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All Journal Dental Journal (Majalah Kedokteran Gigi) Jurnal Kedokteran Gigi Universitas Padjadjaran Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat Eureka Herba Indonesia Jurnal of Syiah Kuala Dentistry Society
Dohude, Gostry Aldica
Department Of Oral And Maxillofacial Surgery, Faculty Of Dentistry, Universitas Sumatera Utara, Medan, Indonesia
Agriculture, Biological Sciences & Forestry Dentistry Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Social Sciences

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Efektivitas getah batang betadine (Jatropha multifida L.) terhadap penyembuhan luka pasca pencabutan gigi pada tikus Sprague-DawleyEffectiveness of betadine (Jatropha multifida L.) stem sap on the wound healing after tooth extraction in Sprague-Dawley rats Hendry Rusdy; Astri Suryani Pasaribu Saruksuk; Rahmi Syaflida Dalimunte; Gostry Aldica Dohude
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 33, No 2 (2021): Agustus 2021
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v33i2.32563

Abstract

Pendahuluan: Pencabutan gigi merupakan prosedur yang sering dilakukan di kedokteran gigi. Setelah pencabutan gigi akan dihasilkan suatu perlukaan. Proses penyembuhan luka dapat dipercepat pada kondisi tertentu. Salah satu bahan alami yang dapat membantu proses penyembuhan luka adalah getah tanaman betadine (Jatropha multifida L.). Penelitian bertujuan untuk menganalisis efektivitas getah tanaman betadine terhadap penyembuhan luka dan terhadap tanda-tanda infeksi pasca pencabutan gigi Metode: Desain penelitian studi eksperimental laboratorium dengan rancangan penelitian post-test only control group design menggunakan 30 ekor tikus Sprague-Dawley. Teknik pengambilan sampel yaitu convenience sampling. Sampel dibagi menjadi 2 kelompok yaitu kelompok perlakuan dan kelompok kontrol. Kelompok perlakuan diberikan getah tanaman betadine dan kelompok kontrol diberikan asam traneksamat secara oral menggunakan sonde lambung. Tunggu selama 4 jam setelah pemberian getah tanaman betadine dan asam traneksamat. Anestesi pada tikus menggunakan ketamin 50 mg/kg berat badan secara intramuskular kemudian dilakukan pencabutan pada gigi tikus. Pengamatan dilakukan dengan melihat kriteria klinis pada hari 1,3,7 dan diperhatikan sampai luka sembuh serta lihat tanda-tanda infeksi. Analisis data dilakukan dengan uji normalitasShapiro Wilik. Hasil penelitian menunjukkan bahwa data berdistribusi tidak normal. Analisis data dilanjutkan menggunakan uji statistik mann whitney. Hasil: Terdapat perbedaan signifikan penyembuhan luka soket pasca pencabutan gigi setelah diberikan getah betadine dan asam traneksamat dengan nilai p=0,037 (p<0,005). Simpulan: Pemberian getah tanaman betadine terbukti lebih efektif terhadap proses penyembuhan luka soket pasca pencabutan gigi dibandingkan dengan pemberian asam traneksamat. Kata kunci: tikus Sprague-Dawley; penyembuhan luka; pencabutan gigi; getah batang betadine ABSTRACTIntroduction: Tooth extraction is a procedure often performed in dentistry. Tooth extraction will always cause injuries. However, the wound healing process can be accelerated under certain conditions. One of the natural ingredients that can accelerate the wound healing process is betadine (Jatropha multifida L.) plant sap. The study was aimed to analyzed the effect of betadine plant sap on wound healing and signs of infection after tooth extraction. Methods: Experimental laboratory study design with post-test only control group design was conducted towards 30 Sprague-Dawley rats. The sampling technique was convenience sampling. The sample was divided into two groups, the treatment group and the control group. The treatment group was administered with betadine plant sap, and the control group was administered with tranexamic acid orally using a gastric probe, then waited 4 hours after. The anaesthesia was then performed using 50 mg/kg body weight of ketamine intramuscularly. The extraction was performed after. Observations was conducted at the clinical criteria on days 1, 3, and 7 and continue to be monitored until the wound heals. Then, the signs of infection were observed. Data analysis was carried out using the Shapiro Wilk normality test. The results showed that the data was not normally distributed. Thus, data analysis was continued using the Mann Whitney statistical test. Results: The results showed a significant difference in the healing of socket wounds after tooth extraction after being administered with betadine sap and tranexamic acid with a value of p=0.037 (p<0.005). Conclusions: Administration of betadine plant sap is proven to be more effective in accelerating the healing process of socket wounds after tooth extraction than tranexamic acid. Keywords: Sprague-Dawley rats; wound healing; pencabutan gigi; getah batang betadine 
Tingkat pengetahuan mahasiswa kedokteran gigi tentang faktor risiko karsinoma sel skuamosa rongga mulutKnowledge level of oral squamous cell carcinoma risk factors Among dental students Gostry Aldica Dohude; Cindy Audria
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 34, No 2 (2022): Agustus 2022
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v34i2.34845

Abstract

ABSTRAKPendahuluan: Karsinoma sel skuamosa rongga mulut (KSS) merupakan salah satu jenis tumor ganas yang berasal dari displasia jaringan lunak epitelium, hal ini ditandai dengan perubahan proliferasi sel skuamosa displastik pada permukaan lapisan epitelium yang ada di rongga mulut. Insidensi kanker mulut yang masih terus meningkat diakibatkan karena adanya perbedaan faktor risiko di berbagai negara terutama Asia. Selain faktor dari dalam (endogen) seperti genetik dan malnutrisi, faktor risiko KSS dapat berasal dari lingkungan (eksogen) yaitu paparan sinar matahari secara kronis, Human papillomavirus dan kebiasaan buruk (merokok, menyirih, mengonsumsi alkohol serta makanan dan minuman yang panas secara berlebihan). Tujuan penelitian untuk mengetahui tingkat pengetahuan mahasiswa program profesi tentang faktor risiko karsinoma sel skuamosa rongga mulut. Metode Jenis penelitian survei deskriptif dengan desain cross sectional. Penelitian dilakukan dengan menggunakan kuesioner online yang diberikan kepada 106 mahasiswa Program Profesi Kedokteran Gigi. Responden dipilih dengan menggunakan teknik simple random sampling. Hasil ukur pengetahuan responden dikategorikan menjadi baik jika skor yang didapat >75%, cukup jika skor yang didapat 56-75% dan kurang jika skor yang didapat <56% dari seluruh pertanyaan. Hasil: Terdapat 47 responden (44,3%) memiliki tingkat pengetahuan baik, 42 responden (39,6%) yang memiliki pengetahuan cukup dan 17 responden (16%) yang memiliki tingkat pengetahuan kurang. Simpulan: Pengetahuan mahasiswa program profesi tentang faktor risiko KSS sudah termasuk dalam kategori baik, meskipun terdapat beberapa responden yang memiliki pengetahuan cukup hingga kurang.Kata kunci: pengetahuan; faktor risiko; karsinoma sel skuamosa; mahasiswa kedokteran gigi ABSTRACTIntroduction: Oral squamous cell carcinoma (OSCC) is a type of malignant epithelial neoplasm originating from epithelial soft tissue dysplasia, it is characterized by proliferation changes of dysplastic squamous cells on epithelium layer surface in oral cavity. In addition to internal factors such as genetics and malnutrition, risk factors of OSCC can come from the environment namely chronic sun exposure, human papillomavirus and lifestyle (smoking, betel chewing, drinking alcohol and consuming hot food and drinks). Methods: This study was a descriptive study with cross sectional design and was conducted using an online questionnaire that was given to 106 clinical dental students. Respondents were selected using simple random sampling technique. Respondents knowledge measurement results were categorized as good if the obtained score was >75%, sufficient if the obtained score was 56-75 and low if the obtained score was <56 of all questions. Results: Based on the distribution of respondents knowledge level about OSCC, 47 respondents (44.3%) had good knowledge level of OSCC, 39.6% of respondents had sufficient knowledge and 16% of respondents had low knowledge level. Conclusion: Clinical dental students knowledge about OSCC is in good category, although there were some respondents who have sufficient to less knowledge.Keywords: knowledge; risk factors; oral squamous cell carcinoma; dental students
The Effectiveness of Using Jengkol Peel Extract (Pithecellobium lobatum Benth.) in Inhibits Bacterial Growth Staphylococcus aureus In Vitro Indra Basar Siregar; Gostry Aldica Dohude; Rahmi Syaflida Dalimunte; Zata Amani, A Rachma
Eureka Herba Indonesia Vol. 4 No. 3 (2023): Eureka Herba Indonesia
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ehi.v4i3.87

Abstract

Staphylococcus aureus is aerobic bacteria that are gram-positive and are one of the normal human flora on the skin and mucous membranes. Most infections in the oral cavity are caused by Staphylococcus aureus, which is a normal flora in the oral cavity that can turn into a pathogen if trauma or abrasion occurs on the mucosal surface. Jengkol peel is thought to contain tannin compounds, which have the potential as an anti-inflammatory, anti-diarrheal, antioxidant, treatment of infections of the skin and mouth, and treatment of burns. This study aimed to explore the potential of jengkol peel extract (Pithecellobium lobatum Benth.) as an antibacterial Staphylococcus aureus regularly in vitro. This study is an experimental research in vitro, where as many as 7 treatment groups were used in this study. Positive and negative controls and extract concentrations of 5%-80% were used as the treatment group. Analysis of the average diameter of the inhibition of bacterial growth was carried out using SPSS version 25 software. The potential inhibition of jengkol peel extract was in line with the increase in the concentration of jengkol peel extract. The higher the concentration of jengkol peel extract, the greater the inhibition of bacterial growth. Extract concentration of 20% has a comparable inhibition of bacterial growth control positive. Jengkol peel extract effectively inhibits the growth of Staphylococcus aureus bacteria. Jengkol peel extract concentration of 20% has effectiveness in inhibiting bacterial growth equivalent to 0.2% chlorhexidine in vitro.
Long-standing pleomorphic adenoma in hard palate: A rare case report Hanafiah, Olivia Avriyanti; Dohude, Gostry Aldica; Ayuni HG, Afifah; Tanandika, Janesia; Wirsa, Dinda Andaru
Dental Journal (Majalah Kedokteran Gigi) Vol. 57 No. 4 (2024): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v57.i4.p305-309

Abstract

Background: Pleomorphic adenoma (PA) is the most common benign tumor of the parotid gland, followed by the submandibular gland, and rarely in the minor salivary glands. However, it has the potential to turn malignant. The minor salivary gland in the hard palate is a rare site for PA. Purpose: This report aims to describe the clinical and histopathology findings and treatment with surgical excision of long-standing PA on the hard palate. Case: 40-year-old woman with an asymptomatic 6 x 4 x 4 cm hard palate tumor mass that had remained untreated for ten years and had no preceding trauma. Case Management: The tumor mass was removed surgically by creating an excision opening of 2–3 mm between the mass margin and the maxillary bone periosteum, extending to the posterior palate. Histopathology findings confirmed the diagnosis of PA in the minor salivary gland and revealed typical characteristics associated with malignant transformation.  Observation after one month showed that the surgical wound had healed, and no symptoms of recurrence were visible. Conclusion: PA is a benign salivary gland tumor that has the potential to expand extensively. Appropriate surgical excision can improve the prognosis.
Inhibitory test of turmeric leaves extract (Curcuma Longa. L) against the growth of Streptococcus mutans bacterial growth in vitro Gostry Aldica DOHUDE; Hendry RUSDY; Olivia Avriyanti HANAFIAH; Preetypal Kaur JOHAL
Journal of Syiah Kuala Dentistry Society Vol 7, No 2 (2022): December 2022
Publisher : Dentistry Faculty

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jds.v7i2.30229

Abstract

Streptococcus mutans is a bacterium that plays an essential role in forming dental caries. Odontogenic infection is an oral cavity infection that can develop from dental caries if not appropriately treated. Caries treatment can be done with the use of antimicrobial agents. The increasing resistance to antimicrobial drugs has made herbal medicines the choice because they are more effective and less harmful. The community uses turmeric leaves as a cooking spice and treatment for stomach aches in children. Turmeric leaf extract contains flavonoids, tannin, and phenolic antimicrobial active compounds. This research aims to find out if turmeric leaf extract inhibits the growth of the Streptococcus mutans. This study uses a post-test-only control condition approach in a laboratory setting. The concentration of turmeric leaf extract tested was 10%, 15%, and 20% with the positive control (Chlorhexidine 0,2% mouthwash) and negative control (DMSO) with five repetitions. Antibacterial effectiveness test using Kirby-Bauer disc diffusion method. The data analysis using ANOVA showed a p-value of 0.00 on inhibition, which indicates that turmeric leaf extract can suppress the development of Streptococcus mutans. The average inhibition zone obtained was 8.7 mm at a concentration of 10%, at a concentration of 15% at 9.5 mm, and at a concentration of 20% at 8.54 mm. This research concludes that turmeric leaf extract can inhibit the proliferation of Streptococcus mutans bacteria KEYWORDS: Turmeric Leaf, Streptococcus mutans, Antibacterial
Teacher Training On The Maintenance Of Oral Hygiene And Dental Trauma In Children To Improve Oral Health In Madrasah / Ra Mtsi PTPN IV Kebun Balimbingan Matondang, Siska Ella Natassa; Dohude, Gostry Aldica; Ranu Putra Armidin
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 5 No. 2 (2020): ABDIMAS TALENTA : Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (667.514 KB) | DOI: 10.32734/abdimastalenta.v5i2.4988

Abstract

Dental caries is a disease that is mostly found in the oral cavity together with periodontal disease, so it is a major problem of dental and oral health. Based on the results of basic health research (RISKESDAS) in 2007 in 28 Indonesian provinces, it was found that the prevalence of caries in Indonesia was 67.4%, while the prevalence of active caries (untreated caries) was 43.4%. Many children have cavities and residual roots. Children are not able to independently maintain the health of their teeth and mouth. Apart from parents, school teachers have a big role in improving children's oral and dental health. The role of the teacher is meaningful in this case, because the teacher will meet almost every day with the child. However, the reality is that school teachers do not have skills in maintaining oral health, and the level of knowledge about oral health is still low. Therefore, community service for children is needed in the form of dental health education and joint tooth brushes. Besides that, skills training on brushing teeth also needs to be carried out for teachers. The aim of this service is to improve children's dental health by providing dental health education, joint brushing and increasing teacher knowledge and skills in helping to brush teeth in school children. The method of implementing community service is in the form of dental health education for children, and conducting training for school teachers on oral and dental health. It is hoped that with the dedication carried out, there will be an increase in dental and oral health in children and an increase in knowledge and skills of school teachers.
Antibacterial Activity of Zanthoxylum acanthopodium DC. Against Streptococcus viridans: An Evaluation of Growth Inhibition Potential Dohude, Gostry Aldica; Ridho, Muhammad Fathur; Hanafiah, Olivia Avriyanti; Rusdy, Hendry
Journal of Syiah Kuala Dentistry Society Vol 9, No 2 (2024): December 2024
Publisher : Dentistry Faculty

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jds.v9i2.40316

Abstract

Background: The oral cavity serves as the primary entry point for food and harbors various microorganisms, some of which can cause post-tooth extraction infections, such as dry sockets. One of the bacterial species responsible for this condition is S. viridans. Infection prevention is commonly achieved through the administration of antibiotics; however, excessive use of antibiotics can contribute to bacterial resistance. As a result, there is growing interest in exploring natural alternatives for infection control. One potential natural antibacterial agent is Andaliman fruit (Zanthoxylum acanthopodium DC.), which is traditionally recognized for its medicinal properties. Objective: This study aims to evaluate the antibacterial activity of Andaliman fruit extract (Zanthoxylum acanthopodium DC.) against S. viridans in vitro. Methods: This study employed a laboratory experimental approach using Andaliman fruit extract at various concentrations (50%, 25%, 12.5%, 6.25%, and 3.125%). Chlorhexidine digluconate 0.2% was used as a positive control, while Dimethyl sulfoxide (DMSO) was a negative control. The antibacterial activity was assessed by applying these concentrations to paper discs and measuring the inhibition zones formed. Results: Statistical analysis using the Kruskal-Wallis test showed a significant antibacterial effect of Andaliman fruit extract with a p-value of 0.000, indicating a concentration-dependent response in inhibiting S. viridans growth. Conclusion: Andaliman fruit extract exhibits antibacterial activity against S. viridans, with the most effective concentration being 50%. However, its inhibitory effect remains lower than that of the positive control (Chlorhexidine digluconate 0.2%), suggesting that further research is needed to enhance its antibacterial potency.
Effectivity of Mengkudu (Morinda citrifolia) Fruit Extract in Inhibiting the Growth of Streptococcus viridans Causing Dry Socket Post Extraction Dohude, Gostry Aldica; -, Ahyar Riza; Siregar, Indra Basar; -, Ayu Lestari
Journal of Syiah Kuala Dentistry Society Vol 9, No 1 (2024): June 2024
Publisher : Dentistry Faculty

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jds.v9i1.37845

Abstract

Background: Post-extraction wound healing usually proceeds but sometimes has problems and causes complications in the form of a dry socket. Streptococcus viridans bacterial infection is one of the causes of dry socket, therefore prevention of infection can be done by providing antibiotic or antibacterial (antiseptic) therapy. Noni fruit (Morinda citrifolia) contains many phenols, saponins, and alkaloids that can potentially be antibacterials. Objective: This study aims to determine the effectiveness of noni (Morinda citrifolia) extract against Streptococcus viridans bacteria in post-extraction sockets. Methods: This type of research is a laboratory experiment with Post test only control group design, where this study uses the Kirby-Bauer diffusion method with Streptococcus viridans bacteria samples and uses noni fruit extract (Morinda citrifolia) with concentrations of 3.125%, 6.25%, 12.5%, 25%, and 50%; Positive control Chlorhexidine digluconate 0.2%; And negative control DMSO. Results: The data analysis using Kruskal-Wallis showed a p-value of 0.000 on inhibition, which showed that noni fruit extract could inhibit the growth of Streptococcus viridans bacteria. Conclusion: Noni fruit extract (Morinda citrifolia) effectively inhibits the growth of Streptococcus viridans bacteria with an effective dose of 50%, but the antibacterial activity is still below the activity of Chlorhexidine gluconate 0.2%.
Influence of Theobroma cacao L on the adhesion of Streptococcus mutans Syaflida, Rahmi; Dohude, Gostry Aldica; Isnandar, Isnandar; Sepriyani, Risa
Journal of Syiah Kuala Dentistry Society Vol 8, No 2 (2023): December 2023
Publisher : Dentistry Faculty

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jds.v8i2.29878

Abstract

Background: Indonesia is a tropical country with various plants ranging from forest products to agriculture and plantations. One of the plants with a lot of beneficial potential as a traditional medicine is the cacao plant (Theobroma cacao L.). Cocoa beans have a high content of polyphenol compounds, which significantly contribute as antioxidants, anti-cancer, anti-diabetes, anti-hypertension, and anti-inflammation. Ketekin, flavonoids, and tannins are compounds in cocoa beans known to have antimicrobial properties. Objective: This study aimed to determine the effectiveness of the antimicrobial power of cocoa bean extract in inhibiting the growth of Streptococcus mutans bacteria. Methods: This research is an experimental laboratory research. The study began with the manufacture of cocoa bean extract made into five concentrations, namely 50%, 25%, 12.5%, 6.25%, and 3.125%. This research was conducted by measuring the diameter of the inhibition zone through the Kirby-Bauer disk diffusion method using chlorhexidine 0.2% positive control and DMSO negative control. Results: The results showed at the largest concentration of 50%, the average value of the inhibitory zone obtained was 19.10 0.25 mm, and the smallest concentration of 3.12% was 7.25 0.29 mm. Conclusion: The study concludes that Cocoa bean extract effectively inhibits the growth of Streptococcus mutans.
Antimicrobial Assessment of Curcuma longa L Against Streptococcus mutans Growth Dohude, Gostry Aldica; Isnandar, Isnandar; Siregar, Indra Basar; Tanzia, Allisha
Journal of Syiah Kuala Dentistry Society Vol 8, No 1 (2023): June 2023
Publisher : Dentistry Faculty

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jds.v8i1.33031

Abstract

Background. Streptococcus mutans is the most common oral endogenous microorganism found at the beginning of plaque formation until the formation of dental caries. If not handled properly, caries can lead to odontogenic infections. Increased resistance to antimicrobial drugs has made herbal ingredients an alternative treatment because they are more effective and do not cause side effects. This turmeric leaf contains active antimicrobial compounds of flavonoids, tannins, and phenolics. Objective. This study aimed to determine the effectiveness of turmeric leaf extract (Curcuma longa. L) as an antimicrobial on the growth of Streptococcus mutans bacteria. Materials and Methods. This study uses a post-test-only control condition approach in a laboratory setting. The concentration of turmeric leaf extract tested was 10%, 15%, and 20% with the positive control (Chlorhexidine 0,2% mouthwash) and negative control (DMSO) with five repetitions. Antibacterial effectiveness test using serial dilution method. Results. The data analysis using the Oneway ANOVA test showed a p-value 0.05, meaning that the number of Streptococcus mutans bacterial colonies in both the treatment and control groups had a significant difference in number. The antibacterial effect at a 10% concentration of turmeric leaf extract (Curcuma longa. L) with an average and standard deviation of 45.20 3.83, at a 15% concentration of 43.80 3.11, at a 20% concentration of 23.60 12.30. Conclusion. This study concludes that turmeric leaf extract (Curcuma longa. L) has antibacterial effectiveness against Streptococcus mutans bacteria.Keywords: Curcuma longa L, Turmeric Leaf, Streptococcus mutans, Antibacterial
Co-Authors -, Ahyar Riza -, Ayu Lestari Allisha Tanzia Astri Suryani Pasaribu Saruksuk Ayuni HG, Afifah Br Ginting, Rachel Adinda Yule Cindy Audria Denny Satria, Denny Diana Sofia Hanafiah Harahap, Nurul Izzatunna Jhirah Hendry Rusdy Hendry Rusdy Hendry Rusdy Indra Basar Siregar Indra Basar Siregar Isnandar Isnandar Matondang, Siska Ella Natassa Olivia Avriyanti Hanafiah Olivia Avriyanti Hanafiah Preetypal Kaur JOHAL Putri, Maharani Syahnia Rachel Adinda Yule Br Ginting Rahmi Syaflida Dalimunte Ranu Putra Armidin Ridho, Muhammad Fathur Rusdy, Hendry Sepriyani, Risa Siregar, Indra Basar Syaflida, Rahmi Tanandika, Janesia Tanzia, Allisha Wirsa, Dinda Andaru Zata Amani, A Rachma