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All Journal International Journal of Public Health Science (IJPHS) Majalah Kedokteran Gigi Indonesia ODONTO Dental Journal Dental Journal (Majalah Kedokteran Gigi) B-Dent, Jurnal Kedokteran Gigi Universitas Baiturrahmah INDONESIAN JOURNAL OF MEDICAL ANTHROPOLOGY Odonto dental journal
Ananto Ali Alhasyimi
Department Of Orthodontics, Faculty Of Dentistry, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia
Humanities Dentistry Environmental Science Health Professions Medicine & Pharmacology Public Health Social Sciences

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Comprehensive therapies for severe facial pain related to temporomandibular disorder in a patient with mental instability Huri, Stevani Gracela; Ismiyati, Titik; Barunawati, Sri Budi; Alhasyimi, Ananto Ali; Ruspita, Intan
Majalah Kedokteran Gigi Indonesia Vol 11, No 1 (2025): April
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.104377

Abstract

The etiology of temporomandibular disorders (TMDs) is multifactorial and often associated with biopsychosocial factors. Stress, anxiety, and depression contribute to the psychological conditions that may accompany TMD. This case study aims to describe the treatment of severe facial pain associated with TMD in a patient experiencing mental instability. A 28-year-old female presented to a dental hospital with severe pain in the right facial region. The patient had previously worn a stabilizing occlusal splint six months prior, but had since lost it, resulting in the recurrence of pain. The pain originated in the right temporomandibular joint and radiated to the ear, eye, and temporal region. The pain was exacerbated by mouth opening, chewing hard food, and emotional stress. Clinical examination revealed missing lower first molars and an anterior crossbite. The patient reported frequent clenching episodes during periods of anxiety and depression. A panoramic radiograph showed both condyles to be normal in shape and size. A transcranial X-ray revealed the right condyle positioned within the glenoid fossa, while the left condyle was located anterior and inferior to the articular eminence. Treatment included a comprehensive approach: pharmacologic therapy, elimination of parafunctional habits, self-management strategies, a stabilizing splint, partial dentures, psychiatric intervention, and orthodontic treatment. The masticatory muscles showed significant relaxation following treatment, resulting in pain reduction. Orthodontic correction of the malocclusion and increased vertical dimension of occlusion led to improved quality of life and the resolution of TMJ symptoms.
Effect of carbonated hydroxyapatite synthesis from cuttlefish shells on orthodontic relapse prevention: in silico study Setyoko, Bondan; Verisandri, Aufa Lufhf Ambar; Damayanti, Adelia Tantri; Fitriana, Firda Ayu; Julieta, Berliant Salsabila; Noviasari, Paramita; Alhasyimi, Ananto Ali
Odonto : Dental Journal Vol 10, No 1 (2023): July 2023
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.10.1.19-27

Abstract

Background: Relapse occurs frequently, 70–90% of the time, and typically compromises the outcome of orthodontic therapy. Calcium carbonate (CaCO3), which is found in cuttlefish shells, can be used to make a better biomaterial. One example is carbonated hydroxyapatite, which is very similar to human bone tissue and can stop osteoclast activity on the pressure side of the retention phase. This is a factor in orthodontic relapse, which is when the bone doesn't remodel properly. In this study, a test was done to see if carbonated hydroxyapatite (CHA) could be used as an alternative material to stop orthodontic relapse. The test was based on how the RANK-RANKL, OPG, and TGF-β proteins interacted with each other. Method: CHA extracted from cuttlefish shells after 6 hours of calcination at 1000°C. RANK-RANKL, OPG, and TGF-β interactions were investigated in silico using molecular docking. Result: A cuttlefish shell extract containing CHA has the potential to be used as an alternate material to prevent orthodontic recurrence. CHA chemicals can disrupt the link between RANK and RANKL and enhance OPG and TGF-β expression. This induces enhanced proliferation, which increases the number of osteoblasts and osteoblast differentiation while decreasing the rate of osteoclast activity. Conclusion: Cuttlefish shell with CHA extract has the potential to be used as an alternative material to prevent orthodontic relapse.
Effect of carbonated hydroxyapatite synthesis from cuttlefish shells on orthodontic relapse prevention: in silico study Setyoko, Bondan; Verisandri, Aufa Lufhf Ambar; Damayanti, Adelia Tantri; Fitriana, Firda Ayu; Julieta, Berliant Salsabila; Noviasari, Paramita; Alhasyimi, Ananto Ali
Odonto : Dental Journal Vol 10, No 1 (2023): July 2023
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.10.1.19-27

Abstract

Background: Relapse occurs frequently, 70–90% of the time, and typically compromises the outcome of orthodontic therapy. Calcium carbonate (CaCO3), which is found in cuttlefish shells, can be used to make a better biomaterial. One example is carbonated hydroxyapatite, which is very similar to human bone tissue and can stop osteoclast activity on the pressure side of the retention phase. This is a factor in orthodontic relapse, which is when the bone doesn't remodel properly. In this study, a test was done to see if carbonated hydroxyapatite (CHA) could be used as an alternative material to stop orthodontic relapse. The test was based on how the RANK-RANKL, OPG, and TGF-β proteins interacted with each other. Method: CHA extracted from cuttlefish shells after 6 hours of calcination at 1000°C. RANK-RANKL, OPG, and TGF-β interactions were investigated in silico using molecular docking. Result: A cuttlefish shell extract containing CHA has the potential to be used as an alternate material to prevent orthodontic recurrence. CHA chemicals can disrupt the link between RANK and RANKL and enhance OPG and TGF-β expression. This induces enhanced proliferation, which increases the number of osteoblasts and osteoblast differentiation while decreasing the rate of osteoclast activity. Conclusion: Cuttlefish shell with CHA extract has the potential to be used as an alternative material to prevent orthodontic relapse.
Co-Authors Anne Marie Kuijpers-Jagtman Astriana Nurfitrah Ayub, Aulia Cendrawasih Andusyana Farmasyanti Christnawati Christnawati Damayanti, Adelia Tantri Endah Mardiati, Endah Ervina Sofyanti Farmasyanti, Cendrawasih Andusyana Fitria Avriliyanti Fitriana, Firda Ayu Gio, Prana Ugiana Haryono Utomo Huri, Stevani Gracela Ida Bagus Narmada Indra, Putu Intan Ruspita, Intan Julieta, Berliant Salsabila Manurung, Prans Samuel Antony Maria Purbiati Marsetyawan HNE Soesatyo Marya, Anand Niswati Fathmah Rosyida, Niswati Fathmah Noviasari, Paramita R. Darmawan Setijanto Retnaningrum, Yanuarti Retno Iswati Rosyida, Niswati Fathmah Setyoko, Bondan Siti Sunarintyas Sri Budi Barunawati Sri Suparwitri Titik Ismiyati Vázquez-Santos, Francisco José Verisandri, Aufa Lufhf Ambar