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PENGARUH PEMBERIAN JINTAN HITAM (N.SATIVA) TERHADAP KADAR LDL PADA PASIEN DIABETES MELLITUS TIPE 2 DI RUMAH SAKIT UMUM DAERAH DELI SERDANG NUZUL MUHAMMAD NASUTION; FANI ADE IRMA
JURNAL ILMIAH SIMANTEK Vol 4 No 4 (2020): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

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Type 2 Diabetes Mellitus (Type 2 DM) used to be called non- insulin-dependent or adult-onset diabetes caused by noteffective insulin using for the body. In many researches it is found that the amount of incident average of type 2 DMincreases rapidly in the world. Indonesia is one of the country with the most accusative in seven grade of world table. Thedevelompment of this is done on and on by many researches. One of them is the research of black cumin (N.Sativa). It isused to know the influences of cholesterol of DM accusative. The purpose of the study was to determine the effect of givingBlack Cumin (N.sativa) to LDL levels in Type 2 Diabetes Mellitus patients at Deli Serdang General Hospital. This type ofresearch is experimental using pretest post test control group design. Subjects in this study were DM type 2 patients in theDeli Serdang General Hospital with a total of 18 subjects divided into 2 groups namely 9 control group subjects and 9standard group subjects. This research technique uses purposive sampling and data analysis using Paired t-test. Retrievingdata through laboratory results. The average LDL level in the pre-test control group was 109.89 and the average post-testscore was 105.67. In the standard pre-test group the average LDL level was 111.0 and the average post-test score was91.5. There is a significant difference between LDL levels before and after administration of black cumin (N.sativa).
EFEK PEMBERIAN REBUSAN KULIT JENGKOL (ARCHIDENDRON PAUCIFLORUM) SEBAGAI ANTIDIABETIK TERHADAP KADAR MALONDIALDEHYDE (MDA) TIKUS PUTIH YANG DIINDUKSI STREPTOZOTOCIN RADEN FEBRIAN DWI CAHYO EDI PRABOWO; FANI ADE IRMA
JURNAL ILMIAH SIMANTEK Vol 4 No 4 (2020): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

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Diabetes mellitus is a metabolic disorder with many symptoms where an increase in oxidative stress plays an important rolein the pathogenesis of disease and can lead to the formation of reactive oxygen species (ROS) so as to increase freeradicals. lipids will eventually produce aldehydes, one of which is malondialdehyde (MDA) which is commonly used as abiological biomarker of lipid peroxidation and describes the degree of oxidative stress. This study aimed to determine theeffect of giving jengkol cooking water on malondialdehyde (MDA) levels in blood plasma of streptozotocin-induced malewistar rats (Rattus novergicus L.) white rats. True experimental posttest only control group design. Significant results ofplasma malondialdehyde (MDA) levels between the control and treatment groups were p> 0.05. The administration ofjengkol decoction with 80% concentration at a dose of 40 mg / KgBB / rat / day for 14 days affected the decrease in plasmaMDA previously streptozotocin induced.
PENGARUH SENAM DIABETES TERHADAP INDEKS MASSA TUBUH DAN TEKANAN DARAH PADA PENDERITA DIABETES MELLITUS TIPE 2 DI KLINIK TIARA MEDISTRA DESA BANDAR SETIA ZAKIYAH DARAJAT; FANI ADE IRMA
JURNAL ILMIAH SIMANTEK Vol 4 No 4 (2020): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

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Diabetes is a multifactorial disease thats every year is an increase in new diabetics, diabetes disrupts the metabolism ofendocrine system and can affect all organs of the body, especially the cardiovascular system. Exercise has an important rolein patients controling blood pressure and weight. Low impact aerobics are sport recomendations for diabetic patients toincrease insulin sensitivity. To determine the effect of diabetes exercise on the patient's body weight which is affect the bodymass index and blood pressure of type 2 diabetes mellitus patients at Tiara medistra clinic-Bandar Setia. This is aquantitative research using Quasi experiments with one group pre and post test. This result of this study used the Shapiro-Wilk normality test. The value of the results of this analysis is 0.013 (p <0.05) in systolic blood pressure, 0.002 (p <0.05) indiastolic blood pressure, and 0.012 (p <0.05) in body mass index. From the results of this study it was concluded thatdiabetes exercise for 30 minutes affected blood pressure and body mass index.
PENGARUH PEMBERIAN MADU TERHADAP KADAR ALBUMIN PLASMA TIKUS PUTIH (Rattus norvegicus L.) JANTAN GALUR WISTAR YANG DI INDUKSI TUAK MUHAMMAD EGGA ACHYAR RAHMAN; ROBITAH ASFUR; FANI ADE IRMA; EMNI PURWONINGSIH
JURNAL ILMIAH KOHESI Vol 3 No 3 (2019): JURNAL ILMIAH KOHESI
Publisher : LP2MTBM MAKARIOZ

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Abstract

Tuak is the result of fermentation of leads taken from aren (Arenga pinnata) containing 88% water, 11.8% carbohydrate, 0.23% protein, 0.02% fat, 0.03% minerals and 5% alcohol. Alcohol metabolism in liver cells leads to an increase in free radicals resulting in oxidative stress that damages tissues in the liver. Objective: This study aims to determine the effect of giving honey on white rats (Rattus norvegicus L.) male wistar-induced strain of tuak. Method: True experiment design "prettest-posttest with control group design". Results: Significant results of plasma albumin levels between control and treatment groups were p> 0.05. Conclusion: Provision of honey 1.35 mL /rat/ day for 15 days had an effect on the increase of plasma albumin level which previously decrease due tuak 2.5 mL /rat/ day for 15 days.
PENGARUH PEMBERIAN EKSTRAK BIJI PEPAYA (CARICA PAPAYA LINN) TERHADAP KADAR HDL PADA TIKUS PUTIH JANTAN GALUR WISTAR (RATTUS NORVEGICUS) YANG DIINDUKSI DIET TINGGI LEMAK SUKMA DWI KARTIKA; ILHAM HARIAJI; FANI ADE IRMA; YENITA .
JURNAL ILMIAH KOHESI Vol 5 No 3 (2021): JURNAL ILMIAH KOHESI
Publisher : LP2MTBM MAKARIOZ

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Cardiovascular disease is the leading cause of death globally, totaling 17.7 million in 2015, representing 31% of all globaldeaths. The death rate of cardiovascular disease that increases every year is Coronary Heart Disease. Modern diets thatcontain lots of cholesterol, accompanied by high food intensity, obesity such as low activity make blood cholesterol levelsdifficult to control so that it can cause dyslipdemia. Experimental Research With Pretest-Posttest Method with control groupdesign. This study used male Wistar rats (Rattus novergicus) induced by a high-fat diet. Where divided into 4 groups, dividedinto negative control, negative control, first treatment (400mg / tail) and second treatment (800mg/tail ). Takes before andafter a diet and a high-fat diet are taken. In this study, the results obtained with the t-test p <0.05, which means that there is arelationship between the provision of papaya seed extract and an increase in HDL levels. In the research results where thedose of 400mg/tail can increase HDL cholesterol levels in the blood. There was a significant relationship between papayaseed extract and the increase in HDL levels in male Wistar rats.
HUBUNGAN GAMBARAN HASIL PEMERIKSAAN FOTO THORAX DENGAN KEPOSITIVAN HASIL PEMERIKSAAN SPUTUM PADA PENDERITA TB PARU DI RSUD PEMERINTAH KABUPATEN ACEH TIMUR PERIODE JANUARI 2018 - AGUSTUS 2019 KHEMAL MUBARAQ; FANI ADE IRMA
JURNAL ILMIAH KOHESI Vol 5 No 3 (2021): JURNAL ILMIAH KOHESI
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Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium Tuberculosis, which can attack variousorgans, especially the lungs. The source of transmission is TB patients, especially patients who contain TB germs in theirsputum. When coughing or sneezing, the patient spreads germs into the air in the form of sputum sputtering (droplet nuclei).Infection will occur if someone breathes in air that contains infectious sputum splashes. One cough can produce about 3000sputum sputum which contains as many as 0- 3500 Mycobacterium Tuberculosis. Meanwhile, if you sneeze can issue asmany as 4500 - 1,000,000 Mycobacterium Tuberculosis. The purpose of this research is to find out the relationship betweenthe description of the results of the thorax photo examination with the results of sputum examination in patients withpulmonary TB in RSUD Sultan Abdul Aziz Syah Peureulak. This type of research is analytic with cross sectional studydesign. The number of samples in this study were 37 respondents obtained using total sampling. The results of this studyindicate there is a relationship between the results of the examination of the chest radiograph with the results of sputumexamination in patients with pulmonary TB (Pvalue = 0,000). Suggestions to all parties, both the RSUD Sultan Abdul AzizSyah Peureulak, the Local Health Service, and the community to work together in deciding the transmission of pulmonaryTB.
HUBUNGAN RIWAYAT KONTAK ANTAR PASANGAN TERHADAP PENULARAN TB PARU KASUS BARU BERDASARKAN HASIL PEMERIKSAAN BTA DI PUSKESMAS PEUREULAK KAB. ACEH TIMUR BUDI SUBHANA MAULANA IBRAHIM TAMBUNAN; FANI ADE IRMA; SRI REZEKI ARBANINGSIH; RIZKA ARIANI
JURNAL ILMIAH KOHESI Vol 5 No 3 (2021): JURNAL ILMIAH KOHESI
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The design of this study was cross sectional using the Chi Square test. The number of samples used was 44 respondentswho were positive for pulmonary tuberculosis with BTA +1, +2 and +3 and the results of BTA from the pairs of respondents.The results of the data analysis indicated that there was a relationship between the contact history between husband andwife and the transmission of new cases of pulmonary TB based on the results of the BTA examination at the PeureulakHealth Center, East Aceh Regency. The results of statistical tests using Chi Square showed a value (P = 0.001). Meanwhile,based on the BTA of respondents, it was found that there was no relationship between sex and age on the BTA of therespondents with P-values of 0.986 and 0.250 respectively. Then based on the AFB couples also obtained the results thatthere was no relationship between sex and age on the AFB couples with each P-value of 0.068 and 0.394. Based on theresults of the description above, it can be concluded that there is a relationship between the history of contact betweenhusband and wife partners to the transmission of new cases of pulmonary TB based on the results of the BTA examination atthe Peureulak Health Center, East Aceh Regency.
Profil Kuman Pada Penderita Omsk Dengan Kultur Swab Di Rs Haji Medan Sofi Tamara Lubis; Siti Masliana Siregar; Fani Ade Irma; Annisa Annisa
ANATOMICA MEDICAL JOURNAL | AMJ Vol 3, No 1 (2020)
Publisher : Universitas Muhammadiyah Sumatera Utara

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Abstract

Introduction: Chronic suppurative otitis media (CSOM) is a chronic inflammation or infection of the middle ear which is indicated by a tympanic membrane perforation and otorrhea occurring over 2 months of repetitive or persistent settling. The aim of this study is to know the the most common bacteria occured in CSOM. Methods: This was a descriptive cross-sectional study. The subjects consisted of all CSOM patients in October 2017 to December 2017 period who met inclusion criterias Results: There was 27 patients included in this study which consisted of  21 (77.8%) men and 6 (22.2%) women. The age range of <10 years was 21 (77.8%) subjects. Staphylococcus aureus is the most common bacteria presented in CSOM which was 10 (37%) subjects. Proteus sp was the  most common bacteria presented in the age range of  <10 year.  Conclusion: bacterias identified in CSOM are Proteus sp., Staphylococcus aureus, Streptococcus, Pseudomonas auregenosa, and Aerobacter.Keywords: bacteria, CSOM, Sthaphylococcus
Pengaruh merokok terhadap hasil clotting time dan bleeding time pada populasi laki-laki Fakultas Kedokteran UMSU Dhio Emerko Ginting; Fani Ade Irma; Sri Rezeki Arbaningsih; Siti Hajar
Sriwijaya Journal of Medicine Vol. 2 No. 1 (2019): Vol 2, No 1, 2019
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v2i1.28

Abstract

WHO telah menetapkan Indonesia sebagai negara dengan jumlah perokok terbesar ketiga. Ada tiga zat kimia yang paling sangat berbahaya, yaitu tar, nikotin, karbon monoksida yang terkandung dalam rokok. Hasil penelitian di Inggris menunjukkan kepada kita bahwa kurang lebih 50% perokok yang merokok sejak remaja mengalami kematian akibatpenyakit yang berhubungan dengan kebiasaan merokok mereka. Penelitian ini bertujuan untuk mengetahui tentang pengaruh asap rokok dengan proses kaskade clotting time. Jenis penelitian ini adalah penelitian analitik dengan menggunakan desain cross-sectional. Penelitian ini menggunakan sampel populasi laki-laki di Fakultas Kedokteran di UMSU yang diwawancara untuk mengetahui bahwa mereka merokok atau tidak, setelah itu, sampel diperiksa clotting time dan bleeding time. Data yang terkumpul dianalisis dengan uji chi-square. Hasil penelitian menunjukkan p = 0,000 bahwa ada hubungan merokok dengan clotting time dan bleeding time pada perokok berat dan sedang. Pada perokok berat dan moderat terdapat hubungan bermakna antara penurunan bleeding time dan peningkatan clotting time dengan merokok. Tidak ada hubungan antara clotting time dan merokok pada perokok ringan.
KADAR SERUM BESI PADA ANAK YANG TERINFEKSI SOIL TRANSMITTED HELMINTS DI DESA KUTAMBALIN KECAMATAN NAMAN TERAN SUMATERA UTARA NUR FATIMAH; FANI ADE IRMA
JURNAL ILMIAH SIMANTEK Vol 6 No 4 (2022): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

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Worm disease is widespread, both in rural and urban areas. The infection rate is high, but the frequency of infection (number of worms in the stomach) is different. Indonesia ranks second in the Southeast Asian region for deworming treatment needs in children with a percentage of 15% after India is the first priority with a percentage of 61%. The negative impacts that can occur due to STH are declining health conditions, gastroenteritis, diarrhea, pneumonia, asthma, appendicitis, and malnutrition which can cause anemia, vitamin and iron deficiency, thereby inhibiting physical growth and development,Iron deficiency anemia can have an impact on physical growth, the development of brain intelligence, and increase the risk of decreased immunity which makes a person susceptible to infection. This study uses an observational research method with a cross sectional approach. The subjects in this study were the children of SD Negeri Kutambalin, Naman Teran sub-district, North Sumatra. With a sample of 16 children. Data analysis used fisher's exact test. From 16 samples, stool examination was performed using the diret slide method, it was found that 4 (25%) samples had STH infection and on blood examination 1 (6.25%) samples experienced a decrease in serum iron levels. Based on the results of this study, it was found that there was no decrease between serum iron levels in the blood and the incidence of STH infection