Leni Santiana
Department Of Radiology, Faculty Of Medicine, Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital, Bandung

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

Hubungan Stadium Hipertensi dengan Derajat Perlemakan Menggunakan Indeks Hepatorenal Sonografi Dede Marina; Harry Galuh Nugraha; Leni Santiana; Lanny Noor Diyanti
Global Medical & Health Communication (GMHC) Vol 5, No 3 (2017)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (149.319 KB) | DOI: 10.29313/gmhc.v5i3.2175

Abstract

Hipertensi merupakan prekursor perkembangan perlemakan hati nonalkoholik. Modalitas pencitraan USG paling banyak digunakan untuk menegakkan diagnosis perlemakan hati nonalkoholik. Saat ini dikembangkan teknik USG menggunakan parameter indeks hepatorenal sonografi yang dihitung dengan program software ImageJ dan digunakan untuk memprediksi derajat perlemakan hati. Penelitian ini bertujuan mengetahui hubungan antara stadium hipertensi dan derajat perlemakan hati nonalkoholik menggunakan indeks hepatorenal sonografi. Penelitian menggunakan studi observasional analitik dengan rancangan cross sectional, pengambilan sampel dilakukan secara consecutive admission. Penelitian dilaksanakan di Bagian Radiologi RSUP Dr. Hasan Sadikin Bandung periode Juni–Agustus 2016. Subjek penelitian 50 orang, laki-laki 22 orang, perempuan 28 orang, usia termuda 25 tahun, dan tertua 77 tahun. Hasil penelitian melalui uji statistik chi-square menunjukkan derajat perlemakan hati nonalkoholik ringan lebih banyak pada prehipertensi (9 dari 16), derajat sedang pada hipertensi stadium I (10 dari 19), dan derajat berat pada hipertensi stadium II (8 dari 15) dengan p<0,001. Perlemakan hati nonalkoholik derajat sedang dan berat lebih sering ditemukan pada perempuan dengan hipertensi (p=0,005) Simpulan, terdapat hubungan antara stadium hipertensi dan derajat perlemakan hati nonalkoholik menggunakan indeks hepatorenal sonografi.THE ASSOCIATION OF HYPERTENSION STAGE AND NON-ALCOHOLIC FATTY LIVER DEGREE USING HEPATORENAL SONOGRAPHY INDEXHypertension is considered as a precursor to the development of non-alcoholic fatty liver disease (NAFLD). Ultrasonography techniques have been developed using sonography hepatorenal index parameter calculated by ImageJ, that can predict the degree of NAFLD. This study aim to determine the relationship between hypertension stage and the degree of NAFLD using sonography hepatorenal index. The research is an observational using cross sectional methods, with consecutive admission sampling method. The study was performed at Dr. Hasan Sadikin Hospital Bandung from June to August 2016. A total of 50 subjects, 22 men and 28 women, with the youngest 25 and the oldest 77 years old participated. Results  indicated that the mild degree of NAFLD were higher on prehypertension (9 of 16), the moderate degree on stage I hypertension (10 of 19), while the severe degree found on stage II hypertension (8 of 15), with p<0.001. Moderate and severe degree of NAFLD in hypertensive patient is more common in women (p=0.005). In conclusion, there was a relationship between hypertension stage and the degree of NAFLD. 
Comparative Study Gallbladder Contractility Index Using Ultrasound in Patients with and without Liver Cirrhosis Hari Soekersi; Leni Santiana; Fetty Fatmawaty
Global Medical & Health Communication (GMHC) Vol 8, No 1 (2020)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2781.261 KB) | DOI: 10.29313/gmhc.v8i1.3744

Abstract

Liver cirrhosis leads to impairment of gallbladder contractility resulting in bile stasis and facilitate the development of gallstones that will aggravate the clinical symptoms of the patients. The gallbladder contractility index is an indicator of gallbladder motility measured using ultrasound as the radiological choice of modality. This study aims to determine differences in the gallbladder contractility index using ultrasound in patients with and without liver cirrhosis. This study was an observational study of comparative analytic with cross-sectional design with sampling conducted by consecutive admissions sampling at Dr. Hasan Sadikin General Hospital Bandung from December 2017 to February 2018. Statistical analysis than performed by using an independent t test to find out the difference of gallbladder contractility index in patients with and without liver cirrhosis. A total of 22 subjects, 12 men, 10 women, with the youngest 37 years old and the oldest 70 years old. The result of the study was obtained mean fasting gallbladder volume (35.56±22.16 mL) and postprandial (21.25±16.08 mL) in patients with liver cirrhosis higher than without liver cirrhosis with mean fasting gallbladder volume (16.50±4.14 mL) and postprandial (5.44±2.10 mL). The average gallbladder contractility index on patients with liver cirrhosis (41.64±24.52%) smaller than without liver cirrhosis (66.73±9.19%). The result of the statistical test showed that there was a significant difference in the gallbladder contractility index on patients with liver cirrhosis than without liver cirrhosis (p=0.007, p≤0.05). In conclusion, there was a significant difference in the gallbladder contractility index that measured by using ultrasound between the patients with and without liver cirrhosis. PERBEDAAN INDEKS KONTRAKTILITAS KANDUNG EMPEDU MENGGUNAKAN ULTRASONOGRAFI PADA PENDERITA SIROSIS HATI DAN TANPA SIROSIS HATISirosis hati menyebabkan gangguan indeks kontraktilitas kandung empedu yang mengakibatkan stasis cairan empedu dan memudahkan kejadian batu empedu yang akan memperberat gejala klinis pasien. Indeks kontraktilitas kandung empedu merupakan indikator motilitas kandung empedu yang diukur menggunakan ultrasonografi (USG) sebagai modalitas pilihan radiologi. Penelitian ini bertujuan mengetahui perbedaan indeks kontraktilitas kandung empedu menggunakan ultrasonografi pada pasien sirosis hati dan tanpa sirosis. Penelitian ini menggunakan studi observasional analitik komparatif dengan rancangan cross-sectional dan pengambilan sampel dilakukan secara consecutive admissions sampling di RSUP Dr. Hasan Sadikin Bandung dari bulan Desember 2017 hingga Februari 2018. Uji statistik menggunakan independent t test. Subjek penelitian berjumlah 22, laki-laki 12 dan perempuan 10, serta usia termuda 37 tahun dan tertua 70 tahun. Hasil penelitian didapatkan volume rerata kandung empedu puasa (35,56±22,16 mL) dan pascaprandial (21,25±16,08 mL) pada pasien sirosis hati lebih besar daripada tanpa sirosis hati dengan volume rerata kandung empedu puasa (16,50±4,14 mL) dan pascaprandial (5,44±2,10 mL). Indeks kontraktilitas rerata kandung empedu penderita sirosis hati (41,64±24,52%) lebih rendah dibanding dengan tanpa sirosis hati (66,73±9,19%). Hasil uji statistik menunjukkan terdapat perbedaan bermakna antara indeks kontraktilitas kandung empedu penderita sirosis hati dan tanpa sirosis hati (p=0,007; p≤0,05). Simpulan, terdapat perbedaan bermakna antara indeks kontraktilitas kandung empedu menggunakan USG pada penderita sirosis hati dan tanpa sirosis hati.