Article Per Year (5 Year)
p-Index From 2020 - 2025
0.23
P-Index
This Author published in this journals
All Journal Buletin Peternakan Jurnal Veteriner The Indonesian Biomedical Journal
Indra Lesmana
Department Of Tropical Biology, Faculty Of Biology, Universitas Gadjah Mada, Jl. Teknika Selatan, Sekip Utara, Yogyakarta
Biochemistry, Genetics & Molecular Biology Public Health Veterinary Other

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
Growth Performance, Histological Structure of Duodenum and Pectoralis Muscle of Kampung Chickens After Administration of Antibiotic Growth Promoter Hendry Trisakti Saragih; Suci Aulia Ratu Fajrin; Sovia Nur Janah; Ria Oktafianti; Elgio Venanda Ginting; Anisa Fatwa; Stephanus Ardi Dimarjati; Indra Lesmana
Buletin Peternakan Vol 42, No 2 (2018): BULETIN PETERNAKAN VOL. 42 (2) MAY 2018
Publisher : Faculty of Animal Science, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21059/buletinpeternak.v42i2.29766

Abstract

This study aimed to know the effect of AGP on growth performance, duodenal histological structure and pectoralis muscle of Kampung chicken. This research was conducted by designing 3 groups with each group consisting of 20-day old chicks (DOC) of Kampung chickens. The control group was given basal feed without AGP bacitracin, group 2 was treated with 0.125 g of bacitracin /kg of basal feed and group 3 was treated with 0.25 g bacitracin/kg of basal feed until 12 days old. The parameters observed were chicken body weight on days posthatch, 3, 5, 7, 9, and 12, morphometry, visceral organ weight, duodenal organ morphology and muscle performance of Pectoralis thoracicus at 12 days old. Data analysis used one way ANOVA test followed by Tukey test with significance of P≤ 0,05. The result showed that the morphology of the doudenum and the myofiber area of group 3 indicated significant differences compared to the control group. The conclusion of this study revealed that administration of AGP bacitracin with 0.25 g/ kg dose of basal feed may increase the growth performance of Kampung chicken.
Pakan Aditif Ekstrak Etanol Lumut Hati Meningkatkan Pertumbuhan Morfologi Duodenum dan Perkembangan Otot Dada Ayam Pedaging (SUPPLEMENTATION OF ETHANOLIC EXTRACT OF MARCHANTIA IN PRE-STARTER DIET IMPROVES THE GROWTH OF DUODENUM AND PECTORALIS THORACICUS Hendry Tri Sakti Surya Gunawan Saragih; Muhammad Faisal Alawi; Muhammad Rafieiy; Indra Lesmana; Heri Sujadmiko
Jurnal Veteriner Vol 18 No 4 (2017)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (116.81 KB) | DOI: 10.19087/jveteriner.2017.18.4.617

Abstract

This study aimed to determine the effectiveness of ethanolic extract of Marchantia as an alternative additive in broiler’s chicken feed. The research was designed by using 5 treatment groups with 20 day-old chick broilers in each group and the treatment was done until the sample aged 14 days. The treatment groups consisted of basal feed and ethanolic extract of Marchantia in 0; 62.5; 250; 500; 1000 mg/kg basal feed. Data were analyzed by using one way ANOVA test followed by Tukey test with significance P<0.05. The results showed that at 14 days old of the sample, the weight gain of the broilers in the treatment group 1, 2, 3, and 4 were higher than the control group; Feed Conversion Ratio of treatment group 4 was better than the control group and other treatments; the small intestine morphology of villus heights, crypt depth, and villus/crypt ratio showed that the treatment group 3 and 4 were better than the control group; the pectoralis muscle’s weight, muscle’s area, and myofiber’s area showed that the treatment group 1 and 3 were better than the control group. The study indicates that the ethanolic extract of Marchantia spp. with concentration of 750-1000 mg/kg basal feed has effective ability as an alternative additive in broiler’s chicken feed.
Splice-site and Frameshift Mutations of β-Globin Gene Found in Thalassemia Carrier Screening in Yogyakarta Special Region, Indonesia Niken Satuti Nur Handayani; Nailil Husna; Gunawan Rahmil; Riris Anindya Ghifari; Lily Widyawati; Indra Lesmana
The Indonesian Biomedical Journal Vol 13, No 1 (2021)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v13i1.1406

Abstract

BACKGROUND: β-thalassemia is an inherited blood disorder that relatively common in Southeast Asian countries. In Indonesia, it is estimated that 200,000 infants with thalassemia carrier born each year. Mutation causing β-thalassemia is highly varied and relatively specific in a population. This study aimed to identify the mutations responsible for β-thalassemia from Thalassemia Carrier Screening conducted in Yogyakarta Special Region. This information is beneficial for developing a strategic prevention program to control thalassemia in the region.METHODS: Twenty-eight blood samples of haematologically suspected β-thalassemia from participant of thalassemia screening program in Yogyakarta Special Region were investigated for β-globin gene mutation by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP), amplification refractory mutation system (ARMS) and DNA sequencing.RESULTS: Our samples showed average HbA2 value of 5±0.81% and HbF value of 2±2.29%. It showed eight abnormal erythrocyte morphologies dominated by hypochromia (96.4%), cigar cell (85.7%), and microcytosis (78.6%). Our molecular investigation identified three splice-site mutations namely InterVening Sequence (IVS)-1-5 (G>C) (71.4%), IVS-1-2 (T>C) (7.1%), and IVS-1-1 (G>T) (3.6%), two frameshift mutations that are CD35 (-C) (10.7%) and CD8/9 (+G) (3.6%), and a missense mutation of CD6 (GAG>GTG) (3.6%).CONCLUSION: Our study concluded on a high prevalence of IVS-1-5 (G>C) mutation in Yogyakarta Special Region. This mutation information is significant for developing a strategic prevention program to control thalassemia in the region, for example for developing a rapid molecular test for future screening program.KEYWORDS: β-Globin gene, thalassemia, screening, carrier, mutation, Yogyakarta
Co-Authors Anisa Fatwa Elgio Venanda Ginting Gunawan Rahmil Hendry Tri Sakti Saragih Hendry Tri Sakti Surya Gunawan Saragih Heri Sujadmiko Lily Widyawati Muhammad Faisal Alawi Muhammad Rafieiy Nailil Husna Niken Satuti Nur Handayani Ria Oktafianti Riris Anindya Ghifari Sovia Nur Janah Stephanus Ardi Dimarjati Suci Aulia Ratu Fajrin