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UJI EFEKTIVITAS ANTIBIOTIK EKSTRAK DAUN CENGKEH (SYZYGIUM AROMATICUM) TERHADAP PERTUMBUHAN BAKTERI SALMONELLA TYPI SECARA IN VITRO Ristiansyah, Dilla Ulfa; Yenita, Yenita; Melviana, Melviana; Annisa, Annisa
JURNAL IBNU SINA BIOMEDIKA Vol 2, No 1 (2018)
Publisher : UNIVERSITAS MUHAMMADIYAH SUMATERA UTARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (531.486 KB) | DOI: 10.30596/isb.v2i1.1901

Abstract

Typhoid fever is an enteric bacterial infection caused by Salmonella enterica serovar Typhi or Paratyphi. Salmonella typhi is a Gram negative rod which has no spores and moves with flagel peritric. Salmonella is facultative intracellular and facultative anaerobes. Clove leaves (Syzygium aromaticum) have antibiotic effects on bacteria and known can inhibit Salmonella typhi bacteria. Methodology: This study used an experimental method. The technique used in measuring antibiotic activity is the method of disk diffusion. Result: The concentration of 10%, 15%, 20% and 25% clove leaf extracts resulted in average of 11.89 mm, 11.40 mm, 16.76 mm, and 16.90 mm respectively. while the clear zone diameter of chloramphenicol is 20.74 mm.Conclusion: Clove leaf extract at 25% concentration has high clear zone in treatment group. Keywords: Salmonella typhi, Clove Leaf extractKeywords : Salmonella typhi, Cengke leaf’s extract    
PENGEMBANGAN METODE BELAJAR DAN MELATIH SKILL MAHASISWA FAKULTAS KEDOKTERAN UNIVERSITAS MUHAMMADIYAH DI KLINIK AISYIYAH DI KOTA MEDAN Asfur, Robitah; Yenita, Yenita; Nurfadly, Nurfadly
JURNAL PRODIKMAS Hasil Pengabdian Kepada Masyarakat Vol 4, No 1 (2019)
Publisher : Universitas Muhammadiyah Sumatera Utara

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Abstract

Pengembangan setiap Fakultas Kedokteran memang merupakan target pasar dalam persaingan untuk merekrut minat setiap calon mahasiswa, mengingat Muhammadiyah besar dalam amal usahanya baik di bidang pendidikan dan bidang kesehatan, Fakultas Kedokteran Universitas Muhammadiyah Sumatera utara memiliki keunggulan besar karena amal usaha dibidang kesehatan berupa rumah sakit muhammadiyah dan klinik aisyiyah di seluruh daerah dan cabang. Tujuan program kegiatan Ipteks bagi Inovasi Kreativitas Kampus Fakultas Kedokteran Universitas Muhammadiyah Sumatera Utara adalah Inovasi metode belajar dan melatih skill mahasiswa sebelum menuju praktek di rumah sakit (Koas). Beberapa program yang akan dikembangkan adalah melatih kemampuan belajar mahasiswa, mengasah skill seperti partus normal, immunisasi, edukasi dan mempelajari program BPJS. Program lain yang diberikan oleh klinik Aisyiyah adalah memberi penyuluhan kesehatan di pengajian ? pengajian ibu ? ibu Aisyiyah, edukasi sekolah untuk mengaktifkan UKS yang ada di sekolah dan belajar Home visite yang diberikan klinik Aisyiyah kepada warga yang tidak dapat datang berobat langsung ke klinik Aisyiyah sehingga mahasiswa mulai terbiasa dengan kegiatan sebagai dokter yang bekerja di faske pertama. Rencana ke depan yang ingin dicapai FK UMSU adalah menjadikan FK UMSU lebih besar lagi, dan menjadi pusat unggulan dan terpercaya dalam dunia pendidikan dan dunia kesehatan yang memiliki nilai Muhammadiyah dan Aisyiyah setiap lulusan FK.UMSU.
UJI EFEKTIVITAS ANTIBAKTERI EKSTRAK DAUN BELIMBING WULUH (AVERRHOA BILIMBI L) TERHADAP PERTUMBUHAN BAKTERI KLEBSIELLA PNEUMONIAE SECARA IN VITRO FIRSTY DWI HIDAYATI SIRAIT; YENITA .; ANCE ROSLINA; ILHAM HARIAJI
JURNAL ILMIAH MAKSITEK Vol 5 No 4 (2020): JURNAL ILMIAH MAKSITEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Infection is the most common disease in Indonesia. Infection disesase are caused by microorganisms such as the Klebsiellapneumoniae. While in fact, many plants can be used as traditional medicine, one of those is the leaves of Cucumber tree(Averrhoa bilimbi L). This study aims to determine the inhibitory power of leaves of Cucumber tree (Averrhoa bilimbi L) ongrowth of Klebsiella pneumoniae in vitro. This study used an experimental method. The technique used to measureantibiotic activity is the method of disk diffusion and continued by Kruskal-Wallis test and Mann-Whitney test Leaves ofCucumber tree (Averrhoa bilimbi L) at concentrations of 40%, 60%, 80%, 100%, cefotaxime, and aquabidest shows no clearzone. Leaves of Cucumber tree (Averrhoa bilimbi L) does not have an inhibitory power against Klebsiella pneumoniae.
GAMBARAN KEJADIAN VITILIGO DI RSUD DR. RM DJOELHAM KOTA BINJAI PERIODE 1 JANUARI 2015 - 1 SEPTEMBER 2019 HERVINA .; YENITA .
JURNAL ILMIAH MAKSITEK Vol 6 No 2 (2021): JURNAL ILMIAH MAKSITEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Vitiligo is a pigmentation disorder, characterized by hypopigmented macules caused by chronic and progressive loss ofepidermal melanocyte function. The cause of vitiligo is not yet known with certainty the cause. According to some studies theincidence of vitiligo is more frequent in women, aged 20-40 years and in students. This study uses a descriptive method witha retrospective approach. Data were obtained from the medical records of vitiligo patients in the period January 1 2015 -September 1 2019. In January 2015 - September 2019 in Dr. RM Djoelham Binjai City found the highest incidence of vitiligooccurred in women as many as 35 people (63.6%), the incidence of age was more prevalent at the age of 11-20 years asmany as 17 people (30.9%), the incidence based on more work many occur in students as many as 20 people (36.4%).Based on the results of a study describing the incidence of vitiligo in the Skin and Sex Health clinic Dr. RM Djoelham KotaBinjai mostly occurs in women, the incidence of age mostly occurs at the age of 11-20 years and the incidence of work ismore common in students.
PROFIL PASIEN DEMAM TIFOID DAN PENGOBATAN DI BAGIAN PENYAKIT DALAM RUMAH SAKIT PIRNGADI MEDAN TAHUN 2016 MUHAMMAD FADHIL; NELLI MURLINA; YENITA .; SHAHRUL RAHMAN
JURNAL ILMIAH SIMANTEK Vol 5 No 1 (2021): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

The type of research used in this study is a descriptive study with a cross sectional design to determine the profile andtreatment of typhoid fever patients in the internal medicine department of Pirngadi hospital Medan in 2016 through medicalrecord data. Based on the genitalia, male as many as 33 samples and females as many as 49 samples. Based on the age,teenager as many as 6 samples, young adults as many as 47 samples, adults as many as 27 samples, elderly as many as 2samples. Based on the work, students as many as 6 samples, college student as many as 21 samples, goverment employeeas many as 7 samples, entrepeneur as many as 15 samples, private employees as many as 10 samples, retirees as manyas 4 samples, farmers as much as 2 samples, housewife as many as 14 samples, unemploymeent 3 people. Based on thetreatment of antibiotics, cifrofloxacin as many as 25 samples, levofloxacin as many as 9 samples, ceftriaxone as many as 37samples, cefixime as many as 7 samples, cefadroxyl as many as 1 sample, cefotaxime 1 sample, cotrimoxazole 1 sample.Based on antipyretic treatment, as many as 82 samples of paracetamol.
UJI EFEKTIVITAS ANTIBIOTIK EKSTRAK DAUN BELIMBING WULUH (AVERRHOA BILIMBI L.) DAN EKSTRAK HABATUSSAUDA (NIGELLA SATIVA L.) TERHADAP PENYEMBUHAN LUKA SAYAT MENCIT JANTAN (MUS MUSCULUS L.) YANG TERINFEKSI STAPHYLOCOCCUS AUREUS SECARA IN VIVO SARAH RAISAH ZEIN HARAHAP; YENITA .
JURNAL ILMIAH KOHESI Vol 5 No 2 (2021): JURNAL ILMIAH KOHESI
Publisher : LP2MTBM MAKARIOZ

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Abstract

Each person will experience several types of infections, one of which is a skin infection caused by the bacteriumStaphylococcus aureus, because this bacterium is the main pathogen for humans. Excessive use of antibiotics in thetreatment of infections can cause bacterial resistance because the uncontrolled us of antibiotics will increase resistance tobacteria that were previously sensitive.Starfruit leaves (Averrhoa bilimbi L.) contain flavonoid and triterpenoid compositionsthat can cure the special bacterial disease Staphylococcus aureus available on skin. Besides starfruit (Averrhoa bilimbi L.)can also use habatussdauda (Nigella sativa L.) which contains bioactive thymoquinone, oleic acid, linoleic acid and saponinsto enhance the body immune system and anti-inflammator. To determine the effectiveness of antibiotic extract of starfruit leafextract (Averrhoa bilimbi L.) with habatussauda extract (Nigella sativa L.) on wound healing in male mice (Mus musculus L.)infected with Staphylococcus aureus. Experimental research with Pre-test and Post test design with Control Group Designmethod. Starfruit leaf extract (Averrhoa bilimbi L.) with the lowest dose can reduce the length of the wound significantlycompared to habatussauda (Nigella sativa L.) extract. Starfruit leaf extract (Averrhoa bilimbi L.) with a dose of 200mg/kgBB/day more effectively can heal the length of the cut.
UJI EFEKTIVITAS ANTIBIOTIK EKSTRAK DAUN BELIMBIMG WULUH (AVERRHOA BILIMBI L) DAN EKSTRAK HABATUSSAUDA (NIGELLA SATIVA L) TERHADAP JUMLAH LEUKOSIT MENCIT JANTAN (MUS MUSCULUS L) YANG TERINFEKSI STAPHYLOCOCCUS AUREUS SIGIT KURNIAWAN; YENITA .
JURNAL ILMIAH KOHESI Vol 5 No 2 (2021): JURNAL ILMIAH KOHESI
Publisher : LP2MTBM MAKARIOZ

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Abstract

Infectious disease is a disease caused by microorganisms that attack host, one of which is skin infection by Staphylococcusaureus. Some types of diseases that can be caused by Staphylococcus aureus infections are pyoderma, nosocomialinfections, infections of wounds, food poisoning, and toxic shock syndrome. Indonesian people have long been applyingtraditional medicine, using plants that are believed to be efficacious to treat diseases. Plants that can be used as traditionalmedicine are leaves of starfruit and habatussauda starfruit. Based on previous research, this plant contains compounds thatare as antibacterial. To determine the effectiveness of antibiotic extract of starfruit leaf extract (Averrhoa bilimbi L) withhabatussauda extract (Nigella sativa L) on the number of leukocytes in male mice (Mus musculus L) infected withStaphylococcus aureus. This study is an experimental study with a Post test with Control Group Design method. Mice weredivided into 6 groups namely K (-), K (+), P1, P2, P3 and P4 with a total sample of 6 groups. All mice were cut on the backand infected with Staphylococcus aureus. Administered orally by force-feeding. Based on the results of hypothesis testingwith the Kruskal Walis test p value = 0.007 (p <0.05), there were significant differences in the number of leukocytes in the 6study groups. There was a difference in effectiveness in reducing the number of leukocytes in male mice infected withStaphylococcus aureus in the treatment group. Group K (+) is the most effective group to reduce the number of leukocytes.Then followed by groups P4, P3, P2 and P1.
PENGARUH PEMBERIAN EKSTRAK BIJI PEPAYA (CARICA PAPAYA LINN) TERHADAP KADAR HDL PADA TIKUS PUTIH JANTAN GALUR WISTAR (RATTUS NORVEGICUS) YANG DIINDUKSI DIET TINGGI LEMAK SUKMA DWI KARTIKA; ILHAM HARIAJI; FANI ADE IRMA; YENITA .
JURNAL ILMIAH KOHESI Vol 5 No 3 (2021): JURNAL ILMIAH KOHESI
Publisher : LP2MTBM MAKARIOZ

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Abstract

Cardiovascular disease is the leading cause of death globally, totaling 17.7 million in 2015, representing 31% of all globaldeaths. The death rate of cardiovascular disease that increases every year is Coronary Heart Disease. Modern diets thatcontain lots of cholesterol, accompanied by high food intensity, obesity such as low activity make blood cholesterol levelsdifficult to control so that it can cause dyslipdemia. Experimental Research With Pretest-Posttest Method with control groupdesign. This study used male Wistar rats (Rattus novergicus) induced by a high-fat diet. Where divided into 4 groups, dividedinto negative control, negative control, first treatment (400mg / tail) and second treatment (800mg/tail ). Takes before andafter a diet and a high-fat diet are taken. In this study, the results obtained with the t-test p <0.05, which means that there is arelationship between the provision of papaya seed extract and an increase in HDL levels. In the research results where thedose of 400mg/tail can increase HDL cholesterol levels in the blood. There was a significant relationship between papayaseed extract and the increase in HDL levels in male Wistar rats.
Uji Efektivitas Antibiotik Ekstrak Daun Kayu Manis (Cinnamomum Burmannii) Terhadap Pertumbuhan Bakteri Salmonella Typhi Secara In Vitro Lestari Safitri; Yenita Yenita
ANATOMICA MEDICAL JOURNAL | AMJ Vol 3, No 1 (2020)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (603.468 KB) | DOI: 10.30596/anatomica

Abstract

IIntroduction: Salmonella typhi is a rod-shaped or bacillus, gram negative, facultative anaerobic, moves with peritric flagella, and it doesn’t produce spores. Salmonella is pathogenic for humans or animals if obtained from the oral route. Cinnamon leaf (Cinnamomum burmannii) has antibiotic effect on bacteria. Flavonnoid, saponin, alkaloid, and tannin on cinnamon leaves is known to inhibit Salmonella typhi bacteria. Methodology: This study used an experimental method. The technique used in measuring antibiotic activity is the method of disk diffusion. Result: The result of the research showed that cinnamon leaf extract (Cinnamomum burmannii) with concentration of 80%, 40%, 20%, and 10% yielded average of clear zone diameter 17,863 mm, 13,692 mm, 10,352 mm, and 9.79 mm. While the diameter of the clear zone of chloramphenicol is 19.72 mm and the aquadest is not obtained clear zone. Conclusion: Cinnamon leaf extract with 80% concentration has the highest clear zone in the treatment groupKeywords: Salmonella typhi, cinnamon leaf extract
Tinjauan Efektifitas Minyak Perawan Buah Kelapa Terhadap Penurunan Kadar Gula Darah Yenita FK UMS
Buletin Farmatera Vol 1, No 2 (2016)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (173.16 KB) | DOI: 10.30596/bf.v1i2.840

Abstract

Kesehatan  adalah  harta   manusia   yang  paling  berharga.  Manusia   tidak jarang  harus  mengeluarkan  biaya   sedikit untuk memulihkan kesehatan yang terganggu. Diabetes melitus merupakan penyakit kronis metabolik yang memerlukan pengelolaan seumur hidup baik pengobatan farmakologis maupun non farmakologis. Salah satu masalah besarnya biaya pengobatan jangka panjang, sehingga perlu mencari obat antidiabetes yang relatif murah dan terjangkau masyarakat. Sebagai salah satu alternatif adalah dengan menggali khasanah budaya bangsa melalui penelitian tentang obat tradisional yang sudah lama digunakan masyarakat Indonesia.Pohon kelapa telah mendampingi kehidupan bangsa Indonesia sejak jaman nenek moyang ribuan tahun yang silam. Nenek moyang kita juga telah memahami pohon kelapa memiliki daya guna yang cukup tinggi, semua bagian pohon kelapa memberi manfaat bagi kehidupan sehari-hari bangsa Indonesia.1 Minyak kelapa sejak dulu digunakan di dapur oleh emak-emak dan sang nenek menyemir rambutnya dengan menggunakan minyak kelapa . Mengonsumsi minyak kelapa sebagai obat, juga sudah dikenal oleh masyarakat Indonesia misalnya, ibu yang akan melahirkan selalu dianjurkan untuk mengonsumsi minyak kelapa setengah gelas menjelang melahirkan. Khasiatnya agar proses persalinan menjadi lebih mudah dan lancar. Tidak hanya itu, ASI pun menjadi lebih lancar.2Minyak kelapa murni/VCO  merupakan salah satu hasil olahan dari buah kelapa (Coconos nicifera). Tanaman kelapa banyak tumbuh di daerah tropis  sehingga minyaknya disebut juga minyak tropis (tropical oil). Pada tahun 1950-an para peneliti Amerika menganggap minyak kelapa adalah penyebab penyakit jantung dan pembuluh darah. Namun pada tahun 1954 peneneliti muda bernama, David Kritchevsky membantahnya dengan mempublikasikan dari hasil penelitiannya.3Saat ini boleh dikatakan VCO adalah karunia Allah SWT kepada umat manusia, terutama untuk kesehatan.2             VCO dapat digunakan dalam pencegahan maupun pengobatan  berbagai penyakit (panacea), diantaranya penyakit diabetes melitus . Diabetes melitus adalah suatu kondisi dimana konsentrasi glukosa dalam darah tinggi  (hiperglikemia) akibat dari kekurangan insulin atau fungsi insulin tidak efektif. Penyakit ini telah dikenal ribuan tahun yang lalu dan kini dikenal sebagai penyakit akibat dari pola hidup modern.