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All Journal journal of internal medicine Jurnal Kedokteran Brawijaya Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML)
Putu Moda Arsana
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience

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A CASE OF METHANOL INTOXICATION COMPLICATED WITH ACUTE PANCREATITIS, ALCOHOLIC KETOACIDOSIS, AND INTRACEREBRAL HEMORRAGE Rahardi, Eric; Moda Arsana, Putu
journal of internal medicine Vol. 12, No. 3 September 2011
Publisher : journal of internal medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (152.101 KB)

Abstract

Methanol intoxication occurs after accidental or suicidal ingestion occasionally and the toxicity is due to the formationof formaldehyde and formic acid. Methanol ingestion can also lead to acute pancreatitis, a sudden in! ammation of thepancreas, and high metabolic acidosis as a complication. Brain injury in methanol intoxication could be ischemia orhemorrhage form. Therefore we?d like to present a report a male with methanol intoxication with several complicationsuch, acute pancreatitis, alcoholic ketoacidosis, and CVA-ICH. The patient presented with hemodynamic instability andsevere metabolic acidosis with pH 6.991. The anion gap was 30 mmol/l. Amylase was 187 U/l and CT scan showed intracerebralhemorrhage at right fronto temporo parietal lobe with peri-focal edema (volume 48 cc). Patient unfortunatelydied three days later after force discharge by his families. Brain injury in methanol toxicity is characterized by lesionsaffecting both basal ganglia and subcortical regions. The lesion could be ischemia/necrosis or hemorrhage, selectivelyaffecting the putamenal bilaterally.
PENGARUH RESTRIKSI KALORI TERHADAP KADAR HIDROGEN PEROKSIDA DAN KADAR GLUKOSA DARAH PADA TIKUS TUA E. Harianja; Anik Widijanti; Putu Moda Arsana; K. Handono
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 14, No 1 (2007)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v14i1.921

Abstract

Aging is a syndrome of progressive, universal and irreversible alterations. Endocrinology alterations in aging consist of insulin resistance, hyperinsulinemia, increase of hydrogen peroxide and glucose blood level. At the beginning of aging process the Pancreaticcellsproducemoreinsulininorderiskeepbloodglucosewithinnormallevel.Butthepersistentofhyperglycemiaconditioncausedthepancreatic-cellsunabletoproduceadequateinsulinduetointernalfactorsorexternalfactors.Asthisconditionprogress,wouldbedisturbedfastingandpost-prandialbloodglucose(hyperglicemia).Besidesinsulinresistance,freeradicalsalsoincreasedasaconsequenceoffailurecompensationofcellsinthebody.TheaimofthisstudyistodeterminethatintermittentanddailycalorierestrictioninoldmaleWistarratscanreduceserumhydrogenperoxide,andbloodglucoselevel.Themethodofthisstudywasanexperimentalstudywithpost-testcontrolgroupdesign.TwentyfourmaleWistarratsabout12monthsold,weredividedintofourequalgroupsandeachgroupcontainsixrats:(i)adlibitumfed(control),(ii)2-1intermittentwith2daysfedand1dayfast,(iii)1-1intermittentwith1dayfedand1dayfast,and(iv)40%continuouscalorierestrictioneveryday.Independentvariableinthisstudywascalorieintakeandbodyweight.Dependentvariableswerehydrogenperoxideleveland.Bloodglucoselevel.Thedifferenceofeachgroupwasanalyzedwithone way ANOVA and the least significant difference was analyzed by the use post hoc tests, using p < 0.05. The result of this study for hydrogen peroxide and blood glucose level in control group with experimental groups were p 0.000 and p 0.001. There was positivecorrelation between hydrogen peroxide level and blood glucose level r 0.791. We conclude that calorie restriction decrease hydrogenperoxide level and as well as regulating of blood glucose level. The best one of this method is 40% calorie restriction.
Clinical Response of Convalescent Plasma Therapy in COVID-19 Patients in Dr. Saiful Anwar General Hospital Niniek Budiarti Burhan; Herwindo Pudjo Brahmantyo; Djoko Heri Hermanto; Putu Moda Arsana
Jurnal Kedokteran Brawijaya Vol. 31 No. 4 (2021)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2021.031.04.5

Abstract

The use of convalescent plasma has been beneficial for more than a century to treat various infections.  The lack of effective treatment currently available for COVID-19 has reemerged the use of convalescent plasma as a potential therapeutic option. This is an observational descriptive study in 13 COVID-19 patient who got convalescent Plasma. Consist of 11 (84%) male patient, 2 (16%) female patient. Divided into two groups based on severity, and outcome. 38% patient included in severe disesase and 62% patient in critically Ill condition. 30% patient who got convalescent plasma deceased, and 70% had a resolve condition.
Co-Authors Anik Widijanti Brahmantyo, Herwindo Pudjo Djoko Heri Hermanto E. Harianja Eric Rahardi K. Handono Niniek Budiarti B