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Olivia H Naibaho,
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Medicine & Pharmacology

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PENGARUH BASIS SALEP TERHADAP FORMULASI SEDIAAN SALEP EKSTRAK DAUN KEMANGI ( Ocimum sanctum L.) PADA KULIT PUNGGUNG KELINCI YANG DIBUAT INFEKSI Staphylococcus aureus Naibaho,, Olivia H; Yamlean, Paulina V. Y.; Wiyono, Weny
PHARMACON Vol 2, No 2 (2013): pharmacon
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.2.2013.1553

Abstract

The basil plant (Ocimum sanctum L.) contains alkaloids, triterpenoids, flavonoids are able toprovide an antibacterial effect.The aims of this research were to study ointment base effectagainst physical properties and antibacterial effect of basil leaf extract ointment on Rabbits(Oryctolagus cuniculus) back skin infected with staphylococcus aureus.Extraction was doneby soxhlet extraction using ethanol 95% as solvent.Observation of healing time was done byobserving infectionhealingtime on rabbits back skin after anointment treatment, which basedonthe disappearance oferythema and pus. The result shows differences ointment base effectedon the physical properties of an ointment which include shape, color, pH, and dispersivepower, but had no effect on the smell and homogeneity of the preparation. Basil leavesextract ointment with base type hydrocarbons provide healing infections more quickly,followed by the type of water-soluble base, absorption, and washable base.Keywords: Base ointment, basil (Ocimum sanctum L.), Staphylococcus aureus, rabbit
Co-Authors Paulina yamlean Weny Wiyono