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Journal : Journal Borneo

Pengelolaan sedıaan metadon pada Program Terapı Rumatan Metadon (PTRM) dı satelıt pelayanan PTRM Julaeha Julaeha; Nunung Priyatni; Rustamaji Rustamaji
Journal Borneo Vol. 2 No. 1 (2022): Volume 2 Issue 1 tahun 2022
Publisher : Politeknik Kaltara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (385.674 KB) | DOI: 10.57174/jborn.v2i1.17

Abstract

Methadone is a type of synthetic narcotic that is used as substitution therapy in the Methadone Maintenance Therapy Program (MMTP). Therefore, methadone must be treated as narcotics in general. Pharmacists in MMTP have responsibility for the management of methadone. This study aims to evaluate the suitability of the management of methadone preparations at the MMTP satellite service in the Special Region of Yogyakarta (DIY) based on the MMTP guidelines issued by the Ministry of Health which include requests, storage, dispensing, and reporting of methadone use. This study is a mixed-methods study (qualitative and quantitative) with prospective data collection. The quantitative measurement instrument in the study was in the form of a checklist table for the suitability of methadone management based on applicable guidelines. Qualitative data sourced from interviews with MMTP officers. The results of this study indicate that the demand, storage, and reporting of the use of methadone are in accordance with the MMTP service guidelines. However, for the dispensing of methadone on the MMTP service satellites, it is still carried out by health workers other than pharmacists.
Laporan kasus selulitis pedis pada diabetes melitus tipe 2 dengan terapi antibiotik dan insulin Julaeha Julaeha; Nadya Farisma
Journal Borneo Vol. 2 No. 1 (2022): Volume 2 Issue 1 tahun 2022
Publisher : Politeknik Kaltara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (359.387 KB) | DOI: 10.57174/jborn.v2i1.18

Abstract

Diabetes mellitus (DM) is called the silent killer which can cause microvascular and macrovascular complications. Cellulitis is a form of microvascular complication of uncontrolled DM. A 49-year-old female patient came to the hospital with complaints of sores and pain in the right big toe. The patient has a history of type 2 diabetes mellitus, with the result of a current blood sugar level of 582 mg/dL. The patient received insulin therapy novorapid® and levemir®, paracetamol injection, ceftriaxone injection, metronidazole injection and amlodipine. From the results of monitoring drug therapy, administration of combination therapy with antibiotics and insulin is the right and safe choice of therapy in overcoming gangrenous infections with uncontrolled blood glucose conditions. However, in monitoring drug therapy, it was found that there was a potential for minor drug interactions between metronidazole and paracetamol. Metronidazole can increase the level or effect of paracetamol by affecting the metabolism of the liver enzyme CYP2E1 so there must be a delay in administration. Topical antibiotics should be considered in the long-term treatment of complications of cellulitis pedis in type 2 DM patients.
Potensi peningkatan efek sedasi dan gangguan ritme jantung pada pengobatan skizofrenia Julaeha Julaeha; Nurhaliza
Journal Borneo Vol. 2 No. 2 (2022): Volume 2 Issue 2 tahun 2022
Publisher : Politeknik Kaltara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (309.989 KB) | DOI: 10.57174/jborn.v2i2.26

Abstract

Skizofrenia paranoid merupakan tipe skizofrenia yang paling banyak diderita di berbagai negara.   Gejala psikosis yang dialami berupa delusi yang secara relatif stabil, seringkali bersifat paranoid, biasanya disertai dengan halusinasi, terutama halusinasi pendengaran, dan gangguan persepsi. Pasien “X” berumur 22 tahun dirawat dan didiagnosa skizofrenia paranoid dengan keluhan gelisa selama 4 hari terakhir, emosi labil, teriak-teriak, memukul, mengancam akan membunuh. Pasien mendapatkan terapi risperidon 2 mg, lorazepam 1 mg, trifluoferazin 5 m, dan olanzapin 5 mg. Masalah terkait obat yang ditemukan adalah adanya interaksi obat risperidon dengan lorazepam, yaitu dapat meningkatkan sedasi dan trifluoferazin dengan risperidon dapat memperpanjang interval QT. Pemantauan perbaikan gejala psikosis, efek sedasi dan gangguan ritme jantung perlu dilakukan utuk memastikan keberhasilan dan keamanan dari terapi yang diberikan.