mimik murukmihadi
Unknown Affiliation

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

FORMULASI SALEP EKSTRAK ETANOLIK DAUN BINAHONG (Anrederacordifolia (Ten.) Steenis) DENGAN VARIASI BASIS SALEP Elya Zulfa; Tegar Bagus Prasetyo; Mimik Murukmihadi
Jurnal Ilmu Farmasi dan Farmasi Klinik Jurnal Ilmu Farmasi & Farmasi Klinik Volume 12 No.2 Desember 2015
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (391.234 KB) | DOI: 10.31942/jiffk.v12i2.1411

Abstract

ABSTRACT The absorbtion-based ointment of ethanolic extract of binahong leaves  (Anredera cordifolia (Ten.) Steenis) on 10% concentrate has antibacterial activity towards Staphylococcus aureus. In order to improve the activity of this ethanolic extract of binahong leaves,  it is necessarily to adjust the ointment’s base of formulation. The aims of study are to determine the ointment’s physical characteristics  which various base such as hydrocarbon, absorbtion and water solubility. The ethanolic extract of binahong leaves obtained from maceration method, using 70% of ethanol. The ointment was made based on the variation of its base which are hydrocarbon, absorbtion and water solubility. The obtained oinment then was examined on its physical  characteristics  properties including organoleptic test, pH, viscosity, stickiness, spreadability, and antibacterial activity toward Staphylococcus aureus on the agar plate medium. The organoleptic and pH test result data were analyzed descriptively. The data of stickiness, viscosity were analyzed using one-way ANOVA and Tukey with the level of confidence up to 95%, whilst the spreadability data was analyzed using Kruskal wallis and Man whitney. There were significant differences between the results of viscosity, stickiness, on each formula of ethanolic extract ointment of binahong leaves. However, there were no significant differences on the pshycal characteristic of the pH, organoleptic, homogenic, and spreadability.  Keywords: Ointment, Binahong leaves, Antibacterial activity, Staphylococcus aureus.
PENGARUH PERBEDAAN KONSENTRASI EKSTRAK ETANOLIK UMBI BENGKUANG (Pachyrrhizus erosus, Urb) DALAM SEDIAAN KRIM TERHADAP SIFAT FISIKNYA yulias ninik windriyati; diah pitaloka wahyuningrum; mimik murukmihadi
Jurnal Ilmu Farmasi dan Farmasi Klinik JURNAL ILMU FARMASI DAN FARMASI KLINIK VOL. 4 NO. 1 JUNI 2007
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (94.545 KB) | DOI: 10.31942/jiffk.v4i1.830

Abstract

ABSTRACTPeople has been used juicy tuber as food and cosmetic for delicated skin. Juicy tuber extract was formulated in cream in order to practical and effective. The aim of this research is to know the influence of difference concentration of juicy tuber extract in cream and storage duration to its physical properties. Extract was obtained from juicy tuber by remaceration method using 70% ethanol. Cream were made in five formulas with extract concentration 0,5 %, 1,0 %, 1,5 %, 2,0 % and 2,5 % w/w using standard formula cold cream. The physical stability of the cream was tested such as homogeneity, creaming and cracking, stickness, and spreadibility for 4 weeks storage. The data obtained were statistically analyzed using Friedman test with the 95 % confident level, followed by Mann Whitney test. Result of this research indicate that the cream of juicy tuber extract homogeneous and no creaming for 4 weeks storage. The difference of extract concentration and storage duration had not influence to physical stability of cream. Keyword: Extract of Juicy tuber, Cream, Physical TestPENDAHULUANPerawatan kesehatan dan kecantikan dengan memanfaatkan bahan alamiah selain lebih murah juga lebih aman dan tidak menimbulkan efek samping yang membahayakan. Berbagai hasil penelitian dibidang kosmetik mengungkapkan bahwa perawatan kecantikan kuno dengan bahan alamiah bisa dibuktikan secara ilmiah (Surtiningsih, 2005).Kosmetika pada prinsipnya adalah obat namun tujuan pemakaiannya sedikit mengalami perubahan bila dibandingkan dengan tujuan pemakaian obat-obatan pada umumnya. Kosmetika dirancang untuk tujuan estetika yaitu mempercantik, memperbaiki, dan mengubah penampilan seseorang (Depkes RI., 2003).Tanaman bengkuang (Pachyrrhizus erosus, Urb) biasa dimanfaatkan sebagai buah atau bagian dari beberapa jenis masakan. Bengkuang juga dimanfaatkan sebagai penghalus kulit, dan berkhasiat sebagai obat beri-beri, demam, diabetes, sariawan dan wasir. Sifat kimiawi dan efek farmakologis tanaman bengkuang adalah manis, dingin, sejuk dan berkhasiat mendinginkan. Kandungan kimianya adalah Pachyrhiton, rotenone, vitamin B1 dan C (Anonim, 2003).Bengkuang supaya mudah digunakan sebagai penghalus kulit perlu dilakukan pengembangan formulasinya dalam sediaan krim. Penelitian ini bertujuan untuk mengetahui pengaruh perbedaan konsentrasi ekstrak etanolik umbi bengkuang dalam sediaan krim dan lama penyimpanan terhadap sifat fisiknya.METODOLOGIAlat