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The Benefits of Fasting to Improve Health Conditions and to Prevent Cardiovascular Disease Wahyu Sukma Samudera; Gracia Victoria Fernandez; Rahmatul Fitriyah; Hidayat Arifin; Shenda Maulina Wulandari; Roby Aji Permana
Jurnal Ners Vol. 14 No. 3 (2019): Special Issue
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jn.v14i3.17168

Abstract

Introduction: Fasting is defined as the voluntary abstinence from eating for variable time intervals and it has been associated with potential beneficial impacts on human health. The study was to review the benefits of fasting on cardiovascular health in humans with or without cardiovascular disease.Methods: The databases search was done using the keywords ‘fasting’ and ‘cardiovascular system’ using Scopus, Science Direct and ProQuest, limited to between 2013 and 2019 for publication year. A total of 3.619 articles were obtained and 15 articles involving experimental and non-experimental studies were used as the reference material.Results: The findings showed that in people who are healthy, fasting can reduce the inflammatory markers (IL-1 & IL-6, TNF-α), the oxidative stress marker (Malondialdehyde), body weight, abdominal circumference, fasting blood glucose, LDL, triglyceride and blood pressure. In people at risk or with cardiovascular disease, fasting can reduce body weight, body mass index, abdominal circumference, fat percentage, blood pressure, triglyceride, the biomarker of inflammation (serum amyloid A), the biomarker of oxidative stress (protein carbonyl), the biomarker of endothelial dysfunction (asymmetric dimethylarginine) and increase the vascular endothelial growth factor.Conclusion: Based on these findings, fasting can improve the health condition of people at risk or with cardiovascular disease by improving the risk factors such as blood pressure, overweight and endothelial dysfunction. In people who are healthy, fasting can be used for the prevention of cardiovascular disease by helping to maintain their weight, blood pressure, LDL and triglyceride within the normal limits.
Effect of Physical Exercise on Insulin Sensitivity and the Modifiable Cardiovascular Risk Factors of Patients with T2DM: A Systematic Review Wahyu Sukma Samudera; Ferry Efendi; Retno Indarwati
Jurnal Ners Vol. 15 No. 1Sp (2020): Special Issue
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jn.v15i1Sp.20521

Abstract

Introduction:  This study was undertaken to verify effect of regular exercise training on insulin sensitivity and the modifiable cardiovascular risk factors, and to determine if there was any effect from the different regular exercises. Methods: A database search using PRISMA examined articles from Scopus, ScienceDirect and ProQuest. The inclusion criteria were that the article used a randomized controlled trial within the last 10 years, that the respondents were people with type 2 diabetes mellitus and that only physical exercise was the intervention involved. In total, 1,303 articles were screened and 16 articles were included that fit the criteria of inclusion in this systematic review. Results: Based on the review of the 15 articles, the findings show that regular exercise training has some benefits related to glycemic control. It can reduce insulin resistance, plasma insulin, fasting blood glucose, postpandrial blood glucose and hbA1c. . Moreover, physical exercise has other benefits for people with type 2 diabetes mellitus, such as an increased peak oxygen consumption (VO2 peak) and decreased c-reactive protein (CRP) level. Conclusion: Regular exercise training has benefits for people with type 2 diabetes mellitus and it can allow them to achieve of optimal glycemic control by improving insulin resistance and decreasing the cardiovascular risk factors. Physical exercise such as combined exercises (aerobic and resistance exercise) or a single exercise such as aerobic exercise can be recommended to improve insulin sensitivity and the modifiable cardiovascular risk factors in patients with T2DM.
Hubungan Dukungan Keluarga Dengan Kepatuhan Minum Obat Pada Pasien Tuberkulosis Paru Endang Mei Yunalia; Idola Perdana Sulistyoning Suharto; Sri Haryuni; Samelina Eleeuw; Wahyu Sukma Samudera
Nursing Sciences Journal Vol 6, No 2 (2022): Oktober 2022
Publisher : Universitas Kadiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30737/nsj.v6i2.3730

Abstract

Angka kejadian tuberkulosis paru (TB Paru) di Indonesia masih masih cukup tinggi. Tingginya kejadian TB Paru salah satunya disebabkan karena masih rendahnya capaian pengobatan. Terlaksananya pengobatan pasien TB Paru memiliki kaitan dengan dukungan keluarga selama program pengobatan. Penelitian ini memiliki tujuan untuk mengetahui hubungan dukungan keluarga dengan kepatuhan minum obat pada pasien TB Paru. Metode penelitian yang digunakan adalah penelitian kuantitatif cross sectional dengan melibatkan 47 responden yang dipilih dengan menggunakan tekhnik consecutive sampling dan menggunakan kuesioner dukungan keluarga dan kuesioner Morisky Medication Adherence Scale-8. Selanjutnya data hasil penelitian dianalisis menggunakan uji Spearman Rank. Hasil penelitian menunjukkan bahwa hampir setengah responden dengan dukungan keluarga suportif memiliki tingkat kepatuhan pengobatan tinggi yaitu sebanyak 14 responden (29,8%), dan hampir setengah responden dengan dukungan keluarga non-suportif memiliki tingkat kepatuhan pengobatan sedang yaitu sebanyak 19 responden (40,4%) dengan p value = 0,000 <α = 0,05 dan nilai koefisien korelasi 0,801 yang artinya ada hubungan dukungan keluarga dengan kepatuhan minum obat pada pasien TB Paru. Berdasarkan hasil tersebut keluarga diharapkan agar mengikutsertakan keluarga dalam pengobatan pasien TB Paru.