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All Journal Jurnal Kedokteran Brawijaya CRJIM (Clinical and Research Journal in Internal Medicine)
Brahmantyo, Herwindo Pudjo
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Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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DERAJAT DEPRESI PASIEN HEPATITIS C KRONIS YANG MENDAPAT TERAPI PEGIFN-α Indriyaningrum, Nurria Betty; Brahmantyo, Herwindo Pudjo; Mustika, Syifa
Jurnal Kedokteran Brawijaya Vol 29, No. 3 (2017)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2017.029.03.9

Abstract

Disamping efek dari infeksi hepatitis C, pengobatan hepatitis C dengan menggunakan pegylated interferon alfa dikatakan memiliki efek samping berupa depresi. Untuk mengevaluasi gejala depresi pada pasien hepatitis C yang mendapatkan terapi pegylated interferon alfa di divisi Gastroentero-hepatologi RSUD Dr. Saiful Anwar Malang. Penilaian depresi dilakukan 1 kali, dengan menggunakan kuisioner Patient Health Questionnaire 9 (PHQ-9). Penelitian ini dilakukan antara tahun 2014-2015. Seluruh pasien hepatitis C yang mendapatkan terapi dengan pegylated interferon alfa, diberikan formulir kuisioner dari Patient Health Questionnaire (PHQ-9) untuk dievaluasi kondisi depresi yang terjadi. Dari keseluruhan pasien berjumlah 24 pasien, didapatkan hasil berupa depresi minimal sebanyak 9 pasien (37,5%), depresi ringan sebanyak 12 pasien (50%), depresi sedang sebanyak 2 pasien (8,3%) dan depresi sedang-berat sebanyak 1 pasien (4,2%). Rerata usia pasien adalah 53,55±12,13 (dalam tahun), dengan rentang usia 30-73 tahun. Jumlah pasien pria sama dengan jumlah pasien wanita (masing-masing 12 orang). Rerata lama terapi adalah 17,78±11,88 (dalam minggu). Genotipe terbanyak adalah genotipe 1 (16 pasien, 66,67%). Manifestasi depresi yang terbanyak adalah kelelahan yang terus menerus dan penurunan nafsu makan. Penelitian membuktikan adanya gangguan depresi pada pasien-pasien hepatitis C yang mendapat terapi pegylated interferon alfa (pegIFN?). Penilaian kondisi mental sebelum memulai terapi dan setelah selesai terapi, perlu dilakukan secara rutin untuk menilai adanya efek samping yang perlu ditangani secara lebih lanjut.Kata Kunci: Derajat depresi, hepatitis C kronis, pegIFN?
Keterlambatan Diagnosis Diabetes Mellitus pada Kehamilan Brahmantyo, Herwindo Pudjo; Nurshanty, Ade; Sasiarini, Laksmi
Jurnal Kedokteran Brawijaya Vol 29, No. 3 (2017)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2017.029.03.18

Abstract

Prevalensi wanita dengan diagnosis Diabetes Mellitus (DM) meningkat sepanjang tahunnya termasuk dalam kehamilan. Kami laporkan kasus seorang wanita 36 tahun dengan persalinan anak pertama yang dikonsultasikan dengan peningkatan gula darah sesudah persalinan. Dari hasil anamnesa dan pemeriksaan fisik tidak didapatkan riwayat DM pada pasien dan keluarga yang dapat menjadi penyebab keterlambatan diagnosis DM pada kehamilan. Anamnesis, observasi dan hasil pemeriksaan laboratorium mengindikasikan potensi DM yang dimulai sebelum kehamilan namun tidak dikonfirmasi melalui skrining pemeriksaan gula darah pada kehamilan. Bayi yang dilahirkan mempunyai berat badan normal namun sempat mengalami hipoglikemia. Pasien diberikan terapi injeksi insulin basal dimulai pada dosis 6 iu dan dinaikkan bertahap menjadi 8 iu dan 10 iu, sesuai dengan hasil evaluasi hingga tujuan terapi tercapai. Kasus ini menunjukkan pentingnya penggalian riwayat dengan teliti dan skrining DM dalam kehamilan pada mereka yang berisiko untuk mencegah komplikasi pada janin maupun ibu. Kata Kunci: Diabetes mellitus, kehamilan, komplikasi 
Clinical Response of Convalescent Plasma Therapy in COVID-19 Patients in Dr. Saiful Anwar General Hospital Burhan, Niniek Budiarti; Brahmantyo, Herwindo Pudjo; Hermanto, Djoko Heri; Arsana, Putu Moda
Jurnal Kedokteran Brawijaya Vol 31, No 4 (2021)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2021.031.04.5

Abstract

The use of convalescent plasma has been beneficial for more than a century to treat various infections.  The lack of effective treatment currently available for COVID-19 has reemerged the use of convalescent plasma as a potential therapeutic option. This is an observational descriptive study in 13 COVID-19 patient who got convalescent Plasma. Consist of 11 (84%) male patient, 2 (16%) female patient. Divided into two groups based on severity, and outcome. 38% patient included in severe disesase and 62% patient in critically Ill condition. 30% patient who got convalescent plasma deceased, and 70% had a resolve condition.
Clinical Response of Convalescent Plasma Therapy in COVID-19 Patients in Dr. Saiful Anwar General Hospital Niniek Budiarti Burhan; Herwindo Pudjo Brahmantyo; Djoko Heri Hermanto; Putu Moda Arsana
Jurnal Kedokteran Brawijaya Vol. 31 No. 4 (2021)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2021.031.04.5

Abstract

The use of convalescent plasma has been beneficial for more than a century to treat various infections.  The lack of effective treatment currently available for COVID-19 has reemerged the use of convalescent plasma as a potential therapeutic option. This is an observational descriptive study in 13 COVID-19 patient who got convalescent Plasma. Consist of 11 (84%) male patient, 2 (16%) female patient. Divided into two groups based on severity, and outcome. 38% patient included in severe disesase and 62% patient in critically Ill condition. 30% patient who got convalescent plasma deceased, and 70% had a resolve condition.
Prevalence and Clinical Characteristics of Anemia Among Adults in a Highland Rural Community of East Java, Indonesia: Anemia in a Highland Village of East Java Nurarifah, Nina; Hermanto, Djoko Heri; Wardhani, Shinta Oktya; Brahmantyo, Herwindo Pudjo; Putri, Rakhmi Tika; Nainggolan, Freddy Chandra; Hapsari, Aulia Sita
Clinical and Research Journal in Internal Medicine Vol. 7 No. 1: Volume 7 No 1, May 2026
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2026.007.01.07

Abstract

Anemia is a persistent global health challenge, particularly affecting women of reproductive age and residents of rural regions. This descriptive cross-sectional study assessed the prevalence and clinical characteristics of anemia among adult residents of Ngadas Village, a highland community in East Java, Indonesia. A total of 57 adults (48 females, 9 males) participated in a single-day community screening conducted by the Faculty of Medicine, Brawijaya University. Data collection included structured questionnaires, clinical examinations, and hemoglobin testing using the Sinocare H101 analyzer. The mean hemoglobin level was 14.6 ± 1.7 g/dL, with an overall anemia prevalence of 7.0%, indicating mild public health significance according to WHO classification. Fatigue (35.1%) and dizziness (49.1%) were the most common symptoms, whereas clinical signs such as pallor and cheilitis were infrequent. Women of reproductive age predominated, yet no pregnant respondents were anemic, suggesting the possible effectiveness of iron–folate supplementation programs. Although dietary protein and iron intake appeared adequate, frequent tea and coffee consumption among women (62.5%) could inhibit non-heme iron absorption. The findings underscore the predominance of subclinical anemia and the need for routine hemoglobin screening and targeted nutrition education. Strengthening preventive strategies in rural highland communities remains essential to sustain low anemia prevalence and improve public health outcomes.
Co-Authors Alfiani, Nadia Ardiyanti, Putri Arsana, Putu Moda Dharmesta, Naya Adi Djoko Heri Hermanto Hapsari, Aulia Sita hermanto, djoko heri Hermanto, Djoko Heri Indriyaningrum, Nurria Betty Nainggolan, Freddy Chandra Niniek Budiarti B Nurarifah, Nina Nurshanty, Ade Putri, Rakhmi Tika Putu Moda Arsana Qhadafy, Arif Sasiarini, Laksmi Shinta Oktya Wardhani, Shinta Oktya Syifa Mustika