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Physical Exercise in Clinical Stage IIhuman Immunodeficiency Virus Infection Patients’ Increasesskeletal Muscle MAss Through the Increasing of Myogenic Regulatory Factors Expression Sri Mardjiati Mei Wulan; Hening Laswati; Usman Hadi; Nasronudin Nasronudin
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.17091

Background: Human Immunodeficiency Virus infection is a chronic diseasethat threatensthe health ofmillionsof people inthe worldand causing disability. One of the factors that causedisabilityis HIVmusclewasting,causing a decrease inthe quality of lifethat interferethe daily activitiesand evenincreased mortality. Properphysical exercise is needed to prevent and treat muscle wasting.Methods: This studyusinghuman subjectswithclinicalstageII HIVinfection. Subjectswere groupedinto two:Intervention (n =9) that subjects whogetmoderate-intensity physicalexercise (HIVA) for 8weeks andControl (n=9) as subjects wereobservedfor 8 weeks. Muscles samples were taken fromthe vastuslateralismusclebiopsiesthat performed24 hoursafterthe lastphysical exercise,immunohistochemicalexaminationwithmonoclonalantibodyanti-Pax7, anti-MyoD1 andanti-myogenin and measurement of thigh circumference.Results: Therewere significant increase in regeneration of skeletal muscle in the intervention group(increasing of Pax7, MyoD1 and myogenin) than the control groupand significant increase in quadricepsmuscles mass as measured by thigh circumference (p < 0.001).Conclusion: HIVA physical exerciseof moderate intensityincreasesskeletal muscleregenerationinclinicalstageII HIVinfectionthroughthe increasingPax7, MyoD1, myogeninexpression and followed by an increaseof quadriceps muscles mass.

Effect of Power-Assisted Functional Electrical Stimulation (PAFES) and Occupational Exercise on Motor Unit Activity of Extensor Digitorum Communis and Hand Dexterity in Post-stroke Patient Yusuf Roni; Sri Mardjiati Mei Wulan; I Putu Alit Pawana
Surabaya Physical Medicine and Rehabilitation Journal Vol. 2 No. 2 (2020): SPMRJ, AGUSTUS 2020
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/spmrj.v2i2.17602

Background: Weakness of upper extremity can affect the ability to perform daily activities in post-stroke patients. Power-Assisted Functional Electrical Stimulation (PAFES) may give motor reeducation and sensory feedback to improve motor recovery through neuroplasticity.Aim: To evaluate the effect of PAFES and occupational exercise on post-stroke patient hand dexterity and motor unit activity of extensor digitorum communis muscle.Material and methods: Twenty post-stroke patients enrolled in the study were divided intervention group whom received PAFES and occupational exercise, and control group whom received occupational exercise only. Each group underwent 30 minutes per session of treatment, 5 times a week, for 3 weeks. The Root Mean Square (RMS) for measuring motor unit activity of extensor digitorum communis muscle; Box and Block Test (BBT) and Nine Hole Peg Test (NHPT) for measuring hand dexterity were evaluated before and after intervention.Result: There were significant improvements of RMS (p<0.001), BBT (p<0.001) and NHPT (p=0.002) in intervention group after receiving PAFES and occupational exercise. The improvement of BBT in intervention group was significant compared with control group (p=0.028), however, no significant improvement of NHPT was found between groups.Conclusion: PAFES and occupational exercise could improve motor unit activity of the extensor digitorum communis muscle and hand dexterity in post-stroke patient.

Effect of Inclination Changes in High-Intensity Interval Training on Quality of Life of Male with Overweight and Obesity natanael sinulingga; Sri Mardjiati Mei Wulan; Noor Idha; Sony Wibisono
Surabaya Physical Medicine and Rehabilitation Journal Vol. 5 No. 1 (2023): SPMRJ, FEBRUARY 2023
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/spmrj.v5i1.25661

Background: Overweight and obesity are major public health concerns globally and cause poor quality of life. Physical exercise plays a major role in reducing body weight, however, lack of time for exercise leads to a lack of regular exercise. High-intensity interval training (HIIT) is proposed as an alternative exercise in dealing with overweight and obesity and ultimately increases the quality of life. Aim: To proposed as an alternative exercise in dealing with overweight and obesity and ultimately increases the quality of life. Material and Methods: A randomized-controlled trial was conducted in a rehabilitation outpatient clinic. Twenty-two subjects with overweight or obesity were randomly allocated into the intervention and control group. The intervention group received HIIT using a treadmill (HR rest + 80-90% HR reserve) with inclination changes for 30 minutes (preceded by warming up and ending with cooling, 5 minutes each), 3 times a week, for 2 weeks. The Control group received no intervention. Change of quality of life was assessed by using SF-36 before and after the intervention. Results: Subjects’ baseline body height, body weight, BMI, VO2Max, and SF-36 on both groups showed no significant differences (p<0.05). Subjects in the control group are older than the intervention group (34.82±3.09 vs 30.36±2.58, p=0.002). Significant improvement of SF-36 was found only in domains of physical function in the intervention group (p=0.02). However,he between-group comparison analysis showed no difference of SF-36 Δ Value between groups. Conclusion: High-intensity interval training can be proposed as an exercise therapy option to improve the quality of life of males with overweight and obesity. It is necessary to do further research on HIIT with a larger number of samples, longer time, group training, and combined with other exercises.

Hubungan Manajemen Latihan dengan Parameter Pola Jalan pada Anak dengan Cerebral Palsy (CP) Sofiatun; Meilisa Puspita Handayani; Meyla Rossa; Sri Mardjiati Mei Wulan
Journals of Ners Community Vol 13 No 2 (2023): Journals of Ners Community
Publisher : Fakultas Ilmu Kesehatan Universitas Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55129/jnerscommunity.v13i2.2693

Background: Cerebral Palsy is a non-progressive disorder due to the presence of lesions in the brain. This affects the early development of the baby which affects the ability to move, balance, and posture. Cerebral Palsy is causes of children's motor disabilities, mostly in decreasing the flexibility of lower extremity muscles and affecting the pattern of walking in sufferers. Objectives: This study aims to identify the relationship between exercise management and the Dynamic Gait Index (DGI) as a parameter of walking patterns in children with cerebral palsy. Research Design: This study used a descriptive observational-analytical cross sectional study in 15 cerebral palsy patients aged 4 to 19 years with GMFCS I-II and had received an exercise program of at least 8 weeks. Data analysis using the Spearman test on SPSS Statistics 26.0. Result: Obtained the value of p = 0.001 (p < 0.01) and the correlation coefficient (ρ) = 0.848 on the relationship of exercise intensity and road pattern parameters. Conclusion: There is a relationship between exercise management and gait pattern parameters.

Fitness Level in Mojo VI Surabaya Elementary School Students Nabilah Ishanan Ramadhan; Hening Laswati; Kristanti Wanito Wigati; Sri Mardjiati Mei Wulan
Surabaya Physical Medicine and Rehabilitation Journal Vol. 5 No. 1 (2023): SPMRJ, FEBRUARY 2023
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/spmrj.v5i1.23767

Background: A sedentary lifestyle such as watching TV and video for a long time, or playing PlayStation, is experienced by two-thirds of children, especially in developing countries. The fitness levels of elementary school students are not all in a good condition. So far, there is no study of healthy children with 2-minute walk test method. Therefore, the researcher is interested to do research about fitness level with 2-minute walk test. Aim: The purpose of this research is to determine the fitness level of Mojo VI elementary school Surabaya. Material and Methods: The method used in this research is descriptive observational with a cross-sectional research design using total sampling. Data collection was using primary data obtained from the results of 2-minute walk test. Results: The fitness level based on age obtained the highest average value at the oldest age of 12 years old with an average of 207.30 m±17.359. While the lowest average value at the youngest age was 184.96 m±15.991. Meanwhile, based on gender, it obtained higher average value in male students (201.81 m±22.06 m) than female students (194.30 m±14.29 m). Conclusion: The higher the age, the higher the student's fitness level. Meanwhile, based on gender, the fitness level of a male is higher than a woman.

Comparison of the Effects of Repetitive Transcranial Magnetic Stimulation and Aerobic Exercise as an Adjunct Therapy in Depressed Patients on Activity of Daily Living and Quality of Life Muhammad Yusuf; Sri Mardjiati Mei Wulan; Reni Hendrarati Masduchi; Agustina Konginan
Surabaya Physical Medicine and Rehabilitation Journal Vol. 5 No. 1 (2023): SPMRJ, FEBRUARY 2023
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/spmrj.v5i1.25196

Background: Depression is one of the most common causes of disabilities and poor quality of life worldwide. One-fifth of patients fail to respond to antidepressant therapy. Hence, adjunct therapy is urgently needed. Aim: This study aims to compare the effectiveness of repetitive transcranial magnetic stimulation (rTMS) and aerobic exercise as adjunct therapy on activity of daily living and quality of life in depressed patients. Material and Methods: A randomized-controlled experiment was conducted between May 2019 and January 2020. Twenty-seven depressed patients were divided into three groups for two weeks: antidepressant-only, antidepressant-and-aerobic exercise, and antidepressant-and-rTMS. The Barthel Index and SF-36 were used to assess the activity of daily living and quality of life. Results: After the intervention, there were no appreciable changes in the Barthel Index scores in any of the three groups (p>0.05). Following therapy, SF-36 results for physical function, bodily discomfort, public health, vitality, social function, emotional role functioning, and mental health all showed substantial improvements across groups (p 0.05). Patients in the antidepressant and rTMS groups improved more than those in the other two groups in the areas of overall health (15.71±6.075, p=0.009), emotional role functioning (20.29±11.940, p=0.049), and mental health (14.29±6.075, p=0.041). However, the Barthel Index score changes did not differ between groups (p=0.664). Conclusion: Better quality of life improvement in the rTMS group compared to the other two groups supports the use of rTMS as an additional therapy. It aims to enhance quality of life in patients with moderate and severe first-episode depression.

Cross-Cultural Adaptation of Indonesian Version of Activities-Specific Balance Confidence Scale for Elderly in Surabaya Nuruzzaman, Andi; Satyawati, Rwahita; Mei Wulan, Sri Mardjiati
Folia Medica Indonesiana Vol. 56 No. 4 (2020): December
Publisher : Universitas Airlangga

Falling is a major health problem and is also a major cause of morbidity and mortality in the elderly. The more serious consequences of falling on the elderly are the increased risk of injury and fear of falling. Activities-Specific Balance Confidence (ABC) scale is one of the assessment instruments for fear of falling. This instrument is used to assess balance confidence in various ambulation activities. The purpose of this study was to carry out the process of adaptation of the cross cultural ABC English questionnaire to ABC Indonesian. This study was a cross sectional study with participants of five elderly members of the Posyandu Lansia who were in accordance with the inclusion and exclusion criteria. The output is the correlation between the score of ABC English with ABC Indonesian and the score of ABC Indonesian with ABC English Back Translation which are tested at different times. All the question score in the ABC English questionnaire correlated with ABC Indonesian, as well as the Indonesian Language ABC correlated with ABC English back translation, have a significant correlation (r> 0.3). The conclusion of this study is that the ABC English has a close meaning with the ABC Indonesian and the ABC Indonesian has a close meaning with the ABC English back translation. The validity and reliability of the Indonesian version of ABC questionnaire is needed to obtain a valid and reliable questionnaire.

Hubungan Manajemen Latihan dengan Parameter Pola Jalan pada Anak dengan Cerebral Palsy (CP) Sofiatun; Meilisa Puspita Handayani; Meyla Rossa; Sri Mardjiati Mei Wulan
Journals of Ners Community Vol 14 No 2 (2023): Journals of Ners Community
Publisher : Fakultas Ilmu Kesehatan Universitas Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55129/jnerscommunity.v13i2.2693

Â Background: Cerebral Palsy is a non-progressive disorder due to the presence of lesions in the brain. This affects the early development of the baby which affects the ability to move, balance, and posture. Cerebral Palsy is causes of children's motor disabilities, mostly in decreasing the flexibility of lower extremity muscles and affecting the pattern of walking in sufferers. Objectives: This study aims to identify the relationship between exercise management and the Dynamic Gait Index (DGI) as a parameter of walking patterns in children with cerebral palsy. Research Design: This study used a descriptive observational-analytical cross sectional study in 15 cerebral palsy patients aged 4 to 19 years with GMFCS I-II and had received an exercise program of at least 8 weeks. Data analysis using the Spearman test on SPSS Statistics 26.0. Result: Obtained the value of p = 0.001 (p < 0.01) and the correlation coefficient (Ï) = 0.848 on the relationship of exercise intensity and road pattern parameters. Â Conclusion: There is a relationship between exercise management and gait pattern parameters.

Bone Adaptation Process on Post-menopausal Women after Speed Play Walking Exercise with Medium & High Increased Cadence Tinduh, Damayanti; Rosita, Primadita Esther; Mei Wulan, Sri Mardjiati
Surabaya Physical Medicine and Rehabilitation Journal Vol. 7 No. 1 (2025): SPMRJ, FEBRUARY 2025
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/spmrj.v7i1.59596

Background: Postmenopausal period is usually marked by dominancy of osteoclast activity, which leads to a decrease in bone mass. Speed Play Walking Exercise (SPWE) could be an important mechanical strategy for maintaining bone cell activity in postmenopausal women. Aim(s): This study evaluated the rate of increased cadence in SPWE, which can reduce bone resorption and increase bone formation activities, associated with body mass index. Material and methods: This was four group pre-post intervention design randomized clinical trial, included 32 postmenopausal women in normal-weight (NW) vs. overweight (OW) groups, divided into 2 groups of different walking speeds. The intervention is SPWE method with increased 15-35% or 50-80% from initial cadence as intervention target cadence, alternated with usual cadence, 3 times a week, for 4 weeks duration. Variables are baseline CTx and NMid osteocalcin serum taken on pre and post 4 weeks exercise. Result: sNMid osteocalcin was increased in groups walked with 15-35% increased cadence compared to group walked with 50-80% increased cadence (p=0.002 for NW group and p=0.042 for OW group, respectively). NW group walked with 50-80% increased cadence showed the most decreased bone formation marker (p=0.019). CTx/NMid ratio is reduced in NW group walked with 15-35% increased cadence, on the other hand, OW group walked with 50-80% increased cadence showed the most increased trend of CTx/NMid ratio. Conclusions: To maintain bone formation activity, SPWE with a rate of 15-35% increased from initial cadence is suggested for postmenopausal women, however the benefit is more visible in women with normal-weight.

Hubungan Manajemen Latihan dengan Parameter Pola Jalan pada Anak dengan Cerebral Palsy (CP) Sofiatun; Meilisa Puspita Handayani; Meyla Rossa; Sri Mardjiati Mei Wulan
Journals of Ners Community Vol 14 No 2 (2023): Journals of Ners Community
Publisher : Fakultas Ilmu Kesehatan Universitas Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55129/jnerscommunity.v13i2.2693

Â Background: Cerebral Palsy is a non-progressive disorder due to the presence of lesions in the brain. This affects the early development of the baby which affects the ability to move, balance, and posture. Cerebral Palsy is causes of children's motor disabilities, mostly in decreasing the flexibility of lower extremity muscles and affecting the pattern of walking in sufferers. Objectives: This study aims to identify the relationship between exercise management and the Dynamic Gait Index (DGI) as a parameter of walking patterns in children with cerebral palsy. Research Design: This study used a descriptive observational-analytical cross sectional study in 15 cerebral palsy patients aged 4 to 19 years with GMFCS I-II and had received an exercise program of at least 8 weeks. Data analysis using the Spearman test on SPSS Statistics 26.0. Result: Obtained the value of p = 0.001 (p < 0.01) and the correlation coefficient (Ï) = 0.848 on the relationship of exercise intensity and road pattern parameters. Â Conclusion: There is a relationship between exercise management and gait pattern parameters.

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