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All Journal The Indonesian Biomedical Journal JNKI (Jurnal Ners dan Kebidanan Indonesia) (Indonesian Journal of Nursing and Midwifery) Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Lilis Lilis
Atma Jaya Catholic University Of Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health Other

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The Association of Parametrial Invasion with the Expression of Vascular Endothelial Growth Factor-C and Other Factors in Squamous Cell Cervical Carcinoma Stage IB and IIA Lilis Lilis; Nurjati Chairani Siregar; Andrijono Andrijono
The Indonesian Biomedical Journal Vol 11, No 3 (2019)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v11i3.838

Abstract

BACKGROUND: The presence of parametrial invasion in early stage squamous cell cervical cancer (SCCC) indeed indicates worse prognosis and need more adjuvant treatment. This study aimed to investigate the association between parametrial invasion and clinicohystopathology variables.METHODS: This retrospective study used specimens of squamous cell carcinoma stage IB-IIA. The inclusion criteria were cervical cancer stage IB-IIA and post radical hysterectomy with lymph node dissection and exclusion criteria was damaged and or insufficient histological preparations. The clinicohystopathology variables included age, tumour size and stage, differentiation and inflammation grade, lymphatic vascular and parametrial invasion, and lymph node metastasis. Histopathology staining, immunohistochemistry examination, and vascular endothelial growth factor-C (VEGF-C) expression were evaluated according to the standard procedure. The independent-T, Chi square, and Fisher’s exact test were applied to evaluate the association. The significance was set at p<0.05.RESULTS: Seventy-five cases were eligible. Parametrial invasion was found in 15 cases (20%). Three variables demonstrated a significant association with parametrial invasion, tumor size >4 cm (OR 4.32, 95% CI 1.29-14.38, p=0.01), lymphatic node metastasis (OR 3.90, 95% CI 1.17-13.03, p=0.02), and VEGF-C (OR 0.75, 95% CI 0.65- 0.87, p=0.03).CONCLUSION: Tumor size of >4 cm and lymph node metastasis (LNM) had a higher risk of parametrial invasion in SCCC stage IB-IIA.KEYWORDS: cervical carcinoma, parametrial invasion, vascular invasion, peritumoral stroma, VEGF-C expression
Menstrual Cycle Length and Dysmenorrhea in Female Adolescents Aged 9-18 Years Agnes Monica; Lilis; Felicia Kurniawan; Astrid Fransisca Padang
Indonesian Journal of Obstetrics and Gynecology Volume 11 No. 1 January 2023
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v11i1.1674

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Abstract Objective: To determine the relationship between menstrual cycle length and dysmenorrhea in female adolescents aged 9-18 years in Sang Timur Tomang School West Jakarta. Methods: This study used a cross-sectional study approach to conduct observational analytic research. The study samples were female students aged 9-18 years in Sang Timur Tomang School. Study data were obtained through the Verbal Multidimensional Scoring System (VMSS) questionnaire in Indonesian. The Chi-square test of independence was used to determine the relationship between menstrual cycle length and dysmenorrhea. Results: From a total of 137 respondents, 38% have abnormal menstrual cycle length. Eighty-two-point-seven percent of respondents who have abnormal menstrual cycle length experienced dysmenorrhea, and 17,3% of participants who have abnormal menstrual cycle length did not experience dysmenorrhea. Chi-square test results showed a significant relationship between menstrual cycle length and dysmenorrhea in female adolescents aged 9-18 years in Sang Timur Tomang School West Jakarta (p = 0,005). Conclusion: There is a significant relationship between menstrual cycle length and dysmenorrhea in female adolescents aged 9-18 years in Sang Timur Tomang School West Jakarta. Keywords: female adolescents, dysmenorrhea, menstrual cycle, menstrual cycle length
The effect of Hatha Yoga on pain intensity in severe primary dysmenorrhea among students: A randomized controlled trials Ignatio Rika Haryono; Jessica Putri Sudarman; Nawanto Agung Prastowo; Lilis Lilis
JNKI (Jurnal Ners dan Kebidanan Indonesia) (Indonesian Journal of Nursing and Midwifery) Vol 11, No 1 (2023)
Publisher : Alma Ata University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21927/jnki.2023.11(1).95-105

Abstract

Background: Yoga has been known as an alternative therapeutic modality for reducing pain. The benefits of yoga for reducing pain have been proven. Women often suffer pain due to dysmenorrhea. The effect of Yoga on dysmenorrhea pain has not been widely studiedObjectives: This study aimed to investigate the effect of hatha yoga on pain in primary dysmenorrhea (PD). Methods: This was a randomized controlled study (RCT) involving 50 female students, 25 each in control (C) and yoga group (Y). PD was diagnosed by Working ability, Location, Intensity (Wong-Baker scale), and Days of the Pain of Dysmenorrhea (WaLIDD) questionnaire. Pain intensity was assessed by the Numeric Rating Scale (NRS). Hatha yoga training was conducted for 12 weeks. The unpaired t-test, ANOVA and Tukey post hoc, and Pearson correlation test was applied. Significance was set at p<0.05. Results: The characteristics between groups were not different. ANOVA indicated the NRS score in control was not changed, while yoga was diminished (p=0.02). Tukey post hoc showed that the second and third NRS were lower than basal NRS (p=0.038 and 0.01, respectively). The third was also lower than the second NRS (p=0.039). The second and the third NRS in yoga were lower than in control (p=0.027 and <0.01, respectively). The second magnitude of change of NRS was significantly different from the first in yoga (1.92 ±2.4 vs. 3.09 ± 2.8, p=0.018). The magnitude of NRS changes in the first (0.06±1.1 vs. 1.92±2.4, p=0.013) and second (0.02 ± 1.6 vs. 3.09 ± 2.8, p= 0.004) in yoga was significantly greater than the control. NRS score was not correlated with age, BMI, and age of menarche. Conclusions: Hatha yoga exercise ameliorate pain intensity in primary dysmenorrhea among female university students.
Co-Authors Agnes Monica Andrijono Andrijono Astrid Fransisca Padang Felicia Kurniawan Ignatio Rika Haryono Jessica Putri Sudarman Nawanto Agung Prastowo Nurjati Chairani Siregar