Hendry Rusdy
Faculty Of Dentistry, Universitas Sumatera Utara, Medan, Indonesia

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Association of maternal folic acid supplementation and incidence of non-syndromic cleft lip and palate Hendry Rusdy; I. Isnandar; Indra Basar Siregar; Rizkiani Cahya Putri Sinaga
Dental Journal (Majalah Kedokteran Gigi) Vol. 55 No. 2 (2022): June 2022
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v55.i2.p76-80

Abstract

Background: Cleft lip and palate as a frequent congenital defect is caused by genetic and environmental factors. Micronutrient folic acid as an environmental factor has shown a role as a cleft lip and palate protective factor in several previous studies. Purpose: The purpose of this study was to determine the distribution of adequacy of folic acid supplementation and the association between folic acid supplementation during the first trimester of pregnancy with the incidence of cleft lip and palate at Mitra Sejati Hospital, Medan, North Sumatra, Indonesia. Methods: This study used analytical research with a case-control design and questionnaire. A Chi-square test was used to observe the association between the folic acid supplement intake during the first trimester with the incidence of cleft. The p-value ≤ 0.05 was deemed to be significant. Results: The study found that 47 mothers (51.09%) had insufficient, while 45 mothers (48.91%) had adequate folic acid supplementation. This study did not show a significant association between supplement use and all cleft incidence (p>0.05), but a significant result was found between inadequate supplementation (<400µ/day) and cleft lip with or without cleft palate occurrence (p=0.043; OR 2.4[1.022-5.625]). Conclusion: The present study showed that most pregnant women did not have sufficient folic acid supplement in the first trimester. Furthermore, inadequate maternal folic acid supplementation (<400µ/day) during the first trimester of pregnancy increased the tendency for cleft lip and cleft palate (with or without cleft lip) to occur significantly.
Efektivitas getah batang betadine (Jatropha multifida L.) terhadap penyembuhan luka pasca pencabutan gigi pada tikus Sprague-DawleyEffectiveness of betadine (Jatropha multifida L.) stem sap on the wound healing after tooth extraction in Sprague-Dawley rats Hendry Rusdy; Astri Suryani Pasaribu Saruksuk; Rahmi Syaflida Dalimunte; Gostry Aldica Dohude
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 33, No 2 (2021): Agustus 2021
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v33i2.32563

Abstract

Pendahuluan: Pencabutan gigi merupakan prosedur yang sering dilakukan di kedokteran gigi. Setelah pencabutan gigi akan dihasilkan suatu perlukaan. Proses penyembuhan luka dapat dipercepat pada kondisi tertentu. Salah satu bahan alami yang dapat membantu proses penyembuhan luka adalah getah tanaman betadine (Jatropha multifida L.). Penelitian bertujuan untuk menganalisis efektivitas getah tanaman betadine terhadap penyembuhan luka dan terhadap tanda-tanda infeksi pasca pencabutan gigi Metode: Desain penelitian studi eksperimental laboratorium dengan rancangan penelitian post-test only control group design menggunakan 30 ekor tikus Sprague-Dawley. Teknik pengambilan sampel yaitu convenience sampling. Sampel dibagi menjadi 2 kelompok yaitu kelompok perlakuan dan kelompok kontrol. Kelompok perlakuan diberikan getah tanaman betadine dan kelompok kontrol diberikan asam traneksamat secara oral menggunakan sonde lambung. Tunggu selama 4 jam setelah pemberian getah tanaman betadine dan asam traneksamat. Anestesi pada tikus menggunakan ketamin 50 mg/kg berat badan secara intramuskular kemudian dilakukan pencabutan pada gigi tikus. Pengamatan dilakukan dengan melihat kriteria klinis pada hari 1,3,7 dan diperhatikan sampai luka sembuh serta lihat tanda-tanda infeksi. Analisis data dilakukan dengan uji normalitasShapiro Wilik. Hasil penelitian menunjukkan bahwa data berdistribusi tidak normal. Analisis data dilanjutkan menggunakan uji statistik mann whitney. Hasil: Terdapat perbedaan signifikan penyembuhan luka soket pasca pencabutan gigi setelah diberikan getah betadine dan asam traneksamat dengan nilai p=0,037 (p<0,005). Simpulan: Pemberian getah tanaman betadine terbukti lebih efektif terhadap proses penyembuhan luka soket pasca pencabutan gigi dibandingkan dengan pemberian asam traneksamat. Kata kunci: tikus Sprague-Dawley; penyembuhan luka; pencabutan gigi; getah batang betadine ABSTRACTIntroduction: Tooth extraction is a procedure often performed in dentistry. Tooth extraction will always cause injuries. However, the wound healing process can be accelerated under certain conditions. One of the natural ingredients that can accelerate the wound healing process is betadine (Jatropha multifida L.) plant sap. The study was aimed to analyzed the effect of betadine plant sap on wound healing and signs of infection after tooth extraction. Methods: Experimental laboratory study design with post-test only control group design was conducted towards 30 Sprague-Dawley rats. The sampling technique was convenience sampling. The sample was divided into two groups, the treatment group and the control group. The treatment group was administered with betadine plant sap, and the control group was administered with tranexamic acid orally using a gastric probe, then waited 4 hours after. The anaesthesia was then performed using 50 mg/kg body weight of ketamine intramuscularly. The extraction was performed after. Observations was conducted at the clinical criteria on days 1, 3, and 7 and continue to be monitored until the wound heals. Then, the signs of infection were observed. Data analysis was carried out using the Shapiro Wilk normality test. The results showed that the data was not normally distributed. Thus, data analysis was continued using the Mann Whitney statistical test. Results: The results showed a significant difference in the healing of socket wounds after tooth extraction after being administered with betadine sap and tranexamic acid with a value of p=0.037 (p<0.005). Conclusions: Administration of betadine plant sap is proven to be more effective in accelerating the healing process of socket wounds after tooth extraction than tranexamic acid. Keywords: Sprague-Dawley rats; wound healing; pencabutan gigi; getah batang betadine 
Cleft lip and palate based on birth order and family history at Mitra Sejati General Hospital, Indonesia Hendry Rusdy; Isnandar; Indra Basar Siregar; Veronica
Dental Journal Vol. 55 No. 4 (2022): December 2022
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v55.i4.p221-225

Abstract

Background: Cleft lip and palate is one of the most common congenital abnormalities in infants and is caused by more than one factors, which can be genetic and environmental. Defects in a family gene can result in cleft lip and palate. The study found a high family history relationship with the incidence of cleft lip and palate. Birth order studied by several researchers also has different results, which were influenced by folic acid consumption, maternal knowledge, lack of antenatal care visits and maternal age. To determine the cases of cleft lip and palate based on the birth order of the children and family history of the patients at Mitra Sejati General Hospital. Purpose: The study aimed to investigate cleft lip and cleft palate patients by birth order and family history. Methods: This research was a retrospective descriptive study using survey method. Researchers gave 13 questions through a questionnaire and data were collected and counted manually. Results: The results showed that based on the birth, the cleft case in the first birth order amounted to 25 people, the second 30 people, the third 19 people, and the fourth or more as many as 20 people. Based on family history, 27 patients had a family history of cleft lip and palate, while 67 patients did not have family history. Conclusion: The cases of clefts at Mitra Sejati General Hospital happened more frequently in the second child and most incidence did not have family history.
Perbandingan efektivitas lidokain spray 10% terhadap 15% untuk mengurangi nyeri saat pembukaan jahitan bedah minorComparison of efficacy lidocaine spray 10% and 15% for reducing pain of minor surgery suture removal Hendry Rusdy; Rezky Rahmayanti
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 34, No 3 (2022): Desember 2022
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v34i3.37282

Abstract

ABSTRAKPendahuluan: Prosedur bedah mayor maupun minor membutuhkan penjahitan pasca bedah. Saat pembukaan jahitan, pasien dapat merasakan respon nyeri karena rangsangan mekanis oleh gesekan benang. Seharusnya pasien dapat merasa nyaman saat pembukaan jahitan, Rasa nyaman pada pasien dapat diperoleh dengan menggunakan anastesi topikal sebelum pembukaan jahitan dilakukan. Tujuan: Menganalisis efektivitas lidokain spray 10% dan lidokain spray 15% dalam mengurangi rasa nyeri saat pembukaan jahitan bedah minor. Metode: Jenis penelitian eksperimental dengan menggunakan posttest only control group design. Teknik pengambilan sampel purposive sampling dan diperoleh sampel penelitian sebanyak 30 orang. Kriteria Inklusi penelitian pasien yang akan menjalani prosedur pembukaan jahitan bedah minor di RSGM-P USU, tidak ada tanda infeksi pada jahitan, jenis jahitan interrupted suture. Kriteria eksklusi pasien yang tidak bersedia ikut serta dalam penelitian. Sampel dibagi menjadi 3 kelompok, setiap kelompok terdiri dari 10 pasien yang diberikan lidokain spray 10% (X1), lidokain spray 15%(X2) dan kelompok yang tidak diberi anastesi topikal (kelompok kontrol). Rasa sakit setelah tindakan dilakukan pengukuran dengan instrument Visual Analogue Scale (VAS). Hasil dianalisis menggunakan uji Mann-Whitney. Hasil: Hasil uji statistik menunjukkan kelompok lidokain spray 10% dan lidokain spray 15% (p=0,675) tidak terdapat perbedaan efektivitas yang signifikan. Terdapat perbedaan efektivitas yang signifikan pada kelompok lidokain spray 10% dan Kontrol (p=0,001). Terdapat perbedaan efektivitas yang signifikan antara kelompok lidokain spray 15% dan Kontrol (p=0,003). Simpulan: Lidokain spray 10% memiliki efektivitas yang sama dengan lidokain spray 15% dalam mengurangi rasa nyeri saat pembukaan jahitan bedah minor, namun lidokain spray 15% memiliki masa kerja yang lebih panjang (15-20 menit) dibandingkan lidokain spray 10% (10-15 Menit). Kata kunci: pembukaan jahitan; nyeri; lidokain spray 10%; lidokain spray 15%ABSTRACTIntroduction: Mayor and minor surgical procedures often require postoperative suturing. During the suture removal process, patients can feel pain due to mechanical stimulation of friction of the thread. Comfort feeling during suture removal is performed by using a topical anesthetic agent before suture removal procedure. The purpose is to analyze the efficacy of 10% and 15% lidocaine spray in reducing pain during suture removal of minor oral surgery. Methods: This study was with three group post-test only control group design. Sampling Technique was purposive sampling, and the sample obtained was 30 people. The inclusion criteria were patients undergoing minor surgical suture removal procedures at RSGMP USU, no signs of infection in the sutures, and the suture type was interrupted. The exclusion criteria were patients who were not wanted to participate in the study. The sample was divided into three groups. Each group consisted of 10 patients receiving 10% (X1) and 15% (X2) lidocaine spray, and the group was not given topical anesthetic agents. Postoperative pain was assessed using a visual analog scale. The result was statistically analyzed using Mann Whitney test. Results: The result showed that the lidocaine spray 10% and lidocaine spray 15% were not statistically different (p=0,675). There was a significant difference between lidocaine spray 10% and control group (p=0,001), and there was a significant difference between lidocaine spray 15% and control group (p=0,003). Conclusion: Lidocaine spray 10% has the same efficacy as lidocaine spray 15% in reducing pain during suture removal of minor oral surgery. However, lidocaine spray 15% (15-20 minutes) has a longer duration of action than lidocaine spray 10% (10-15 minutes).Keywords: suture removal; pain; lidocaine spray 10%; Lidocaine spray 15%