Article Per Year (5 Year)
p-Index From 2021 - 2026
0.659
P-Index
This Author published in this journals
All Journal Althea Medical Journal Majalah Obstetri dan Ginekologi The Indonesian Biomedical Journal JNKI (Jurnal Ners dan Kebidanan Indonesia) (Indonesian Journal of Nursing and Midwifery)
Lilis Lilis
Atma Jaya Catholic University Of Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health Other

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
The Association of Parametrial Invasion with the Expression of Vascular Endothelial Growth Factor-C and Other Factors in Squamous Cell Cervical Carcinoma Stage IB and IIA Lilis Lilis; Nurjati Chairani Siregar; Andrijono Andrijono
The Indonesian Biomedical Journal Vol 11, No 3 (2019)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v11i3.838

Abstract

BACKGROUND: The presence of parametrial invasion in early stage squamous cell cervical cancer (SCCC) indeed indicates worse prognosis and need more adjuvant treatment. This study aimed to investigate the association between parametrial invasion and clinicohystopathology variables.METHODS: This retrospective study used specimens of squamous cell carcinoma stage IB-IIA. The inclusion criteria were cervical cancer stage IB-IIA and post radical hysterectomy with lymph node dissection and exclusion criteria was damaged and or insufficient histological preparations. The clinicohystopathology variables included age, tumour size and stage, differentiation and inflammation grade, lymphatic vascular and parametrial invasion, and lymph node metastasis. Histopathology staining, immunohistochemistry examination, and vascular endothelial growth factor-C (VEGF-C) expression were evaluated according to the standard procedure. The independent-T, Chi square, and Fisher’s exact test were applied to evaluate the association. The significance was set at p<0.05.RESULTS: Seventy-five cases were eligible. Parametrial invasion was found in 15 cases (20%). Three variables demonstrated a significant association with parametrial invasion, tumor size >4 cm (OR 4.32, 95% CI 1.29-14.38, p=0.01), lymphatic node metastasis (OR 3.90, 95% CI 1.17-13.03, p=0.02), and VEGF-C (OR 0.75, 95% CI 0.65- 0.87, p=0.03).CONCLUSION: Tumor size of >4 cm and lymph node metastasis (LNM) had a higher risk of parametrial invasion in SCCC stage IB-IIA.KEYWORDS: cervical carcinoma, parametrial invasion, vascular invasion, peritumoral stroma, VEGF-C expression
The effect of Hatha Yoga on pain intensity in severe primary dysmenorrhea among students: A randomized controlled trials Ignatio Rika Haryono; Jessica Putri Sudarman; Nawanto Agung Prastowo; Lilis Lilis
JNKI (Jurnal Ners dan Kebidanan Indonesia) (Indonesian Journal of Nursing and Midwifery) Vol 11, No 1 (2023)
Publisher : Alma Ata University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21927/jnki.2023.11(1).95-105

Abstract

Background: Yoga has been known as an alternative therapeutic modality for reducing pain. The benefits of yoga for reducing pain have been proven. Women often suffer pain due to dysmenorrhea. The effect of Yoga on dysmenorrhea pain has not been widely studiedObjectives: This study aimed to investigate the effect of hatha yoga on pain in primary dysmenorrhea (PD). Methods: This was a randomized controlled study (RCT) involving 50 female students, 25 each in control (C) and yoga group (Y). PD was diagnosed by Working ability, Location, Intensity (Wong-Baker scale), and Days of the Pain of Dysmenorrhea (WaLIDD) questionnaire. Pain intensity was assessed by the Numeric Rating Scale (NRS). Hatha yoga training was conducted for 12 weeks. The unpaired t-test, ANOVA and Tukey post hoc, and Pearson correlation test was applied. Significance was set at p<0.05. Results: The characteristics between groups were not different. ANOVA indicated the NRS score in control was not changed, while yoga was diminished (p=0.02). Tukey post hoc showed that the second and third NRS were lower than basal NRS (p=0.038 and 0.01, respectively). The third was also lower than the second NRS (p=0.039). The second and the third NRS in yoga were lower than in control (p=0.027 and <0.01, respectively). The second magnitude of change of NRS was significantly different from the first in yoga (1.92 ±2.4 vs. 3.09 ± 2.8, p=0.018). The magnitude of NRS changes in the first (0.06±1.1 vs. 1.92±2.4, p=0.013) and second (0.02 ± 1.6 vs. 3.09 ± 2.8, p= 0.004) in yoga was significantly greater than the control. NRS score was not correlated with age, BMI, and age of menarche. Conclusions: Hatha yoga exercise ameliorate pain intensity in primary dysmenorrhea among female university students.
Association Between High-Sodium Food Consumption and Sleep Quality among Young Adults Anthony Andrew Gunarso; Lilis Lilis; Vetinly Vetinly; Nanny Djaya; Poppy Kristina Sasmita
Althea Medical Journal Vol 13, No 2 (2026)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v13n2.4257

Abstract

Background: Excessive sodium intake is associated with various health issues, including hypertension and cardiovascular disorders, which may contribute to circadian rhythm disturbances and nocturnal urination that can impair sleep quality. This study aimed to explore the association between high-sodium food consumption and sleep quality among young adults.Methods: This cross-sectional study involved 107 preclinical medical students aged 18-22 years at Atma Jaya Catholic University of Indonesia, North Jakarta, Indonesia, conducted between August and October 2024. Sodium consumption data were collected using a Semi-Quantitative Food Frequency Questionnaire (SQ-FFQ), whereas sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). Participants were selected using proportional-to-size sampling. Data were analyzed using the Fisher’s Exact test.Results: Of the 107 respondents, 36.4% consumed high-sodium foods exceeding the recommended intake limits. Male respondents showed a higher mean sodium intake (2.262 mg +/- s.d) compared with female respondents (1.897 mg +/- s.d), although the difference was not statistically significant (p=0.260). Most participants (77.6%) had good sleep quality based on PSQI assessment. Interestingly, a significant association was observed between high-sodium food consumption habits and sleep quality (p=0.000)Conclusion: High sodium dietary habits are associated with poor sleep quality among young adults. These findings highlight the importance of monitoring the daily sodium intake and reducing the consumption of sodium-rich foods to support better sleep quality and overall health.
Comparative analysis of stromal inflammatory cell infiltration and HPV infection status in cervical dysplasia and squamous cell carcinoma using the Klintrup-Mäkinen Scoring method Nicholas Adrian Fahendra; Daniel Edbert; Christian Ardianto; Lilis Lilis
Majalah Obstetri & Ginekologi Vol. 33 No. 3 (2025): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I32025.188-194

Abstract

HIGHLIGHTS KM score is a reliable method to help determine the diagnosis of cervical dysplasia and squamous cell carcinoma. KM score cannot be used to differentiate infection status in cervical dysplasia and squamous cell carcinoma.   ABSTRACT Objective: Cervical cancer is the second most common malignancy in women, with 604,127 new cases reported globally in 2020. Persistent high-risk human papillomavirus (HPV) infection is the primary cause. This study aimed to evaluate the relationship between stromal inflammatory cell infiltration using the Klintrup-Mäkinen (KM) score and HPV infection status in cervical dysplasia and squamous cell carcinoma (SCC). Materials and Methods: A cross-sectional study was conducted using secondary data from formalin-fixed paraffin-embedded (FFPE) cervical tissue samples diagnosed as dysplasia or SCC at Atma Jaya Catholic University of Indonesia from 2014 to 2022. HPV status was determined using PCR-based assays, while stromal inflammatory cell infiltration was assessed microscopically at 100× magnification and graded according to the KM scoring system by two blinded observers. Statistical analyses, including Chi-square and Spearman’s correlation tests, were performed using STATA/IC 15, with p < 0.05 considered significant. Results: A total of 38 samples were analyzed, comprising 20 (52.63%) cases of dysplasia and 18 (47.37%) cases of SCC. HPV positivity was identified in 70% of dysplasia and 94.44% of SCC cases. KM scores of 2/3, indicating moderate to severe inflammatory infiltration, were significantly more frequent in SCC (77.78%) compared to dysplasia (20%), showing a strong association with pathological diagnosis (p = 0.0019). However, no significant correlation was observed between KM score and HPV status in either lesion type. Conclusion: The KM scoring method provides a reliable and cost-effective approach for assessing stromal inflammatory cell infiltration in cervical lesions, aiding histopathological diagnosis, although it does not predict HPV infection status.
Co-Authors Andrijono Andrijono Anthony Andrew Gunarso Christian Ardianto Daniel Edbert Ignatio Rika Haryono Jessica Putri Sudarman Nawanto Agung Prastowo Nicholas Adrian Fahendra Nurjati Chairani Siregar Poppy Kristina Sasmita Prissilia Nanny Djaya Vetinly