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All Journal Journal of Agromedicine and Medical Sciences Jember Medical Journal (JMJ)
Kristianingrum Dian Sofiana
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Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Correlation of Cholinesterase Levels to Lung Function in Farmer Exposed by Organophosphate Pesticides in Sukorambi Village, Jember Regency Puput Sagita Mey Sandra; Kristianingrum Dian Sofiana; Ika Rahmawati Sutejo
Journal of Agromedicine and Medical Sciences Vol 5 No 2 (2019)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v5i2.9651

Abstract

Abstract Most of the Indonesia population work as a farmer. Pesticides are used in agriculture sector for pest and plant diseases. Pesticides can cause intoxication. The World Health Organization (WHO) estimates that 1-5 million cases of pesticides poisoning among agricultural workers occur in developing countries. Indonesia pesticide poisoning cases reach 771 cases. Organophosphate enter the body through inhalation. Organophosphate pesticides work systemic to inhibit the cholinesterase enzyme causing lung function disorders. The purpose of this study was to analyze the correlation of cholinesterase levels to lung function in farmers exposed to organophosphate pesticides in Sukorambi Village, Jember Regency. This is an observational analytic study using a cross sectional design. Cholinesterase levels test using the DGKC method to determine the presence of poisoning, while for lung function test using spirometry with FVC, FEV1 and FEV1 / FVC ratios as parameters. The results of the test in 30 samples showed 14.33% (4/30) abnormal cholinesterase levels or decreased. Lung function test showed 20% (6/30) had obstructive disorders, 43.33% (13/30) restrictive disorders and 36.67% (11/30) were normal. Data analysis using chi square showed a significant relationship (p = 0.049) between cholinesterase levels and lung function. Conclusion: There is a significant relationship between the level of cholinesterase to decrease in pulmonary physiology of farmers exposed to organophosphate pesticides in Sukorambi Village, Jember Regency. Keyword :Organophosphate, cholinesterase level, lung function
Perioperative Management on Septic Condition et Causa General Peritonitis: Case Report Handoko, Adelia; Gemawan, Taufiq; Muhammad Rizal Hadi Pratama; Kristianingrum Dian Sofiana; Amien, Muhammad Isryad
Jember Medical Journal Vol. 2 No. 2 (2023)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/jembermedicaljournal.v2i2.474

Abstract

Sepsis is a life-threatening systemic pathological condition. Based on WHO, there were 48.9 million cases with 11 million related deaths worldwide in 2017, which is almost 20% of all deaths from disease. Nearly half of all sepsis cases globally occurred in children, with an estimated 20 million cases and 2.9 million deaths. One of the conditions that can cause sepsis is generalized peritonitis. This study is a case report. Primary data was obtained through anamnesis, physical examination, laboratory test and radiology examination. In this case report, a 13-year-old child patient with generalized peritonitis was found due to obstructive ileus causing intestinal perforation, accompanied by sepsis, and underwent laparotomy and colostomy. Appropriate perioperative management is necessary to maintain hemodynamic stability and adequate oxygenation given the presence of sepsis in the patient.
Co-Authors Amien, Muhammad Isryad Handoko, Adelia Ika Rahmawati Sutejo Muhammad Rizal Hadi Pratama Puput Sagita Mey Sandra Taufiq Gemawan