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All Journal Jurnal Online Mahasiswa (JOM) Bidang Perikanan dan Ilmu Kelautan Paediatrica Indonesiana
Dina Medina
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Earth & Planetary Sciences Health Professions Medicine & Pharmacology

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Reproductive Biology of Osteochilus hasselti C.Vfrom the Bunter Lake,Pangkalan Baru Village, Siak Hulu Sub District, Kampar Regency Riau Province Dina Medina; Deni Efizon; Efawani Efawani
Jurnal Online Mahasiswa (JOM) Bidang Perikanan dan Ilmu Kelautan Vol 7, No 1 (2020): Edisi 1 Januari - Juni 2020
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Perikanan dan Ilmu Kelautan

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Abstract Paweh fish (Osteochilus hasselti C.V) is type of fish commonly inhabit the Bunter lake of Pangkalan Baru Village. However, information on reproductive biology of the fish is rare. To understand the biological aspects of this fish, a study was conducted.The fish was sampled once at two weeks for three months period, from August to October 2019. Parameters measured were sex ratio, gonad maturity level, Gonad Somatic Index (GSI), fecundity and egg diameter. Result shown that there was 52 males and 36 females (sex ratio 1.6: 1).In each sampling time there were male and female fishes in 1st, 2nd, 3rd and 4th maturity level. The Gonad Somatic Index (GSI) of male is around 3.30%-9.64% and female is around 6.04%-16.40%. The average fecundity of the female was 10.497-29.540 eggs. Egg diameter was around 0.5-1 mm. This result indicated that paweh fish were total spawner. Keywords: Sex ratio, gonad maturity level, gonad somatic index, fecundity, total spawner
The use of 4.5% hypertonic saline challenge test in diagnosing asthma in children with chronic recurrent cough Bambang Supriyatno; Dina Medina; Alan R Tumbelaka; Nastiti N Rahajoe
Paediatrica Indonesiana Vol 45 No 3 (2005): May 2005
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi45.3.2005.93-8

Abstract

Background The 4.5% hypertonic saline (HS) challenge test hasseveral benefits compared to histamine challenge test as gold stan-dard. Saline is an inexpensive non-pharmacological substancewhich is relatively safe. Its mechanism in inducing bronchospasmresembles that of asthma. Moreover, it can easily be made in amodest medical laboratory.Objective To determine the ability of 4.5% HS challenge test com-pared to histamine challenge test in diagnosing asthma in childrenwith chronic recurrent cough (CRC).Methods This study was a diagnostic test on children with CRCaged 6 to 14 years, conducted in outpatient clinic of Department ofChild Health, Cipto Mangunkusumo Hospital, Jakarta. All subjectsunderwent lung function tests. Subjects whose FEV 1 was <80% werediagnosed as asthmatic and underwent the 4.5% HS challenge testonly. Those whose FEV 1 was 80% underwent the histamine chal-lenge test followed by the 4.5% HS challenge test one or two weekslater. Test results were expressed as positive or negative. Based onthe results, we calculated the sensitivity, specificity, predictive val-ues, and likelihood ratios of the 4.5% HS challenge test.Results Forty-five subjects, consisting of 22 boys and 23 girls,were enrolled. The average age of subjects was 9 years old. Atopichistory in the family or in subjects themselves was found in 80% ofsubjects. Eight subjects had FEV 1 of <80%. Forty-four subjectswere diagnosed with asthma based on a baseline FEV 1 of <80%or a positive histamine provocation test. Thirty-seven subjects hada positive 4.5% HS challenge test; all had asthma. Sensitivity andspecificity of the 4.5% HS challenge test were 84.1% and 100.0%,respectively; the positive and negative predictive values were100.0% and 12.5%, respectively. The positive likelihood ratio wasinfinite and negative likelihood ratio was 0.16.Conclusion The 4.5% hypertonic saline challenge test can be usedas an alternative bronchial provocation test in diagnosing asthma inchildren with CRC. Further study with larger sample size is neededfor widespread usage.
Co-Authors Alan R Tumbelaka Bambang Supriyatno Deni Efizon Efawani Efawani Nastiti N Rahajoe