, anatomical approach, adequate pain control, comorbidity of systemic medical conditions and the potential need for surgical procedures difficult to perform under a local anesthetic.
Case report: Dentigerous Cyst and Canine Impaction at the Orbital Floor Ferdian rizky Hutomo; Ellen Satya Pratiwi; Viskasari P Kalanjati; Andra Rizqiawan
Folia Medica Indonesiana Vol. 55 No. 3 (2019): September
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (220.256 KB) | DOI: 10.20473/fmi.v55i3.15508

Abstract

Dentigerous cysts are cysts of the epithelial lining of the jaws derived from the dental follicle of unerupted teeth. These cysts are often found during routine radiographic examination along with unerupted teeth. Dentigerous cysts are usually asymptomatic unless the size becomes large, thus causing swelling. This case report describes the management of dentigerous cyst in the upper left canine region with canine impaction to the orbital floor. Dentigerous cyst was treated with cyst enucleation but the impacted canine was not taken because of the magnitude of risk that can occur which was a disruption to the eye muscle. Conclusion. Treatment of dentigerous cysts can be performed by enucleation technique and management related the impacted tooth at the orbital floor needs a further evaluation consideration.
TOOTH EXTRACTION FOR HIV PATIENTS: A COMMUNITY SERVICE Sumarta, Ni Putu Mira; Rizqiawan, Andra; Anugraha, Ganendra; Barus, Liska; Dewantara, Danang; Kusumawardhini, Pralita; Musta'inah, Ita
Jurnal Pengabdian Masyarakat Dalam Kesehatan Vol. 6 No. 1 (2024): APRIL 2024
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jpmk.v6i1.50454

Abstract

Introduction: Patients with HIV often encounter significant oral health difficulties that can impact their overall well-being. Tooth extraction stands as a pivotal intervention to address these issues. A community service was conducted to give free tooth extraction to HIV patients and to educate patients on how such procedures can enhance their oral health by eliminating dental focal infections. Furthermore, it includes a survey component to assess patient satisfaction levels. Methods: A community service was conducted from June-August 2023 by Department of Oral and Maxillofacial Surgery at the Faculty of Dental Medicine, Universitas Airlangga, in collaboration with Yayasan Mahameru-Surabaya, Universitas Airlangga Dental Hospital. The objective was to provide oral health education, screening and tooth extraction to HIV patients, member of Yayasan Mahameru Surabaya. Tooth extractions was done by staffs and residents, telemedicine follow-up was conducted seven days post-extraction. A satisfaction survey utilizing semi-quantitative questionnaires was done to evaluate the patients' experiences with the service. Results: Forty-five HIV patients screened and 16 patients receiving tooth extraction.  The results of the survey showed that patients were satisfied with this community service activities. Questionaire  result: ease of  access to health provider (50%), ease in obtaining service (68%) patient safety during treatment (81,25%) and sufficient facility (75%). Conclusion: Community service in providing free tooth extraction for HIV patients is an effective method to ease patients accessing dental services and patients showed good satisfaction with dental services.
Degradation rate and weight loss analysis for freeze-dried, decellularized, and deproteinized bovine bone scaffolds Vidarta, Ramadhan Pramudya; Kamadjaja, David Buntoro; Danudiningrat, Coen Pramono; Amir, Muhammad Subhan; Rizqiawan, Andra; Yuliati , Anita; Darwis, Darmawan
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 1 (2025): March
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i1.p23-29

Abstract

Background: Mandibular defects, often caused by trauma, tumors, infections, and congenital issues, are commonly treated with bone grafts. Tissue engineering plays a crucial role in bone reconstruction, with scaffolds such as deproteinized bovine bone matrix (DBBM), freeze-dried bovine bone (FDBB), and decellularized FDBB (Dc-FDBB) being studied for their efficacy. Decellularization reduces the antigenic potential of FDBB. These scaffolds are designed to degrade within the body. Purpose: To analyze the weight loss and degradation rates of FDBB and Dc-FDBB materials, using DBBM as a control. Methods: This in vitro experimental study, conducted over 2 months, employed a cross-sectional approach to analyze the weight loss and degradation rates of FDBB, Dc-FDBB, and DBBM scaffolds in a simulated body fluid (SBF) solution. Results: Under dynamic immersion conditions, DBBM exhibited the highest daily weight loss at 0.741% and a degradation rate of 0.466 mg/cm²/day, followed by Dc-FDBB at 0.568% and 0.418 mg/cm²/day and FDBB at 0.525% and 0.385 mg/cm²/day. Under static immersion conditions, DBBM also showed the highest weight loss at 0.255%, with a degradation rate of 0.165 mg/cm²/day, followed by Dc-FDBB at 0.245% and 0.163 mg/cm²/day, and FDBB at 0.168% with a degradation rate of 0.126 mg/cm²/day. Significant differences were observed between scaffold groups (p = 0.000). Conclusion: DBBM, Dc-FDBB, and FDBB scaffolds meet the optimal requirements for tissue engineering materials based on their weight loss and degradation rates. DBBM demonstrated the highest values among the scaffolds analyzed.
Comparison outcome of open and close reduction treatments for parasymphysis mandibular fractures Fardhani, Annisa; Rizqiawan, Andra; Mulyawan, Indra; Anugraha, Ganendra
Dental Journal (Majalah Kedokteran Gigi) Vol. 56 No. 4 (2023): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i4.p268-272

Abstract

Background: Mandibular fracture is a condition of mandibular discontinuity. The treatment aims to reconstruct the appropriate anatomical position. Reduction is the process of repositioning fracture fragments to their original anatomical positions, which can be done by open and closed techniques. Open reduction is more invasive, and the possibility of nerve or blood vessel injury and infection postoperatively is greater. Closed reduction also has postoperative complications such as muscle atrophy, periodontal tissue and mucosa damage, speech disorders, and nutritional disorders. In the final determination of the treatment plan, the advantages, disadvantages, and risks of each treatment and the risk of complications should be sufficiently discussed with patients and the patient's guardians. Purpose: This case aims to compare the outcome of open reduction and internal fixation (ORIF) with closed reduction treatment in the management of mandibular parasymphysis fractures. Cases: Two case studies of mandibular parasymphysis fractures. Clinically, each patient had mandibular displacement and occlusion disturbance before treatment. Case Management: The treatment plan is considered by the patient's age and fracture type. One patient received ORIF, and the other received close reduction treatment with gradual repositioning. Malocclusion after treatment was absent in both cases. Conclusion: Open reduction is recommended for displaced parasymphysis fractures. In cases where the open reduction technique cannot be performed, the closed technique can be an alternative, especially on non-displaced or minimally displaced parasymphysis fractures.
The diagnostic challenges and two-step surgical approach to an infected dentigerous cyst resembling a unicystic ameloblastoma: A case report Suryabharata, Cokorda Gde; Rizqiawan, Andra; Mulyawan, Indra; Wati, Sisca Meida; Rahman, Mohammad Zeshaan
Dental Journal (Majalah Kedokteran Gigi) Vol. 56 No. 3 (2023): September
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i3.p202-207

Abstract

Background: A dentigerous cyst is the second-most frequently observed odontogenic cyst, and an ameloblastoma is one of the most frequently observed odontogenic tumors. Both are mostly associated with an impacted mandibular third molar and have similar characteristics. Diagnostic difficulties often result in misdiagnosis and remain a challenge to overcome. Comprehensive clinical, radiographic, and histopathological views are essential to correctly diagnose the problem and formulate the most suitable treatment plan. Purpose: This case report aims to present a thorough approach to the diagnostic and surgical procedures involved in treating a dentigerous cyst that resembles an ameloblastoma by using marsupialization followed by enucleation. Case: This article presents the case report of a 27-year-old male patient with an infected dentigerous cyst resembling a unicystic ameloblastoma associated with a totally impacted lower mandibular left third molar. The patient had a history of swelling, pain, and pus drainage in the retromolar area. Symptoms subsided after antibiotic and analgesic prescriptions, but the lesion remained and was slowly progressing. The diagnostic approach began with a fine-needle aspiration biopsy, and the result confirmed a benign cystic lesion that was suspected to be an odontogenic tumor. Then an incisional biopsy was conducted under local anesthesia, diagnosing an infected dentigerous cyst. Case Management: Marsupialization and decompression using an obturator was preferred, followed by enucleation. Nine months later, a radiographic examination revealed satisfactory bone regeneration without recurrence. Conclusion: An incisional biopsy plays a vital role in establishing a definitive diagnosis. Marsupialization followed by enucleation offers an excellent combination of treatments achieving complete cyst removal, anatomical structure preservation, and bone regeneration with minimal complications.
Co-Authors Agung Sosiawan Amir, Muhammad Subhan Barus, Liska Darmawan Darwis David B. Kamadjaja David Sontani Perdanakusuma Dewantara, Danang Ellen Satya Pratiwi Fardhani, Annisa Ferdian rizky Hutomo Ganendra Anugraha Hari Basuki Notobroto Mala Kurniati Musta'inah, Ita Ni Putu Mira Sumarta Pralita Kusumawardhini Rahman, Mohammad Zeshaan Rasyida, Anindita Zahratur RM Coen Pramono D Sisca Meida Wati Suryabharata, Cokorda Gde Vidarta, Ramadhan Pramudya Viskasari P. Kalanjati Yuliati , Anita