Article Per Year (5 Year)
p-Index From 2021 - 2026
0
P-Index
This Author published in this journals
All Journal Research Journal of Life Science
Karyono Mintaroem
Departement of Pathology Anatomy, University of Brawijaya
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Effect of Endurance Treadmill Training on mIGF-1 Expression and PAX 7 Satellite Cell in Rat Muscle Tissues Mustofa Mustofa; Karyono Mintaroem; Agustina Endharti
Research Journal of Life Science Vol 5, No 2 (2018)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (325.983 KB) | DOI: 10.21776/ub.rjls.2018.005.02.1

Abstract

This study examined the effects of endurance exercise training on muscle Insulin Growth Factor-1 (mIGF-1) and PAX7 transcription factor of satellite cell activation in a tibialis anterior muscle of rat. Rat were subjected to treadmill, divided into three groups, each containing 6 rats. Groups of high, moderate and low doses of exercise received 28, 17 and 12 m/s of treadmill speeds respectively. Treadmill exercise training conducted in 5 days a week within 9 weeks. At the end of 9 weeks of the experiment, rat were sacrificed, tibialis anterior muscle tissues was removed and then subjected to immunohistochemistry examination. There were significant differences in intensity of training in mIGF-1 and PAX7 in muscle tissues (P < 0.05). These results suggested that endurance exercise training which high, moderate and low intensity able to increase mIGF-1 and PAX7 that associates with satellite cell development of muscle tissues.
Co-Authors Agustina Endharti Mustofa Mustofa