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Yana M. Syah
Organic Chemistry Division, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung, Jalan Ganesha 10, Bandung 40132, Indonesia
Astronomy Chemistry Earth & Planetary Sciences Mathematics Physics

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Flavonoids from Macaranga lowii Widiastuti Agustina; Lia D. Juliawaty; Euis H. Hakim; Yana M. Syah
Journal of Mathematical and Fundamental Sciences Vol. 44 No. 1 (2012)
Publisher : Institute for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/itbj.sci.2012.44.1.2

Abstract

A new isoprenylated dihydroflavonol derivative, macalowiinin (1), together with two known flavonoids 4'-O-methyl-8-isoprenylnaringenin (2) and 4'-O-methyl-5,7,4'-trihydroxyflavone (3) (= acasetin), have been isolated from the methanol extract of the leaves of Macaranga lowii. The structures of these compounds were determined based on UV, NMR, and mass spectral data, and optical rotation. Preliminary cytotoxic evaluation of compounds 1 "“ 3 against P-388 cells showed that compound 3 is the most active with IC50 was 58.7 mM.
Co-Authors Euis H. Hakim Lia D. Juliawaty Widiastuti Agustina